Intracranial microcapsule drug delivery device for the treatment of an experimental gliosarcoma model

Biomaterials

Volumn 32, Issue 10, 2011, Pages 2532-2539

  Scott, Alexander W ^a   Tyler, Betty M ^b   Masi, Byron C ^a   Upadhyay, Urvashi M ^c   Patta, Yoda R ^a   Grossman, Rachel ^b   Basaldella, Luca ^b   Langer, Robert S ^a,e   Brem, Henry ^d   Cima, Michael J ^a,e  

^a USA   (United States)

^b JOHNS HOPKINS HOSPITAL   (United States)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

^d Department of Biomedical Engineering ^*  (United States)

^e MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Drug delivery; Glioblastoma multiforme; Gliosarcoma; Intracranial; Microcapsule; Temozolomide

Indexed keywords

GLIOBLASTOMA MULTIFORME; GLIOSARCOMA; INTRACRANIAL; MICROCAPSULES; TEMOZOLOMIDE;

DRUG DOSAGE; ENCAPSULATION; EQUIPMENT; MASS TRANSFER; ORIFICES; PHYSICAL CHEMISTRY; TOXICITY; TUMORS;

CONTROLLED DRUG DELIVERY;

DNA; TEMOZOLOMIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOCOMPATIBILITY; CANCER SURVIVAL; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; DNA STRAND BREAKAGE; DRUG DELIVERY SYSTEM; DRUG DOSAGE FORM COMPARISON; DRUG EFFICACY; EXPERIMENTAL NEOPLASM; FEMALE; FLOW RATE; GLIOSARCOMA; IMMUNOHISTOCHEMISTRY; MICROCAPSULE; NONHUMAN; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; RAT; SURVIVAL TIME;

ANIMALS; BRAIN; BRAIN NEOPLASMS; CAPSULES; DACARBAZINE; DISEASE MODELS, ANIMAL; DRUG DELIVERY SYSTEMS; GLIOSARCOMA; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; KINETICS; RATS; RATS, INBRED F344;

ANIMALIA; RODENTIA;

EID: 79251593273     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2010.12.020     Document Type: Article

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