Treatment of pituitarydependent cushings disease with the multireceptor ligand somatostatin analog pasireotide SOM230: A multicenter phase ii trial
Boscaro, M. et al. Treatment of pituitarydependent Cushings disease with the multireceptor ligand somatostatin analog pasireotide (SOM230): a multicenter, phase ii trial. J. Clin. Endocrinol. Metab. 94, 115-122 (2009).
Pasireotide SOM230 provides clinical benefit in patients with cushings disease: Results from a large 12-month randomized-dose double-blind phase iii study abstract
abstract OC-1.7
Colao, a. et al. Pasireotide (SOM230) provides clinical benefit in patients with Cushings disease: results from a large, 12-month, randomized-dose, double-blind, phase iii study [abstract]. 14th european neuroendocrine association Congress (abstract OC-1.7) (2010).
Pasireotide acromegaly study group pasireotide SOM230 demonstrates efficacy and safety in patients with acromegaly: A randomized multicenter phase ii trial
Petersenn, S. et al. Pasireotide acromegaly Study Group. Pasireotide (SOM230) demonstrates efficacy and safety in patients with acromegaly: a randomized, multicenter, phase ii trial. J. Clin. Endocrinol. Metab. 95, 2781-2789 (2010).
The dopamine-somatostatin chimeric compound BiM-23a760 exerts antiproliferative and cytotoxic effects in human non-functioning pituitary tumors by activating erK1/2 and p38 pathways
Peverelli, e. et al. The dopamine-somatostatin chimeric compound BiM-23a760 exerts antiproliferative and cytotoxic effects in human non-functioning pituitary tumors by activating erK1/2 and p38 pathways. Cancer Lett. 288, 170-176 (2010).
A phase ii exploratory study of BiM23a760 in acromegalic patients: Preliminary results of safety and efficacy after a single-dose administration abstract P3-673
Lesage, C. et al. a phase ii exploratory study of BiM23a760 in acromegalic patients: Preliminary results of safety and efficacy after a single-dose administration [abstract P3-673]. The endocrine Societys annual meeting (2009).
Temozolomide treatment in aggressive pituitary tumors and pituitary carcinomas: A french multicenter experience
raverot, G. et al. Temozolomide treatment in aggressive pituitary tumors and pituitary carcinomas: a French multicenter experience. J. Clin. Endocrinol. Metab. 95, 4592-4599 (2010).
Low O6-methylguanine-dna methyltransferase MGMT expression and response to temozolomide in aggressive pituitary tumours
Oxf
McCormack, a. i. et al. Low O6- methylguanine- Dna methyltransferase (MGMT) expression and response to temozolomide in aggressive pituitary tumours. Clin. Endocrinol. (Oxf.) 71, 226-233 (2009).
Temozolomide treatment for aggressive pituitary tumors: Correlation of clinical outcome with O6-methylguanine methyltransferase MGMT promoter methylation and expression
Bush, Z. M. et al. Temozolomide treatment for aggressive pituitary tumors: correlation of clinical outcome with O6-methylguanine methyltransferase (MGMT) promoter methylation and expression. J. Clin. Endocrinol. Metab. 95, e280-e290 (2010).