Magnesium supplementation improves indicators of low magnesium status and inflammatory stress in adults older than 51 years with poor quality sleep

Magnesium Research

Volumn 23, Issue 4, 2010, Pages 158-168

  Nielsen, Forrest H ^a   Johnson, Luann K ^a   Zeng, Huawei ^a  

^a GRAND FORKS HUMAN NUTRITION RESEARCH CENTER   (United States)

Author keywords

Inflammatory stress; Magnesium deficiency; Magnesium intake; Magnesium supplementation; Sleep

Indexed keywords

MAGNESIUM;

AGED; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIET SUPPLEMENTATION; FEMALE; HUMAN; INFLAMMATION; MAGNESIUM DEFICIENCY; MALE; METABOLISM; MIDDLE AGED; PATHOPHYSIOLOGY; PHYSIOLOGICAL STRESS; RANDOMIZED CONTROLLED TRIAL; SLEEP DISORDER;

AGED; AGED, 80 AND OVER; DIETARY SUPPLEMENTS; FEMALE; HUMANS; INFLAMMATION; MAGNESIUM; MAGNESIUM DEFICIENCY; MALE; MIDDLE AGED; SLEEP DISORDERS; STRESS, PHYSIOLOGICAL;

ANIMALIA;

EID: 79251628365     PISSN: 09531424     EISSN: 19524021     Source Type: Journal    
DOI: 10.1684/mrh.2010.0220     Document Type: Article

References (32)

1. Kruse HD, Orent ER, McCollum EV. Studies on magnesium deficiency in animals. Symptomatology resulting from magnesium deprivation. J Biol Chem 1932; 96: 519-39.
2. Mazur A, Maier JAM, Rock E, Gueux E, Nowacki W, Rayssiguieer Y. Magnesium and the inflammatory response: potential physiopathological implications. Arch Biochem Biophys 2007; 458: 48-56.
3. Moshfegh A, Goldman J, Ahuja J, Rodes D, LaComb R. What we eat in America, NHANES 2005-2006: Usual intakes from food and water compared to 1997 Dietary Reference Intakes for vitamin D, calcium, phosphorus, and magnesium. US Department of Agriculture, Agricultural Research Service, 2009. Available at: http://www.ars.usda.gov/ba/bhnrc/fsrg. Accessed November 2009.
4. Food and Nutrition Board, Institute of Medicine. Magnesium. In: Dietary Reference Intakes for calcium, phosphorus, magnesium, vitamin D, and fluoride. Washington, DC: National Academy Press, 1997: 190-249.
5. Vormann J, Günther T, Höllriegl V, Schümann K. Pathobiochemical effects of graded magnesium deficiency in rats. Z Ernährungswiss 1998; 37 (Suppl. 1): 92-7.
6. Kramer JH, Mak IT, Phillips TM, Weglicki WB. Dietary magnesium intake influences circulating proinflammatory neuropeptide levels and loss of myocardial tolerance to postischemic stress. Exp Biol Med 2003; 228: 655-73.
7. Hegsted DM, Vitale JJ, McGrath H. The effect of low temperature and dietary calcium upon magnesium requirement. J Nutr 1956; 58: 175-88.
8. Chaudhary DP, Boparai RK, Bansal DD. Implications of oxidative stress in high sucrose low magnesium diet fed rats. Eur J Nutr 2007; 46: 383-90.
9. Adrian M, Chanut E, Laurant P, Gaume V, Berthelot A. A long-term moderate magnesium-deficient diet aggravates cardiovascular risks associated with aging and increases mortality in rats. J Hyperten 2008; 26: 44-52.
10. Simpson N, Dinges DF. Sleep and inflammation. Nutr Rev 2007; 65: S244-52.
11. King DE, Mainous III AG, Geesey ME, Woolson RF. Dietary magnesium and C-reactive protein levels. J Am Coll Nutr 2005; 24: 161-71.
12. Bo S, Durazzo M, Guidi S, Carello M, Sacerdote C, Silli B, Rosato R, Cassader M, Gentile L, Pagano G. Dietary magnesium and fiber intakes and inflammatory and metabolic indicators in middle-aged subjects from a population-based cohort. Am J Clin Nutr 2006; 84: 1062-9.
13. King DE, Mainous III AG, Geesey ME, Ellis T. Magnesium intake and serum C-reactive protein levels in children. Magnes Res 2007; 20: 32-6.
14. Song Y, Li TY, van Dam RM, Manson JE, Hu FB. Magnesium intake and plasma concentrations of markers systemic inflammation and endothelial dysfunction in women. Am J Clin Nutr 2007; 85: 1068-74.
15. Chacko SA, Song Y, Nathan L, Tinker L, De Boer IH, Tylavsky F, Wallace R, Liu S. Relations of dietary magnesium intake to biomarkers of inflammation and endothelial dysfunction in an ethnically diverse cohort of postmenopausal women. Diabetes Care 2010; 33: 304-10.
16. Held K, Antonijevic IA, Kunzel H, Uhr M, Wetter TC, Golly IC, Steiger A, Murck H. Oral Mg (2+) supplementation reverses age-related neuroendocrine and sleep EEG changes in humans. Pharmacopsychiatry 2002; 35: 135-43.
17. Popoviciu L, Delast-Popoviciu D, Delast-Popoviciu R, Bagathai I, Bicher G, Buksa C, Covaciu S, Szalay E. Parasommias (non-epileptic nocturnal episodic manifestations) in patients with magnesium deficiency. Rev Roum Neurol Psychiat 1990; 28: 19-24.
18. Hornyak M, Haas P, Veit J, Gann H, Riemann D. Magnesium treatment of primary alcohol-dependent patients during subacute withdrawal: an open pilot study with polysomnography. Alcohol Clin Exp Res 2004; 28: 1702-9.
19. Depoortere H, Francon D, Llopis J. Effects of a magnesium-deficient diet on sleep organization in rats. Neuropsychobiology 1993; 27: 237-45.
20. Dai Q, Shrubsole MJ, Ness RM, Schlundt D, Cai Q, Smalley WE, Li M, Shyr Y, Zheng W. The relation of magnesium and calcium intakes and a genetic polymorphism in the magnesium transporter to colorectal neoplasia risk. Am J Clin Nutr 2007; 86: 743-51.
21. International Longevity Center Workshop Report. Sleep, Health and Aging. New York, NY, International Longevity Center-USA; 2003: 25 pp.
22. Nutrient Data Laboratory. USDA Nutrient Database for Standard Reference, Release 20. U.S. Department of Agriculture, Agricultural Research Service 2007. Available at: http://www.ars.usda.gov/ba/bhnrc/ndl, accessed July 2009.
23. Buysse DJ, Reynolds III CF, Monk TH, Berman SR, Kupfer DJ. The Pittsburgh Sleep Quality Index: a new instrument for psychiatric practice and research. Psychiatric Res 1989; 28: 193-213.
24. Pearson TA, Mensah GA, Alexander RW, Anderson AL, Cannon 3rd RO, Criqui M, Fadl YY, Fortmann SP, Hony Y, Myers GL, Rifai N, Smith Jr SC, Taubert K, Tracy RP, Vinicor F. AHA/CDC scientific statement. Markers of inflammation and cardiovascular disease. Circulation 2003; 107: 499-511.
25. Meier-Ewert HK, Ridker PM, Rifai N, Regan MM, Price NJ, Dinges DF, Mullington JM. Effect of sleep loss on C-reactive protein, an inflammatory marker of cardiovascular risk. J Am Coll Card 2004; 43: 678-83.
26. Prinz PN, Bailey SL, Woods DL. Sleep impairments in healthy seniors: roles of stress, cortisol, and interlukin-1 beta. Chronobiol Int 2000; 17: 391-404.
27. Popoviciu L, Bagathai J, Buksa C, Delast-Popoviciu D, Bicher G, Delast-Popoviciu R, Covaciu S, Szalay E. Clinical and polysomnographic researches in patients with sleep disorders associated with magnesium deficiencies. In: Lasserre B, Durlach J, eds. Magnesium -a relevant ion. London: John Libbey, 1991: 353-65.
28. Osada N, Suzuki N, Nakayama M, Yokoyama Y, Yamamoto A, Oya M, Murabayashi T, Yamamoto M, Omiya K, Itoh H, Murayama M. Erythrocyte magnesium and prostaglandin dynamics in chronic sleep deprivation. Clin Cardiol 1997; 20: 265-8.
29. Rodríquez-Morán M, Guerrero-Romero F. Elevated concentrations of TNF-alpha are related to low serum magnesium levels in obese subjects. Magnes Res 2004; 17: 189-96.
30. Corica F, Allegra A, Ientile R, Buemi M. Magnesium concentrations in plasma, erythrocytes, and platelets in hypertensive and normotensive obese subjects. Am J Hypertens 1997; 10: 1311-3.
31. Lee S, Park HK, Son SP, Lee CW, Kim U, Kim HJ. Effects of oral magnesium supplementation on insulin sensitivity and blood pressure in normomagnesmic nondiabetic overweight Korean adults. Nutr Metab Cardiovasc Dis 2009; 19: 781-8.
32. Huerta MG, Roemmich JN, Kington ML, Bovbjerg V, Weltman AL, Holmes VF, Patrie JT, Rogol AD, Nadler JL. Magnesium deficiency is associated with insulin resistance in obese children. Diabetes Care 2005; 28: 1175-81.