Second-line docetaxel and gemcitabine combination chemotherapy in patients with non-small-cell lung cancer previously treated with platinum-based chemotherapy: A phase II trial

Medical Oncology

Volumn 21, Issue 3, 2004, Pages 233-240

  Tas, Faruk ^a   Demir, Cumhur ^a   Camlica, Hakan ^a   Ustuner, Zeki ^a   Topuz, Erkan ^a  

^a ISTANBUL UNIVERSITY   (Turkey)

Author keywords

Chemotherapy; Docetaxel; Gemcitabine; Non small cell lung cancer; Second line

Indexed keywords

ANTIFUNGAL AGENT; BENZYDAMINE; CISPLATIN; DEXAMETHASONE; DOCETAXEL; ETOPOSIDE; GEMCITABINE; GRANULOCYTE COLONY STIMULATING FACTOR RECEPTOR; LOPERAMIDE; NAVELBINE;

ADULT; AGED; ANEMIA; ARTICLE; ASTHENIA; BLOOD TOXICITY; CANCER COMBINATION CHEMOTHERAPY; CANCER SURVIVAL; CHEMOTHERAPY INDUCED EMESIS; CLINICAL ARTICLE; CLINICAL TRIAL; CONSTIPATION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIARRHEA; DOSE RESPONSE; DRUG DOSE REDUCTION; DRUG EFFICACY; DRUG FEVER; DRUG INFUSION; DRUG RESISTANCE; DRUG RESPONSE; DRUG SAFETY; DRUG SENSITIVITY; EDEMA; FEBRILE NEUTROPENIA; FEMALE; FLU LIKE SYNDROME; FOLLOW UP; HAIR DISEASE; HUMAN; INFECTION; LEUKOPENIA; LUNG DISEASE; LUNG NON SMALL CELL CANCER; MALE; MOUTH DISEASE; NAUSEA; NEUTROPENIA; PERIPHERAL NEUROPATHY; PHASE 2 CLINICAL TRIAL; PRIORITY JOURNAL; SKIN MANIFESTATION; STOMATITIS; THROMBOCYTOPENIA; VEIN DISEASE;

ADULT; AGED; ANTIMETABOLITES, ANTINEOPLASTIC; ANTINEOPLASTIC AGENTS, PHYTOGENIC; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CARCINOMA, NON-SMALL-CELL LUNG; CHI-SQUARE DISTRIBUTION; CISPLATIN; DEOXYCYTIDINE; DISEASE-FREE SURVIVAL; ETOPOSIDE; FEMALE; FOLLOW-UP STUDIES; HUMANS; LUNG NEOPLASMS; MALE; MIDDLE AGED; TAXOIDS; TIME FACTORS; VINBLASTINE;

EID: 7944221150     PISSN: 13570560     EISSN: None     Source Type: Journal    
DOI: 10.1385/MO:21:3:233     Document Type: Article

References (17)

1. Fossella FV. Docetaxel in the treatment of non-small-lung cancer: review of single-agent trials. Semin Oncol 1999; 26(Supp 16): 17-23.
2. Burris HA, Eckhardt J, Fields S. Phase II trials of Taxotere in patients with non-small-cell lung cancer. Proc ASCO 1993; 12:35A.
3. Fossella FV, et al. Phase II study of docetaxel for advanced or metastatic platinum-refractory non-small-cell lung cancer. J Clin Oncol 1995; 13:645-651.
4. Robinet G, Kleisbauer JP, Thomas P. Phase II study of docetaxel (Taxotere) in first- and second line NSCLC. Proc ASCO 1997; 16:480A.
5. Gandara D, et al. Activity of docetaxel in platinum-treated non-small-cell lung cancer: results of a phase II multicenter trial. J Clin Oncol 2000; 18:131-135.
6. Shepherd F, et al. Prospective randomized trial of docetaxel versus best supportive care in patients with non-small-cell lung cancer previously treated with platinum-based chemotherapy. J Clin Oncol 2000; 18:2095-2103.
7. Fossella FV, et al. Randomized phase III trial of docetaxel versus vinorelbine or ifosfamide in patients with advanced non-small-cell lung cancer previously treated with platinum-containing chemotherapy regimens. J Clin Oncol 2000; 18:2354-2362.
8. Rosvold E, Langer CJ, Schilder R, Millenson M, Riemet E, Kreamer K. Salvage therapy with gemcitabine in advanced non-small-cell lung cancer progressing after prior carboplatin-paclitaxel. Proc ASCO 1998; 17:467A.
9. Crino L, et al. Gemcitabine as second-line treatment for advanced non-small-cell lung cancer: a phase II study. J Clin Oncol 1999; 17:2081-2085.
10. Baas P, Codrington H, Muller M, Dalesio O, Kwa HB, Zandwijk N. Second-line gemcitabine therapy in non-small-cell lung cancer stage IIIB and IV. Proc ASCO 2000; 18:495A.
11. Spiridonidis CH, et al. Second-line chemotherapy for non-small-cell lung cancer with monthly docetaxel and weekly gemcitabine: a phase II trial. Ann Oncol 2001; 12:89-94.
12. Kosmas C, et al. Gemcitabine and docetaxel as second-line chemotherapy for patients with nonsmall cell lung carcinoma who fail prior paclitaxel plus platinum-based regimens. Cancer 2001; 92:2902-2910.
13. Kakolyris S, et al. Docetaxel in combination with gemcitabine plus rhG-CSF support as second-line treatment in non-small cell lung cancer. A multicenter phase II study. Lung Cancer 2001; 32:179-187.
14. Hainsworth JD, Burris III HA, Billings III FT, Bradof JE, Baker M, Greco FA. Weekly docetaxel with either gemcitabine or vinorelbineas second-line treatment in patients with advanced nonsmall cell lung carcinoma. Cancer 2001; 92:2391-2398.
15. Chen YM, Perng RP, Lin WC, Wu HW, Tsai CM, Whang-Peng J. Phase II study of docetaxel and gemcitabine combination chemotherapy in non-small-cell lung cancer patients failing previous chemotherapy. Am J Clin Oncol 2002; 25:509-512.
16. Rischin D, et al. A phase trial of docetaxel and gemcitabine in patients with advanced cancer. Ann Oncol 2000; 11:421-426.
17. Kosmas C, Tsavaris N, Kalofonos HP. Salvage chemotherapy with the gemcitabine/docetaxel combination in nonsmall cell lung cancer: an overview of recent phase II studies. Med Sci Monit 2002; 8:58-63.