-
1
-
-
23644446866
-
Akt1/protein kinase Balpha is critical for ischemic and VEGFmediated angiogenesis
-
Ackah E, Yu J, Zoellner S, Iwakiri Y, Skurk C, Shibata R et al. (2005). Akt1/protein kinase Balpha is critical for ischemic and VEGFmediated angiogenesis. J Clin Invest 115: 2119-2127.
-
(2005)
J Clin Invest
, vol.115
, pp. 2119-2127
-
-
Ackah, E.1
Yu, J.2
Zoellner, S.3
Iwakiri, Y.4
Skurk, C.5
Shibata, R.6
-
2
-
-
0037229714
-
Overexpression of AKT2/protein kinase Bbeta leads to up-regulation of beta1 integrins, increased invasion, and metastasis of human breast and ovarian cancer cells
-
Arboleda MJ, Lyons JF, Kabbinavar FF, Bray MR, Snow BE, Ayala R et al. (2003). Overexpression of AKT2/protein kinase Bbeta leads to up-regulation of beta1 integrins, increased invasion, and metastasis of human breast and ovarian cancer cells. Cancer Res 63: 196-206.
-
(2003)
Cancer Res
, vol.63
, pp. 196-206
-
-
Arboleda, M.J.1
Lyons, J.F.2
Kabbinavar, F.F.3
Bray, M.R.4
Snow, B.E.5
Ayala, R.6
-
3
-
-
67650558915
-
Recruitment of vimentin to the cell surface by beta3 integrin and plectin mediates adhesion strength
-
Bhattacharya R, Gonzalez AM, Debiase PJ, Trejo HE, Goldman RD, Flitney FW et al. (2009). Recruitment of vimentin to the cell surface by beta3 integrin and plectin mediates adhesion strength. J Cell Sci 122: 1390-1400.
-
(2009)
J Cell Sci
, vol.122
, pp. 1390-1400
-
-
Bhattacharya, R.1
Gonzalez, A.M.2
Debiase, P.J.3
Trejo, H.E.4
Goldman, R.D.5
Flitney, F.W.6
-
4
-
-
58149186945
-
Metastasis suppressors and the tumor microenvironment
-
Bodenstine TM, Welch DR. (2008). Metastasis suppressors and the tumor microenvironment. Cancer Microenviron 1: 1-11.
-
(2008)
Cancer Microenviron
, vol.1
, pp. 1-11
-
-
Bodenstine, T.M.1
Welch, D.R.2
-
5
-
-
0024402057
-
Expression of intermediate filament proteins in fetal and adult human lung tissues
-
Broers JL, de Leij L, Rot MK, ter Haar A, Lane EB, Leigh IM et al. (1989). Expression of intermediate filament proteins in fetal and adult human lung tissues. Differentiation 40: 119-128.
-
(1989)
Differentiation
, vol.40
, pp. 119-128
-
-
Broers, J.L.1
De Leij, L.2
Rot, M.K.3
Ter Haar, A.4
Lane, E.B.5
Leigh, I.M.6
-
6
-
-
0035020420
-
Caspase cleavage of vimentin disrupts intermediate filaments and promotes apoptosis
-
Byun Y, Chen F, Chang R, Trivedi M, Green KJ, Cryns VL. (2001). Caspase cleavage of vimentin disrupts intermediate filaments and promotes apoptosis. Cell Death Differ 8: 443-450.
-
(2001)
Cell Death Differ
, vol.8
, pp. 443-450
-
-
Byun, Y.1
Chen, F.2
Chang, R.3
Trivedi, M.4
Green, K.J.5
Cryns, V.L.6
-
8
-
-
0028004289
-
Mice lacking vimentin develop and reproduce without an obvious phenotype
-
DOI 10.1016/0092-8674(94)90553-3
-
Colucci-Guyon E, Portier MM, Dunia I, Paulin D, Pournin S, Babinet C. (1994). Mice lacking vimentin develop and reproduce without an obvious phenotype. Cell 79: 679-694. (Pubitemid 24363811)
-
(1994)
Cell
, vol.79
, Issue.4
, pp. 679-694
-
-
Colucci-Guyon, E.1
Portier, M.-M.2
Dunla, I.3
Paulin, D.4
Pournin, S.5
Babinet, C.6
-
9
-
-
0031850378
-
Impaired mechanical stability, migration and contractile capacity in vimentin-deficient fibroblasts
-
Eckes B, Dogic D, Colucci-Guyon E, Wang N, Maniotis A, Ingber D et al. (1998). Impaired mechanical stability, migration and contractile capacity in vimentin-deficient fibroblasts. J Cell Sci 111(Part 13): 1897-1907.
-
(1998)
J Cell Sci
, vol.111
, Issue.PART 13
, pp. 1897-1907
-
-
Eckes, B.1
Dogic, D.2
Colucci-Guyon, E.3
Wang, N.4
Maniotis, A.5
Ingber, D.6
-
10
-
-
34249661591
-
Phosphorylation of beta-catenin by AKT promotes betacatenin transcriptional activity
-
Fang D, Hawke D, Zheng Y, Xia Y, Meisenhelder J, Nika H et al. (2007). Phosphorylation of beta-catenin by AKT promotes betacatenin transcriptional activity. J Biol Chem 282: 11221-11229.
-
(2007)
J Biol Chem
, vol.282
, pp. 11221-11229
-
-
Fang, D.1
Hawke, D.2
Zheng, Y.3
Xia, Y.4
Meisenhelder, J.5
Nika, H.6
-
11
-
-
0032496146
-
Phosphorylation of vimentin by Rho-associated kinase at a unique amino-terminal site that is specifically phosphorylated during cytokinesis
-
Goto H, Kosako H, Tanabe K, Yanagida M, Sakurai M, Amano M et al. (1998). Phosphorylation of vimentin by Rho-associated kinase at a unique amino-terminal site that is specifically phosphorylated during cytokinesis. J Biol Chem 273: 11728-11736.
-
(1998)
J Biol Chem
, vol.273
, pp. 11728-11736
-
-
Goto, H.1
Kosako, H.2
Tanabe, K.3
Yanagida, M.4
Sakurai, M.5
Amano, M.6
-
12
-
-
0037728809
-
The protein kinase Akt induces epithelial mesenchymal transition and promotes enhanced motility and invasiveness of squamous cell carcinoma lines
-
Grille SJ, Bellacosa A, Upson J, Klein-Szanto AJ, van Roy F, Lee- Kwon W et al. (2003). The protein kinase Akt induces epithelial mesenchymal transition and promotes enhanced motility and invasiveness of squamous cell carcinoma lines. Cancer Res 63: 2172-2178.
-
(2003)
Cancer Res
, vol.63
, pp. 2172-2178
-
-
Grille, S.J.1
Bellacosa, A.2
Upson, J.3
Klein-Szanto, A.J.4
Van Roy, F.5
Lee-Kwon, W.6
-
13
-
-
29344452931
-
Protein kinase A phosphorylates and regulates dimerization of 14-3- 3 epsilon
-
Gu YM, Jin YH, Choi JK, Baek KH, Yeo CY, Lee KY. (2006). Protein kinase A phosphorylates and regulates dimerization of 14-3- 3 epsilon. FEBS Lett 580: 305-310.
-
(2006)
FEBS Lett
, vol.580
, pp. 305-310
-
-
Gu, Y.M.1
Jin, Y.H.2
Choi, J.K.3
Baek, K.H.4
Yeo, C.Y.5
Lee, K.Y.6
-
14
-
-
0031016323
-
Experimental co-expression of vimentin and keratin intermediate filaments in human breast cancer cells results in phenotypic interconversion and increased invasive behavior
-
Hendrix MJ, Seftor EA, Seftor RE, Trevor KT. (1997). Experimental co-expression of vimentin and keratin intermediate filaments in human breast cancer cells results in phenotypic interconversion and increased invasive behavior. Am J Pathol 150: 483-495.
-
(1997)
Am J Pathol
, vol.150
, pp. 483-495
-
-
Hendrix, M.J.1
Seftor, E.A.2
Seftor, R.E.3
Trevor, K.T.4
-
15
-
-
34250013899
-
The AKT-mTOR pathway plays a critical role in the development of leiomyosarcomas
-
Hernando E, Charytonowicz E, Dudas ME, Menendez S, Matushansky I, Mills J et al. (2007). The AKT-mTOR pathway plays a critical role in the development of leiomyosarcomas. Nat Med 13: 748-753.
-
(2007)
Nat Med
, vol.13
, pp. 748-753
-
-
Hernando, E.1
Charytonowicz, E.2
Dudas, M.E.3
Menendez, S.4
Matushansky, I.5
Mills, J.6
-
16
-
-
2342527930
-
Activation of Akt-1 (PKB-alpha) can accelerate ErbB-2-mediated mammary tumorigenesis but suppresses tumor invasion
-
Hutchinson JN, Jin J, Cardiff RD, Woodgett JR, Muller WJ. (2004). Activation of Akt-1 (PKB-alpha) can accelerate ErbB-2-mediated mammary tumorigenesis but suppresses tumor invasion. Cancer Res 64: 3171-3178.
-
(2004)
Cancer Res
, vol.64
, pp. 3171-3178
-
-
Hutchinson, J.N.1
Jin, J.2
Cardiff, R.D.3
Woodgett, J.R.4
Muller, W.J.5
-
17
-
-
29144488505
-
Distinct roles of Akt1 and Akt2 in regulating cell migration and epithelial-mesenchymal transition
-
Irie HY, Pearline RV, Grueneberg D, Hsia M, Ravichandran P, Kothari N et al. (2005). Distinct roles of Akt1 and Akt2 in regulating cell migration and epithelial-mesenchymal transition. J Cell Biol 171: 1023-1034.
-
(2005)
J Cell Biol
, vol.171
, pp. 1023-1034
-
-
Irie, H.Y.1
Pearline, R.V.2
Grueneberg, D.3
Hsia, M.4
Ravichandran, P.5
Kothari, N.6
-
18
-
-
27844444696
-
PKCepsilon-mediated phosphorylation of vimentin controls integrin recycling and motility
-
Ivaska J, Vuoriluoto K, Huovinen T, Izawa I, Inagaki M, Parker PJ. (2005). PKCepsilon-mediated phosphorylation of vimentin controls integrin recycling and motility. EMBO J 24: 3834-3845.
-
(2005)
EMBO J
, vol.24
, pp. 3834-3845
-
-
Ivaska, J.1
Vuoriluoto, K.2
Huovinen, T.3
Izawa, I.4
Inagaki, M.5
Parker, P.J.6
-
19
-
-
34249301918
-
Akt1 governs breast cancer progression in vivo
-
Ju X, Katiyar S, Wang C, Liu M, Jiao X, Li S et al. (2007). Akt1 governs breast cancer progression in vivo. Proc Natl Acad Sci USA 104: 7438-7443.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 7438-7443
-
-
Ju, X.1
Katiyar, S.2
Wang, C.3
Liu, M.4
Jiao, X.5
Li, S.6
-
20
-
-
1042289788
-
Fibroblast growth factor-2- mediated capillary morphogenesis of endothelial cells requires signals via Flt-1/vascular endothelial growth factor receptor-1: Possible involvement of c-Akt
-
Kanda S, Miyata Y, Kanetake H. (2004). Fibroblast growth factor-2- mediated capillary morphogenesis of endothelial cells requires signals via Flt-1/vascular endothelial growth factor receptor-1: possible involvement of c-Akt. J Biol Chem 279: 4007-4016.
-
(2004)
J Biol Chem
, vol.279
, pp. 4007-4016
-
-
Kanda, S.1
Miyata, Y.2
Kanetake, H.3
-
21
-
-
62149103291
-
Prognostic importance of epithelial-mesenchymal transitionrelated protein expression in gastric carcinoma
-
Kim MA, Lee HS, Lee HE, Kim JH, Yang HK, Kim WH. (2009). Prognostic importance of epithelial-mesenchymal transitionrelated protein expression in gastric carcinoma. Histopathology 54: 442-451.
-
(2009)
Histopathology
, vol.54
, pp. 442-451
-
-
Kim, M.A.1
Lee, H.S.2
Lee, H.E.3
Kim, J.H.4
Yang, H.K.5
Kim, W.H.6
-
22
-
-
33645213629
-
Mechanism of Akt1 inhibition of breast cancer cell invasion reveals a protumorigenic role for TSC2
-
Liu H, Radisky DC, Nelson CM, Zhang H, Fata JE, Roth RA et al. (2006). Mechanism of Akt1 inhibition of breast cancer cell invasion reveals a protumorigenic role for TSC2. Proc Natl Acad Sci USA 103: 4134-4139.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 4134-4139
-
-
Liu, H.1
Radisky, D.C.2
Nelson, C.M.3
Zhang, H.4
Fata, J.E.5
Roth, R.A.6
-
23
-
-
34748845043
-
Phosphorylation of human insulin receptor substrate-1 at Serine 629 plays a positive role in insulin signaling
-
Luo M, Langlais P, Yi Z, Lefort N, De Filippis EA, Hwang H et al. (2007). Phosphorylation of human insulin receptor substrate-1 at Serine 629 plays a positive role in insulin signaling. Endocrinology 148: 4895-4905.
-
(2007)
Endocrinology
, vol.148
, pp. 4895-4905
-
-
Luo, M.1
Langlais, P.2
Yi, Z.3
Lefort, N.4
De Filippis, E.A.5
Hwang, H.6
-
24
-
-
33846416534
-
Akt1 ablation inhibits, whereas Akt2 ablation accelerates, the development of mammary adenocarcinomas in mouse mammary tumor virus (MMTV)-ErbB2/neu and MMTV-polyoma middle T transgenic mice
-
Maroulakou IG, Oemler W, Naber SP, Tsichlis PN. (2007). Akt1 ablation inhibits, whereas Akt2 ablation accelerates, the development of mammary adenocarcinomas in mouse mammary tumor virus (MMTV)-ErbB2/neu and MMTV-polyoma middle T transgenic mice. Cancer Res 67: 167-177.
-
(2007)
Cancer Res
, vol.67
, pp. 167-177
-
-
Maroulakou, I.G.1
Oemler, W.2
Naber, S.P.3
Tsichlis, P.N.4
-
25
-
-
34250901825
-
Down-regulation of vimentin expression inhibits carcinoma cell migration and adhesion
-
McInroy L, Maatta A. (2007). Down-regulation of vimentin expression inhibits carcinoma cell migration and adhesion. Biochem Biophys Res Commun 360: 109-114.
-
(2007)
Biochem Biophys Res Commun
, vol.360
, pp. 109-114
-
-
McInroy, L.1
Maatta, A.2
-
26
-
-
0035882283
-
Inactivation of the glial fibrillary acidic protein gene, but not that of vimentin, improves neuronal survival and neurite growth by modifying adhesion molecule expression
-
Menet V, Gimenez y Ribotta M, Chauvet N, Drian MJ, Lannoy J, Colucci-Guyon E et al. (2001). Inactivation of the glial fibrillary acidic protein gene, but not that of vimentin, improves neuronal survival and neurite growth by modifying adhesion molecule expression. J Neurosci 21: 6147-6158.
-
(2001)
J Neurosci
, vol.21
, pp. 6147-6158
-
-
Menet, V.1
Gimenez, Y.2
Ribotta, M.3
Chauvet, N.4
Drian, M.J.5
Lannoy, J.6
Colucci-Guyon, E.7
-
27
-
-
35048900480
-
Requirement of Ca2+ influxand phosphatidylinositol 3-kinase-mediated m-calpain activity for shear stress-induced endothelial cell polarity
-
Miyazaki T, Honda K, Ohata H. (2007). Requirement of Ca2+ influxand phosphatidylinositol 3-kinase-mediated m-calpain activity for shear stress-induced endothelial cell polarity. Am J Physiol Cell Physiol 293: C1216-25.
-
(2007)
Am J Physiol Cell Physiol
, vol.293
-
-
Miyazaki, T.1
Honda, K.2
Ohata, H.3
-
28
-
-
0032803128
-
Changes in nuclear morphology during apoptosis correlate with vimentin cleavage by different caspases located either upstream or downstream of Bcl-2 action
-
Morishima N. (1999). Changes in nuclear morphology during apoptosis correlate with vimentin cleavage by different caspases located either upstream or downstream of Bcl-2 action. Genes Cells 4: 401-414.
-
(1999)
Genes Cells
, vol.4
, pp. 401-414
-
-
Morishima, N.1
-
29
-
-
0020965175
-
Proteolysis of vimentin and desmin by the Ca2+-activated proteinase specific for these intermediate filament proteins
-
Nelson WJ, Traub P. (1983). Proteolysis of vimentin and desmin by the Ca2+-activated proteinase specific for these intermediate filament proteins. Mol Cell Biol 3: 1146-1156.
-
(1983)
Mol Cell Biol
, vol.3
, pp. 1146-1156
-
-
Nelson, W.J.1
Traub, P.2
-
30
-
-
33746800144
-
Pathological angiogenesis is induced by sustained Akt signaling and inhibited by rapamycin
-
Phung TL, Ziv K, Dabydeen D, Eyiah-Mensah G, Riveros M, Perruzzi C et al. (2006). Pathological angiogenesis is induced by sustained Akt signaling and inhibited by rapamycin. Cancer Cell 10: 159-170.
-
(2006)
Cancer Cell
, vol.10
, pp. 159-170
-
-
Phung, T.L.1
Ziv, K.2
Dabydeen, D.3
Eyiah-Mensah, G.4
Riveros, M.5
Perruzzi, C.6
-
31
-
-
53749097748
-
Identification of phosphorylation-induced changes in vimentin intermediate filaments by site-directed spin labeling and electron paramagnetic resonance
-
Pittenger JT, Hess JF, Budamagunta MS, Voss JC, Fitzgerald PG. (2008). Identification of phosphorylation-induced changes in vimentin intermediate filaments by site-directed spin labeling and electron paramagnetic resonance. Biochemistry 47: 10863-10870.
-
(2008)
Biochemistry
, vol.47
, pp. 10863-10870
-
-
Pittenger, J.T.1
Hess, J.F.2
Budamagunta, M.S.3
Voss, J.C.4
Fitzgerald, P.G.5
-
32
-
-
33644865025
-
Evidence that Ser87 of BimEL is phosphorylated by Akt and regulates BimEL apoptotic function
-
Qi XJ, Wildey GM, Howe PH. (2006). Evidence that Ser87 of BimEL is phosphorylated by Akt and regulates BimEL apoptotic function. J Biol Chem 281: 813-823.
-
(2006)
J Biol Chem
, vol.281
, pp. 813-823
-
-
Qi, X.J.1
Wildey, G.M.2
Howe, P.H.3
-
33
-
-
0031770943
-
RhoA-binding kinase alpha translocation is facilitated by the collapse of the vimentin intermediate filament network
-
Sin WC, Chen XQ, Leung T, Lim L. (1998). RhoA-binding kinase alpha translocation is facilitated by the collapse of the vimentin intermediate filament network. Mol Cell Biol 18: 6325-6339.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 6325-6339
-
-
Sin, W.C.1
Chen, X.Q.2
Leung, T.3
Lim, L.4
-
34
-
-
0142011466
-
PTEN: From pathology to biology
-
Sulis ML, Parsons R. (2003). PTEN: from pathology to biology. Trends Cell Biol 13: 478-483.
-
(2003)
Trends Cell Biol
, vol.13
, pp. 478-483
-
-
Sulis, M.L.1
Parsons, R.2
-
35
-
-
0036173144
-
Akt1 and Akt2 differently regulate muscle creatine kinase and myogenin gene transcription in insulin-induced differentiation of C2C12 myoblasts
-
Sumitani S, Goya K, Testa JR, Kouhara H, Kasayama S. (2002). Akt1 and Akt2 differently regulate muscle creatine kinase and myogenin gene transcription in insulin-induced differentiation of C2C12 myoblasts. Endocrinology 143: 820-828.
-
(2002)
Endocrinology
, vol.143
, pp. 820-828
-
-
Sumitani, S.1
Goya, K.2
Testa, J.R.3
Kouhara, H.4
Kasayama, S.5
-
36
-
-
0035863411
-
AKT activation up-regulates insulin-like growth factor i receptor expression and promotes invasiveness of human pancreatic cancer cells
-
Tanno S, Tanno S, Mitsuuchi Y, Altomare DA, Xiao GH, Testa JR. (2001). AKT activation up-regulates insulin-like growth factor I receptor expression and promotes invasiveness of human pancreatic cancer cells. Cancer Res 61: 589-593.
-
(2001)
Cancer Res
, vol.61
, pp. 589-593
-
-
Tanno, S.1
Tanno, S.2
Mitsuuchi, Y.3
Altomare, D.A.4
Xiao, G.H.5
Testa, J.R.6
-
37
-
-
33744793989
-
Prognostic significance of activated AKT expression in soft-tissue sarcoma
-
Tomita Y, Morooka T, Hoshida Y, Zhang B, Qiu Y, Nakamichi I et al. (2006). Prognostic significance of activated AKT expression in soft-tissue sarcoma. Clin Cancer Res 12: 3070-3077.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 3070-3077
-
-
Tomita, Y.1
Morooka, T.2
Hoshida, Y.3
Zhang, B.4
Qiu, Y.5
Nakamichi, I.6
-
38
-
-
44449144396
-
Epithelial-mesenchymal transition: At the crossroads of development and tumor metastasis
-
Yang J, Weinberg RA. (2008). Epithelial-mesenchymal transition: at the crossroads of development and tumor metastasis. Dev Cell 14: 818-829.
-
(2008)
Dev Cell
, vol.14
, pp. 818-829
-
-
Yang, J.1
Weinberg, R.A.2
-
39
-
-
27944446105
-
Akt blocks breast cancer cell motility and invasion through the transcription factor NFAT
-
Yoeli-Lerner M, Yiu GK, Rabinovitz I, Erhardt P, Jauliac S, Toker A. (2005). Akt blocks breast cancer cell motility and invasion through the transcription factor NFAT. Mol Cell 20: 539-550.
-
(2005)
Mol Cell
, vol.20
, pp. 539-550
-
-
Yoeli-Lerner, M.1
Yiu, G.K.2
Rabinovitz, I.3
Erhardt, P.4
Jauliac, S.5
Toker, A.6
-
40
-
-
42349084115
-
Soft tissue sarcoma cells are highly sensitive to AKT blockade: A role for p53-independent up-regulation of GADD45 alpha
-
Zhu QS, Ren W, Korchin B, Lahat G, Dicker A, Lu Y et al. (2008). Soft tissue sarcoma cells are highly sensitive to AKT blockade: a role for p53-independent up-regulation of GADD45 alpha. Cancer Res 68: 2895-2903.
-
(2008)
Cancer Res
, vol.68
, pp. 2895-2903
-
-
Zhu, Q.S.1
Ren, W.2
Korchin, B.3
Lahat, G.4
Dicker, A.5
Lu, Y.6
|