Correlates of acute insulin resistance in the early phase of non-diabetic ST-elevation myocardial infarction

Diabetes and Vascular Disease Research

Volumn 8, Issue 1, 2011, Pages 35-42

  Lazzeri, Chiara ^a   Valente, Serafina ^a   Chiostri, Marco ^a   Picariello, Claudio ^a   Gensini, Gian Franco ^a  

^a CAREGGI UNIVERSITY HOSPITAL   (Italy)

Author keywords

Acute insulin resistance; acute phase; HOMA index; hyperglycaemia; STEMI

Indexed keywords

ALANINE AMINOTRANSFERASE; AMINO TERMINAL PRO BRAIN NATRIURETIC PEPTIDE; ASPARTATE AMINOTRANSFERASE; C REACTIVE PROTEIN; CREATINE KINASE MB; CREATININE; FIBRINOGEN; GAMMA GLUTAMYLTRANSFERASE; GLUCOSE; HEMOGLOBIN A1C; INSULIN; LACTIC ACID; THYROTROPIN; TROPONIN I;

ADULT; AGED; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BODY MASS; CORRELATION ANALYSIS; CREATININE BLOOD LEVEL; FEMALE; FIBRINOGEN BLOOD LEVEL; GAMMA GLUTAMYL TRANSFERASE BLOOD LEVEL; GLUCOSE BLOOD LEVEL; GLUCOSE METABOLISM; GLYCEMIC INDEX; HOMEOSTATIC MODEL ASSESSMENT INDEX; HUMAN; HUMAN CELL; HYPERGLYCEMIA; INFLAMMATION; INSULIN BLOOD LEVEL; INSULIN RELEASE; INSULIN RESISTANCE; LEUKOCYTE COUNT; MAJOR CLINICAL STUDY; MALE; MULTIPLE LINEAR REGRESSION ANALYSIS; OUTCOME ASSESSMENT; PERCUTANEOUS CORONARY INTERVENTION; ST SEGMENT ELEVATION MYOCARDIAL INFARCTION; THYROTROPIN BLOOD LEVEL;

AGED; ANGIOPLASTY, BALLOON, CORONARY; FEMALE; HUMANS; INSULIN; INSULIN RESISTANCE; LINEAR MODELS; MALE; MIDDLE AGED; MYOCARDIAL INFARCTION;

EID: 79251620638     PISSN: 14791641     EISSN: None     Source Type: Journal    
DOI: 10.1177/1479164110396744     Document Type: Article

References (42)

1. Opie LH Metabolic management of acute myocardial infarction comes to the fore and extends beyond control of hyperglycemia. Circulation 2008 ; 117: 2172-2177.
2. Lazzeri C., Tarquini R., Giunta F. and Gensini GF Glucose dysmetabolism and prognosis in critical illness. Intern Emerg Med 2009 ; 4: 147-156.
3. Oswald GA, Smith CC, Betteridge DJ, et al. Determinants and importance of stress hyperglycaemia in non-diabetic patients with myocardial infarction. Br Med J (Clin Res Ed) 1986 ; 293: 917-922.
4. Deedwania P., Kosiborod M., Barrett E., et al. American Heart Association Diabetes Committee of the Council on Nutrition, Physical Activity and Metabolism. Hyperglycemia and acute coronary syndrome: a scientific statement from the American Heart Association Diabetes Committee of the Council on Nutrition, Physical Activity, and Metabolism. Circulation 2008 ; 117: 1610-1619.
5. Kosiborod M., Rathore SS and Inzucchi SE Admission glucose and mortality in elderly patients hospitalized with acute myocardial infarction: implications for patients with and without recognized diabetes. Circulation 2005 ; 111: 3078-3086.
6. Kosiborod M., Inzucchi SE, Krumholz HM, et al. Glucometrics in patients hospitalized with acute myocardial infarction: defining the optimal outcomes-based measure of risk. Circulation 2008 ; 117: 1018-1027.
7. Kosiborod M., Inzucchi SE, Krumholz HM, et al. Glucose normalization and outcomes in patients with acute myocardial infarction. Arch Intern Med 2009 ; 169: 438-446.
8. Svensson AM, McGuire DK, Abrahamsson P., et al. Association between hyper- and hypoglycaemia and 2 year all-cause mortality risk in diabetic patients with acute coronary events. Eur Heart J 2005 ; 26: 1255-1261.
9. Goyal A., Mahaffey KW, Garg J., et al. Prognostic significance of the change in glucose level in the first 24 h after acute myocardial infarction: results from the CARDINAL study. Eur Heart J 2006 ; 27: 1289-1297.
10. Suleiman M., Hammerman H., Boulos M., et al. Fasting glucose is an important independent risk factor for 30-day mortality in patients with acute myocardial infarction: a prospective study. Circulation 2005 ; 111: 754-760.
11. Lazzeri C., Chiostri M., Sori A., Valente S. and Gensini GF Postprocedural hyperglycemia in ST elevation myocardial infarction submitted to percutaneous coronary intervention: a prognostic indicator and a marker of metabolic derangement. J Cardiovasc Med (Hagerstown) 2010 ; 11: 7-13.
12. Lazzeri C., Valente S., Chiostri M., Picariello C. and Gensini GF In-hospital peak glycemia and prognosis in STEMI patients without previously known diabetes. Eur J Cardiovasc Prev Rehabil 2010 ; 17: 419-23.
13. Nishio K., Shigemitsu M., Kusuyama T., et al. Insulin resistance in nondiabetic patients with acute myocardial infarction. Cardiovasc Revasc Med 2006 ; 7 (2). 54-60.
14. Wallander M., Bartnik M. and Efendic S. Beta cell dysfunction in patients with acute myocardial infarction but without previously known type 2 diabetes: a report from the GAMI study. Diabetologia 2005 ; 48: 2229-2235.
15. Lazzeri C., Sori A., Chiostri M., et al. Prognostic role of insulin resistance as assessed by homeostatic model assessment index in the acute phase of myocardial infarction in nondiabetic patients submitted to percutaneous coronary intervention. Eur J Anaesthesiol 2009 ; 26: 856-862.
16. Garcia RG, Rincon MY, Arenas WD, et al. Hyperinsulinemia is a predictor of new cardiovascular events in Colombian patients with a first myocardial infarction. Int J Cardiol 2009 (accessed 16 November 2009). [Epub ahead of print]
17. Valente S., Lazzeri C., Saletti E., Chiostri M. and Gensini GF Primary percutaneous coronary intervention in comatose survivors of cardiac arrest with ST-elevation acute myocardial infarction: a single-center experience in Florence. J Cardiovasc Med (Hagerstown) 2008 ; 9: 1083-1087.
18. Valente S., Lazzeri C., Chiostri M., et al. NT-proBNP on admission for early risk stratification in STEMI patients submitted to PCI. Relation with extension of STEMI and inflammatory markers. Int J Cardiol 2009 ; 132: 84-89.
19. Boden WE, O'Rourke RA, Teo KK, et al.; COURAGE Trial Research Group. Optimal medical therapy with or without PCI for stable coronary disease. N Engl J Med 2007 ; 356: 1503-1516.
20. Van de Werf F., Bax J., Betriu A., et al. Management of acute myocardial infarction in patients presenting with persistent ST-segment elevation: the Task Force on the Management of ST-Segment Elevation Acute Myocardial Infarction of the European Society of Cardiology. Eur Heart J 2008 ; 29: 2909-2945.
21. Levey, AS, Stevens LA, Schmid CH, et al. A new equation to estimate glomerular filtration rate. Ann Intern Med 2009 ; 150: 604-612.
22. Balkau B. and Charles M. for the European Group for the Study of Insulin Resistance (EGIR). Comment on the provisional report from the WHO Consultation. Diabet Med 1999 ; 16: 442-443.
23. Lazzeri C., Valente S., Chiostri M., Picariello C. and Gensini GF Acute glucose dysmetabolism in the early phase of ST-elevation myocardial infarction: the age response. Diab Vasc Dis Res 2010 ; 7: 131-7.
24. Allison SP, Prowse K. and Chamberlain MJ Failure of insulin response to glucose load during operation and after myocardial infarction. Lancet 1967 ; 1: 478-481.
25. Marquesvidal P., Sie P., Cambou JP, et al. Relationships of plasminogen-activator inhibitor activity and lipoprotein(a) with insulin, testosterone, 17b-estradiol, and testosterone binding globulin in myocardial-infarction patients. J Clin Endocrinol Metab 1995 ; 80: 1794-1798.
26. Stubbs PJ, Laycock J., Alaghband-Zadeh J., Carter G. and Noble MI Circulating stress hormone and insulin concentrations in acute coronary syndromes: identification of insulin resistance on admission. Clin Sci (Lond) 1999 ; 96: 589-595. (Pubitemid 29286587)
27. Matsui H., Hashimoto H., Fukushima A., et al. Fraction of cumulative creatine kinase correlates with insulin secretion in patients with acute myocardial infarction: insulin as a possible determinant of myocardial MB creatine kinase. Am Heart J 1996 ; 131: 24-31.
28. Gade W., Schmit J., Collins M., Gade J. Beyond obesity: the diagnosis and pathophysiology of metabolic syndrome. Clin Lab Sci 2010 ; 23: 51-61.
29. Dandona P., Chaudhuri A., Ghanim H. and Mohanty P. Pro-inflammatory effects of glucose and anti-inflammatory effect of insulin: relevance to cardiovascular disease. Am J Cardiol 2007 ; 99 (Suppl): 15B - 26B.
30. Dandona P., Chaudhuri A., Ghanim H., et al. Insulin as an anti-inflammatory and antiatherogenic modulator. J Am Coll Cardiol 2009 ; 53: S14 - S20.
31. Collier B., Dosset LA, May AK and Diaz JJ Glucose control and the inflammatory response. Nutr Clin Pract 2008 ; 23: 3-15.
32. Marfella R., Siniscalchi M., Esposito K., et al. Effects of stress hyperglycemia on acute myocardial infarction. Diabetes Care 2003 ; 26: 3129-3135.
33. Thomassen AR, Mortensen PT, Nielsen TT, et al. Altered plasma concentrations of glutamate, alanine and citrate in the early phase of acute myocardial infarction in man. Eur Heart J 2005 ; 7: 773-778.
34. Meier JJ, Deifuss S., Klamann A., et al. Plasma glucose at hospital admission and previous metabolic control determine myocardial infarct size and survival in patients with and without type 2 diabetes: the Langendreer Myocardial Infarction and Blood Glucose in Diabetic Patients Assessment (LAMBDA). Diabetes Care 2005 ; 28: 2551-2553.
35. Kosuge M., Kimura K., Kojima S., et al. Effects of glucose abnormalities on in-hospital outcome after coronary intervention for acute myocardial infarction. Circ J 2005 ; 69: 375-379.
36. Ishihara M., Kojima S., Sakamoto T., et al. Acute hyperglycemia is associated with adverse outcome after acute myocardial infarction in the coronary intervention era. Am Heart J 2005 ; 150: 814-820. (Pubitemid 41396520)
37. Cruz-Gonzales I., Chia S., Raffel OC, et al. Hyperglycemia on admission predicts larger infarct size in patients undergoing percutaneous coronary intervention for acute ST-elevation myocardial infarction. Diabetes Res Clin Pract 2010 ; 88: 97-102.
38. Kersten JR, Toller WG, Tessmer JP, et al. Hyperglycemia reduces coronary collateral blood flow through a nitric-oxide-mediated mechanism. Am J Physiol Heart Circ Physiol 2001 ; 281: H2097 - H2104.
39. Ceriello A., Quagliano L., D'Amico M., et al. Acute hyperglycemia induces nitrotyrosine formation and apoptosis in perfused heart from rat. Diabetes 2002 ; 51: 1076-1082.
40. Ceriello A., Zarich SW and Testa R. Lowering glucose to prevent adverse cardiovascular outcomes in a critical care setting. J Am Coll Cardiol 2009 ; 53: S9 - S13.
41. Morrow LA, Rosen SG and Halter JB Beta adrenergic regulation of insulin secretion: evidence of tissue heterogeneity of beta adrenergic responsiveness in the elderly. J Gerontol 1991 ; 46: M108 - M113.
42. Feldman RD, Limbird LE, Nadeau J., et al. Alterations in leukocyte β-receptor affinity with aging: a potential explanation for altered β-adrenergic sensitivity in the elderly. N Engl J Med 1984 ; 310: 815-819.