Activation of the EP4 prostanoid receptor induces prostaglandin E2 and pro-inflammatory cytokine production in human airway epithelial cells

Pulmonary Pharmacology and Therapeutics

Volumn 24, Issue 1, 2011, Pages 42-48

  Li, Tiesong ^a   Qi, Jiansong ^a   Cowley, Elizabeth A ^a  

^a DALHOUSIE UNIVERSITY   (Canada)

Author keywords

Airway epithelia; Calu 3 cell; Cytokine; EP4 receptor; Inflammation; Prostaglandin E2

Indexed keywords

19 HYDROXYPROSTAGLANDIN E1; CHEMOKINE; CYTOKINE; EARLY GROWTH RESPONSE FACTOR 1; EP4 PROSTANOID RECEPTOR; INTERLEUKIN 6; INTERLEUKIN 8; MISOPROSTOL; MITOGEN ACTIVATED PROTEIN KINASE; MONOCYTE CHEMOTACTIC PROTEIN 1; PROSTAGLANDIN E2; PROSTAGLANDIN RECEPTOR AFFECTING AGENT; PROSTANOID RECEPTOR; PROTEIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; CCL2 PROTEIN, HUMAN; EGR1 PROTEIN, HUMAN; PROSTAGLANDIN E RECEPTOR 4;

AIRWAY; ARTICLE; CELL ACTIVATION; CELL LINE; CELL SURFACE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; EPITHELIUM CELL; GENE EXPRESSION; HUMAN; HUMAN CELL; INFLAMMATORY CELL; POLYMERASE CHAIN REACTION; POSITIVE FEEDBACK; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; RECEPTOR AFFINITY; RESPIRATORY EPITHELIUM; TRANSCRIPTION INITIATION; BIOSYNTHESIS; CELL CULTURE; ENZYME ACTIVATION; METABOLISM; PHYSIOLOGY; TRACHEA;

CELLS, CULTURED; CHEMOKINE CCL2; CYTOKINES; DINOPROSTONE; EARLY GROWTH RESPONSE PROTEIN 1; ENZYME ACTIVATION; EPITHELIAL CELLS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HUMANS; INTERLEUKIN-6; INTERLEUKIN-8; RECEPTORS, PROSTAGLANDIN E, EP4 SUBTYPE; TRACHEA;

EID: 79251594735     PISSN: 10945539     EISSN: 15229629     Source Type: Journal    
DOI: 10.1016/j.pupt.2010.10.009     Document Type: Article

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