메뉴 건너뛰기




Volumn 21, Issue 3, 2011, Pages 274-281

Leptin reduces hyperactivity in an animal model for anorexia nervosa via the ventral tegmental area

Author keywords

Activity based anorexia; Anorexia nervosa; Hyperactivity; Leptin; Running wheel activity; Ventral tegmental area

Indexed keywords

LEPTIN;

EID: 79251614856     PISSN: 0924977X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.euroneuro.2010.11.006     Document Type: Article
Times cited : (57)

References (33)
  • 1
    • 0031436148 scopus 로고    scopus 로고
    • Divergent signaling capacities of the long and short isoforms of the leptin receptor
    • Bjorbaek C., Uotani S., da Silva B., Flier J.S. Divergent signaling capacities of the long and short isoforms of the leptin receptor. J. Biol. Chem. 1997, 272:32686-32695.
    • (1997) J. Biol. Chem. , vol.272 , pp. 32686-32695
    • Bjorbaek, C.1    Uotani, S.2    da Silva, B.3    Flier, J.S.4
  • 2
    • 34547849517 scopus 로고    scopus 로고
    • Chronic food restriction: enhancing effects on drug reward and striatal cell signaling
    • Carr K.D. Chronic food restriction: enhancing effects on drug reward and striatal cell signaling. Physiol. Behav. 2007, 91:459-472.
    • (2007) Physiol. Behav. , vol.91 , pp. 459-472
    • Carr, K.D.1
  • 4
    • 27644562839 scopus 로고    scopus 로고
    • Hypothalamic neuropeptide expression following chronic food restriction in sedentary and wheel-running rats
    • de Rijke C.E., Hillebrand J.J., Verhagen L.A., Roeling T.A., Adan R.A. Hypothalamic neuropeptide expression following chronic food restriction in sedentary and wheel-running rats. J. Mol. Endocrinol. 2005, 35:381-390.
    • (2005) J. Mol. Endocrinol. , vol.35 , pp. 381-390
    • de Rijke, C.E.1    Hillebrand, J.J.2    Verhagen, L.A.3    Roeling, T.A.4    Adan, R.A.5
  • 5
    • 0033082380 scopus 로고    scopus 로고
    • From lesions to leptin: hypothalamic control of food intake and body weight
    • Elmquist J.K., Elias C.F., Saper C.B. From lesions to leptin: hypothalamic control of food intake and body weight. Neuron 1999, 22:221-232.
    • (1999) Neuron , vol.22 , pp. 221-232
    • Elmquist, J.K.1    Elias, C.F.2    Saper, C.B.3
  • 6
    • 0033799526 scopus 로고    scopus 로고
    • Leptin suppresses semi-starvation induced hyperactivity in rats: implications for anorexia nervosa
    • Exner C., Hebebrand J., Remschmidt H., Wewetzer C., Ziegler A., Herpertz S., et al. Leptin suppresses semi-starvation induced hyperactivity in rats: implications for anorexia nervosa. Mol. Psychiatry 2000, 5:476-481.
    • (2000) Mol. Psychiatry , vol.5 , pp. 476-481
    • Exner, C.1    Hebebrand, J.2    Remschmidt, H.3    Wewetzer, C.4    Ziegler, A.5    Herpertz, S.6
  • 7
    • 0037458468 scopus 로고    scopus 로고
    • Expression of receptors for insulin and leptin in the ventral tegmental area/substantia nigra (VTA/SN) of the rat
    • Figlewicz D.P., Evans S.B., Murphy J., Hoen M., Baskin D.G. Expression of receptors for insulin and leptin in the ventral tegmental area/substantia nigra (VTA/SN) of the rat. Brain Res. 2003, 964:107-115.
    • (2003) Brain Res. , vol.964 , pp. 107-115
    • Figlewicz, D.P.1    Evans, S.B.2    Murphy, J.3    Hoen, M.4    Baskin, D.G.5
  • 9
    • 0034614698 scopus 로고    scopus 로고
    • Modulation of brain reward circuitry by leptin
    • Fulton S., Woodside B., Shizgal P. Modulation of brain reward circuitry by leptin. Science 2000, 287:125-128.
    • (2000) Science , vol.287 , pp. 125-128
    • Fulton, S.1    Woodside, B.2    Shizgal, P.3
  • 10
    • 0038043234 scopus 로고    scopus 로고
    • Hyperactivity in patients with anorexia nervosa and in semistarved rats: evidence for a pivotal role of hypoleptinemia
    • Hebebrand J., Exner C., Hebebrand K., Holtkamp C., Casper R.C., Remschmidt H., et al. Hyperactivity in patients with anorexia nervosa and in semistarved rats: evidence for a pivotal role of hypoleptinemia. Physiol. Behav. 2003, 79:25-37.
    • (2003) Physiol. Behav. , vol.79 , pp. 25-37
    • Hebebrand, J.1    Exner, C.2    Hebebrand, K.3    Holtkamp, C.4    Casper, R.C.5    Remschmidt, H.6
  • 11
    • 19544375637 scopus 로고    scopus 로고
    • Voluntary access to a warm plate reduces hyperactivity in activity-based anorexia
    • Hillebrand J.J., de Rijke C.E., Brakkee J.H., Kas M.J., Adan R.A. Voluntary access to a warm plate reduces hyperactivity in activity-based anorexia. Physiol. Behav. 2005, 85:151-157.
    • (2005) Physiol. Behav. , vol.85 , pp. 151-157
    • Hillebrand, J.J.1    de Rijke, C.E.2    Brakkee, J.H.3    Kas, M.J.4    Adan, R.A.5
  • 13
    • 4143131125 scopus 로고    scopus 로고
    • The contribution of anxiety and food restriction on physical activity levels in acute anorexia nervosa
    • Holtkamp K., Hebebrand J., Herpertz-Dahlmann B. The contribution of anxiety and food restriction on physical activity levels in acute anorexia nervosa. Int. J. Eat. Disord. 2004, 36:163-171.
    • (2004) Int. J. Eat. Disord. , vol.36 , pp. 163-171
    • Holtkamp, K.1    Hebebrand, J.2    Herpertz-Dahlmann, B.3
  • 14
    • 1942477406 scopus 로고    scopus 로고
    • High serum leptin levels subsequent to weight gain predict renewed weight loss in patients with anorexia nervosa
    • Holtkamp K., Hebebrand J., Mika C., Heer M., Heussen N., Herpertz-Dahlmann B. High serum leptin levels subsequent to weight gain predict renewed weight loss in patients with anorexia nervosa. Psychoneuroendocrinology 2004, 29:791-797.
    • (2004) Psychoneuroendocrinology , vol.29 , pp. 791-797
    • Holtkamp, K.1    Hebebrand, J.2    Mika, C.3    Heer, M.4    Heussen, N.5    Herpertz-Dahlmann, B.6
  • 16
    • 33748540764 scopus 로고    scopus 로고
    • Leptin receptor signaling in midbrain dopamine neurons regulates feeding
    • Hommel J.D., Trinko R., Sears R.M., Georgescu D., Liu Z.W., Gao X.B., et al. Leptin receptor signaling in midbrain dopamine neurons regulates feeding. Neuron 2006, 51:801-810.
    • (2006) Neuron , vol.51 , pp. 801-810
    • Hommel, J.D.1    Trinko, R.2    Sears, R.M.3    Georgescu, D.4    Liu, Z.W.5    Gao, X.B.6
  • 17
    • 33947139281 scopus 로고    scopus 로고
    • Ghrelin administration into tegmental areas stimulates locomotor activity and increases extracellular concentration of dopamine in the nucleus accumbens
    • Jerlhag E., Egecioglu E., Dickson S.L., Douhan A., Svensson L., Engel J.A. Ghrelin administration into tegmental areas stimulates locomotor activity and increases extracellular concentration of dopamine in the nucleus accumbens. Addict. Biol. 2007, 12:6-16.
    • (2007) Addict. Biol. , vol.12 , pp. 6-16
    • Jerlhag, E.1    Egecioglu, E.2    Dickson, S.L.3    Douhan, A.4    Svensson, L.5    Engel, J.A.6
  • 18
    • 0024022193 scopus 로고
    • Relative importance of calorie intake needed to gain weight and level of physical activity in anorexia nervosa
    • Kaye W.H., Gwirtsman H.E., Obarzanek E., George D.T. Relative importance of calorie intake needed to gain weight and level of physical activity in anorexia nervosa. Am. J. Clin. Nutr. 1988, 47:989-994.
    • (1988) Am. J. Clin. Nutr. , vol.47 , pp. 989-994
    • Kaye, W.H.1    Gwirtsman, H.E.2    Obarzanek, E.3    George, D.T.4
  • 19
    • 52949103300 scopus 로고    scopus 로고
    • AKT signaling within the ventral tegmental area regulates cellular and behavioral responses to stressful stimuli
    • Krishnan V., Han M.H., Mazei-Robison M., Iniguez S.D., Ables J.L., Vialou V., et al. AKT signaling within the ventral tegmental area regulates cellular and behavioral responses to stressful stimuli. Biol. Psychiatry 2008, 64:691-700.
    • (2008) Biol. Psychiatry , vol.64 , pp. 691-700
    • Krishnan, V.1    Han, M.H.2    Mazei-Robison, M.3    Iniguez, S.D.4    Ables, J.L.5    Vialou, V.6
  • 20
    • 37249065139 scopus 로고    scopus 로고
    • LRb signals act within a distributed network of leptin-responsive neurones to mediate leptin action
    • Leinninger G.M., Myers M.G. LRb signals act within a distributed network of leptin-responsive neurones to mediate leptin action. Acta Physiol Oxf 2008, 192:49-59.
    • (2008) Acta Physiol Oxf , vol.192 , pp. 49-59
    • Leinninger, G.M.1    Myers, M.G.2
  • 22
    • 43549114292 scopus 로고    scopus 로고
    • Mechanisms of leptin action and leptin resistance
    • Myers M.G., Cowley M.A., Munzberg H. Mechanisms of leptin action and leptin resistance. Annu. Rev. Physiol. 2008, 70:537-556.
    • (2008) Annu. Rev. Physiol. , vol.70 , pp. 537-556
    • Myers, M.G.1    Cowley, M.A.2    Munzberg, H.3
  • 23
    • 0037315042 scopus 로고    scopus 로고
    • Insulin activation of phosphatidylinositol 3-kinase in the hypothalamic arcuate nucleus: a key mediator of insulin-induced anorexia
    • Niswender K.D., Morrison C.D., Clegg D.J., Olson R., Baskin D.G., Myers M.G., et al. Insulin activation of phosphatidylinositol 3-kinase in the hypothalamic arcuate nucleus: a key mediator of insulin-induced anorexia. Diabetes 2003, 52:227-231.
    • (2003) Diabetes , vol.52 , pp. 227-231
    • Niswender, K.D.1    Morrison, C.D.2    Clegg, D.J.3    Olson, R.4    Baskin, D.G.5    Myers, M.G.6
  • 26
    • 0014177607 scopus 로고
    • Self-starvation of rats living in activity wheels on a restricted feeding schedule
    • Routtenberg A., Kuznesof A.W. Self-starvation of rats living in activity wheels on a restricted feeding schedule. J. Comp. Physiol. Psychol. 1967, 64:414-421.
    • (1967) J. Comp. Physiol. Psychol. , vol.64 , pp. 414-421
    • Routtenberg, A.1    Kuznesof, A.W.2
  • 27
    • 77950940201 scopus 로고    scopus 로고
    • Wheel running eliminates high-fat preference and enhances leptin signaling in the ventral tegmental area
    • Scarpace P.J., Matheny M., Zhang Y. Wheel running eliminates high-fat preference and enhances leptin signaling in the ventral tegmental area. Physiol. Behav. 2010, 100(2):173-179.
    • (2010) Physiol. Behav. , vol.100 , Issue.2 , pp. 173-179
    • Scarpace, P.J.1    Matheny, M.2    Zhang, Y.3
  • 29
    • 0035866247 scopus 로고    scopus 로고
    • Leptin attenuates acute food deprivation-induced relapse to heroin seeking
    • Shalev U., Yap J., Shaham Y. Leptin attenuates acute food deprivation-induced relapse to heroin seeking. J. Neurosci. 2001, 21:RC129.
    • (2001) J. Neurosci. , vol.21
    • Shalev, U.1    Yap, J.2    Shaham, Y.3
  • 30
    • 38149121526 scopus 로고    scopus 로고
    • Selective ablation of GABA neurons in the ventral tegmental area increases spontaneous locomotor activity
    • Shank E.J., Seitz P.K., Bubar M.J., Stutz S.J., Cunningham K.A. Selective ablation of GABA neurons in the ventral tegmental area increases spontaneous locomotor activity. Behav. Neurosci. 2007, 121:1224-1233.
    • (2007) Behav. Neurosci. , vol.121 , pp. 1224-1233
    • Shank, E.J.1    Seitz, P.K.2    Bubar, M.J.3    Stutz, S.J.4    Cunningham, K.A.5
  • 31
    • 57249108283 scopus 로고    scopus 로고
    • Bi-directional modulation of fast inhibitory synaptic transmission by leptin
    • Solovyova N., Moult P.R., Milojkovic B., Lambert J.J., Harvey J. Bi-directional modulation of fast inhibitory synaptic transmission by leptin. J. Neurochem. 2009, 108:190-201.
    • (2009) J. Neurochem. , vol.108 , pp. 190-201
    • Solovyova, N.1    Moult, P.R.2    Milojkovic, B.3    Lambert, J.J.4    Harvey, J.5
  • 32
    • 39749176352 scopus 로고    scopus 로고
    • Neuropeptidergic mediators of spontaneous physical activity and non-exercise activity thermogenesis
    • Teske J.A., Billington C.J., Kotz C.M. Neuropeptidergic mediators of spontaneous physical activity and non-exercise activity thermogenesis. Neuroendocrinology 2008, 87:71-90.
    • (2008) Neuroendocrinology , vol.87 , pp. 71-90
    • Teske, J.A.1    Billington, C.J.2    Kotz, C.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.