In vivo incorporation of fenfluramine and norfenfluramine into pigmented and nonpigmented hair of rats measured by HPLC-fluorescence detection

Forensic Toxicology

Volumn 29, Issue 1, 2011, Pages 44-50

  Kaddoumi, Amal ^a   Wada, Mitsuhiro ^a   Nakashima, Kenichiro ^a  

^a NAGASAKI UNIVERSITY   (Japan)

Author keywords

Fenfluramine; Hair analysis; Melanin; N Nitrosofenfluramine; Norfenfluramine; Zucker rats

Indexed keywords

FENFLURAMINE; NORFENFLURAMINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD LEVEL; CONTROLLED STUDY; FLUORESCENCE ANALYSIS; HAIR ANALYSIS; HAIR LEVEL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VIVO STUDY; MALE; NONHUMAN; PIGMENTATION; PRIORITY JOURNAL; RAT; WISTAR RAT; ZUCKER RAT;

RATTUS; RATTUS NORVEGICUS;

EID: 79251632864     PISSN: 18608965     EISSN: 18608973     Source Type: Journal    
DOI: 10.1007/s11419-010-0105-y     Document Type: Article

References (24)

1. SP Gygi DG Wilkins DE Rollins 1997 A comparison of phenobarbital and codeine incorporation into pigmented and nonpigmented rat hair J Pharm Sci 86 209 214 1:CAS:528:DyaK2sXmtVyhuw%3D%3D 10.1021/js960268h 9040097 (Pubitemid 27078386)
2. R Knonstrand J Ahlner N Dizdar G Larson 2003 Quantitative analysis of desmethylselegiline, methamphetamine, and amphetamine in hair and plasma from Parkinson patients on long-term selegiline medication J Anal Toxicol 27 135 141
3. DE Rollins DG Wilkins GG Krueger MP Augsburger A Mizuno C O'Neal CR Borges MH Slawson 2003 The effect of hair color on the incorporation of codeine into human hair J Anal Toxicol 27 545 551 1:CAS:528:DC%2BD3sXoslOjurc%3D 14670132
4. SP Gygi RE Joseph Jr EJ Cone DG Wilkins DE Rollins 1996 Incorporation of codeine and metabolites into hair. Role of pigmentation Drug Metab Dispos 24 495 501 1:CAS:528:DyaK28XisVWnur0%3D 8801066
5. CR Borges SD Martin LJ Meyer DG Wilkins DE Rollins 2002 Influx and efflux of amphetamine and N-acetylamphetamine in keratinocytes, pigmented melanocytes, and nonpigmented melanocytes J Pharm Sci 91 1523 1535 1:CAS:528: DC%2BD38XktlWrs7c%3D 10.1002/jps.10144 12115851 (Pubitemid 34633967)
6. K Kudo T Ishida W Hikiji Y Usumoto T Umehara K Nagamatsu A Tsuji N Ikeda 2010 Pattern of poisoning in Japan: selection of drugs and poisons for systematic toxicological analysis Forensic Toxicol 28 25 32 1:CAS:528: DC%2BC3cXhtleit7g%3D 10.1007/s11419-009-0088-8
7. JY Kim KS Jung MK Kim JI Lee MK In 2007 Simultaneous determination of psychotropic phenylalkylamine derivatives in human hair by gas chromatography/mass spectrometry Rapid Commun Mass Spectrom 21 1705 1720 1:CAS:528:DC%2BD2sXmt1Onu7s%3D 10.1002/rcm.3010 17474080 (Pubitemid 46827206)
8. H Miyaguchi YT Iwata T Kanamori K Tsujikawa K Kuwayama H Inoue 2009 Rapid identification and quantitation of methamphetamine and amphetamine in hair by gas chromatography/mass spectrometry coupled with micropulverized extraction, aqueous acetylation and microextraction by packed sorbent J Chromatogr A 1216 4063 4070 1:CAS:528:DC%2BD1MXkt1Sls7k%3D 10.1016/j.chroma.2009.02.093 19286186
9. S Nakamura M Wada BL Crabtree PM Reeves JH Montgomery HJ Byrd S Harada N Kuroda K Nakashima 2007 A sensitive semi-micro column HPLC method with peroxyoxalate chemiluminescence detection and column switching for determination of MDMA-related compounds in hair Anal Bioanal Chem 387 1983 1990 1:CAS:528:DC%2BD2sXisV2hsL0%3D 10.1007/s00216-006-0915-2 17093959 (Pubitemid 46355148)
10. P Kintz M Villain 2010 Violence under influence of methylphenidate as determined by hair analysis Forensic Toxicol 28 115 118 10.1007/s11419-010-0093- y
11. A Kaddoumi M Wada MN Nakashima K Nakashima 2004 Hair analysis for fenfluramine and norfenfluramine as biomarkers for N-nitrosofenfluramine ingestion Forensic Sci Int 146 39 46 1:CAS:528:DC%2BD2cXos12jurw%3D 10.1016/j.forsciint.2004.03.018 15485720 (Pubitemid 39370124)
12. A Kaddoumi MN Nakashima T Maki Y Matsumura J Nakamura K Nakashima 2003 HPLC studies on the pharmacokinetics of phentermine and fenfluramine in brain and blood microdialysates after intraperitoneal administration to rats J Chromatogr B 791 291 303 1:CAS:528:DC%2BD3sXkt1OrsrY%3D 10.1016/S1570-0232(03) 00231-9 (Pubitemid 36638762)
13. K Nakashima H Yamasaki N Kuroda S Akiyama 1995 Evaluation of lophine derivatives as chemiluminogens by a flow-injection method Anal Chim Acta 303 103 107 1:CAS:528:DyaK2MXjvVSqt7c%3D 10.1016/0003-2670(94)00360-X
14. Y Nakahara R Kikura K Takahashi 1998 Hair analysis for drugs of abuse XX. Incorporation and behaviors of seven methamphetamine homologs in the rat hair root Life Sci 63 883 893 1:CAS:528:DyaK1cXltlCnsr8%3D 10.1016/S0024-3205(98) 00345-2 9734708 (Pubitemid 28378327)
15. CR Borges JC Roberts DG Wilkins DE Rollins 2003 Cocaine, benzoylecgonine, amphetamine, and N-acetylamphetamine binding to melanin subtypes J Anal Toxicol 27 1 10
16. MA Huestis RA Gustafson ET Moolchan A Barnes JA Bourland SA Sweeney EF Hayes PM Carpenter ML Smith 2007 Cannabinoid concentrations in hair from documented cannabis users Forensic Sci Int 169 129 136 1:CAS:528: DC%2BD2sXmtVOlsbw%3D 10.1016/j.forsciint.2006.08.005 16963215 (Pubitemid 46829701)
17. G Skopp P Strohbeck-Kuehner K Mann D Hermann 2007 Deposition of cannabinoids in hair after long-term use of cannabis Forensic Sci Int 170 46 50 1:CAS:528:DC%2BD2sXntFyhsLk%3D 10.1016/j.forsciint.2006.09.003 17098389 (Pubitemid 46991190)
18. M Bresson M Villain V Cirimele P Kintz 2006 Doping control for metandienone using hair analyzed by gas chromatography-tandem mass spectrometry J Chromatogr B 836 124 128 1:CAS:528:DC%2BD28XksFaktr8%3D 10.1016/j.jchromb. 2006.03.040
19. MWF Nielen JJP Lasaroms PPJ Mulder JV Hende JA Rhijn MJ Groot 2006 Multi residue screening of intact testosterone esters and boldenone undecylenate in bovine hair using liquid chromatography electrospray tandem mass spectrometry J Chromatogr B 830 126 134 1:CAS:528:DC%2BD2MXhtlCrsLnP 10.1016/j.jchromb.2005.10. 028 (Pubitemid 41831398)
20. CR Borges DG Wilkins DE Rollins 2001 Amphetamine and N-acetylamphetamine incorporation into hair: an investigation of the potential role of drug basicity in hair color bias J Anal Toxicol 25 221 227 1:CAS:528:DC%2BD3MXjvFartrk%3D 11386634
21. RE Joseph Jr T Su EJ Cone 1996 In vitro binding studies to hair: influence of melanin and lipids on cocaine binding to Caucasoid and Africoid hair J Anal Toxicol 20 338 344 1:CAS:528:DyaK28XlvF2rtr8%3D 8889667
22. C Moore C Coulter K Crompton 2007 Determination of cocaine, benzoylecgonine, cocaethylene and norcocaine in human hair using solid-phase extraction and liquid chromatography with tandem mass spectrometric detection J Chromatogr B 859 208 212 1:CAS:528:DC%2BD2sXht12ns7vF 10.1016/j.jchromb.2007.09. 037 (Pubitemid 350046452)
23. S Hegstad HZ Khiabani L Kristoffersen N Kunoe PP Lobmaier AS Christophersen 2008 Drug screening of hair by liquid chromatography-tandem mass spectrometry J Anal Toxicol 32 364 372 1:CAS:528:DC%2BD1cXmvVGnt70%3D 18544222
24. RE Joseph Jr KM Höld DG Wilkins DE Rollins EJ Cone 1999 Drug testing with alternative matrices II. Mechanisms of cocaine and codeine deposition in hair J Anal Toxicol 23 396 408 1:CAS:528:DyaK1MXmsVyju7g%3D 10517543