Protamine neutralisation of low molecular weight heparins and their oligosaccharide components

Analytical and Bioanalytical Chemistry

Volumn 399, Issue 2, 2011, Pages 763-771

  Schroeder, Mette ^a   Hogwood, John ^b   Gray, Elaine ^b   Mulloy, Barbara ^b   Hackett, Anne Marie ^b   Johansen, Kristian B ^a  

^a LEO PHARMA A S   (Denmark)

^b NATIONAL INSTITUTE FOR BIOLOGICAL STANDARDS AND CONTROL   (United Kingdom)

Author keywords

Anti Xa activity; Low molecular weight heparin; Neutralisation; Oligosaccharides; Protamine sulphate

Indexed keywords

ANTI-XA ACTIVITY; ANTICOAGULANT ACTIVITIES; LOW MOLECULAR WEIGHT; LOW-MOLECULAR WEIGHT HEPARINS; MOLECULAR BASIS; MONODISPERSE; NEUTRALISATION; SULPHATES; UNFRACTIONATED HEPARINS;

OLIGOSACCHARIDES; POLYSACCHARIDES;

MOLECULAR WEIGHT;

ANTICOAGULANT AGENT; BLOOD CLOTTING FACTOR 10A; DALTEPARIN; FACTOR IIA; HEPARIN ANTAGONIST; LOW MOLECULAR WEIGHT HEPARIN; OLIGOSACCHARIDE; PROTAMINE; PROTHROMBIN; TINZAPARIN;

ARTICLE; CHEMISTRY; DRUG ANTAGONISM; HUMAN; METABOLISM; MOLECULAR WEIGHT; PARTIAL THROMBOPLASTIN TIME;

ANTICOAGULANTS; DALTEPARIN; FACTOR XA; HEPARIN ANTAGONISTS; HEPARIN, LOW-MOLECULAR-WEIGHT; HUMANS; MOLECULAR WEIGHT; OLIGOSACCHARIDES; PARTIAL THROMBOPLASTIN TIME; PROTAMINES; PROTHROMBIN;

EID: 79251606517     PISSN: 16182642     EISSN: 16182650     Source Type: Journal    
DOI: 10.1007/s00216-010-4220-8     Document Type: Article

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