Transgenic expression of matrix metalloproteinase-2 induces coronary artery ectasia

International Journal of Experimental Pathology

Volumn 92, Issue 1, 2011, Pages 50-56

  Dahi, Sia ^a   Karliner, Joel S ^b   Sarkar, Rajabrata ^a   Lovett, David H ^b  

^a The Department of Surgery   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Aneurysm; Coronary artery ectasia; Elastin; Matrix metalloproteinase 2; Transgenic

Indexed keywords

ELASTIN; GELATINASE A;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY ANEURYSM; CORONARY ARTERY ATHEROSCLEROSIS; CORONARY ARTERY DILATATION; CORONARY ARTERY ECTASIA; FIBROSIS; GENETIC VARIABILITY; IMMUNOHISTOCHEMISTRY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; THREE DIMENSIONAL IMAGING; TRANSGENIC MOUSE;

ANIMALS; CORONARY ANEURYSM; CORONARY ARTERY DISEASE; CORONARY VESSELS; DILATATION, PATHOLOGIC; DISEASE MODELS, ANIMAL; MATRIX METALLOPROTEINASE 2; MICE; MICE, TRANSGENIC; MYOCARDIUM;

EID: 79251588042     PISSN: 09599673     EISSN: 13652613     Source Type: Journal    
DOI: 10.1111/j.1365-2613.2010.00744.x     Document Type: Article

References (24)

1. Alfonso-Jaume M.A., Bergman M.R., Mahimkar R. et al. (2006) Cardiac ischemia-reperfusion injury induces matrix metalloproteinase-2 expression through the AP-1 components FosB and JunB. Am. J. Physiol. Heart Circ. Physiol. 291, H1838-H1846.
2. Bergman M.R., Teerlink J.R., Mahimkar R. et al. (2007) Cardiac matrix metalloproteinase-2 expression independently induces marked ventricular remodeling and systolic dysfunction. Am. J. Physiol. Heart Circ. Physiol. 292, H1847-H1860.
3. Cai W.J., Kocsis E., Wu X. et al. (2004) Remodeling of the vascular tunica media is essential for development of collateral vessels in the canine heart. Mol. Cell. Biochem. 264, 201-210.
4. Davis V., Persidskaia R., Baca-Regen L. et al. (1998) Matrix metalloproteinase-2 production and its binding to the matrix are increased in abdominal aortic aneurysms. Arterioscler. Thromb. Vasc. Biol. 18, 1625-1633.
5. Finkelstein A., Michowitz Y., Abashidze A., Miller H., Keren G., George J. (2005) Temporal association between circulating proteolytic, inflammatory and neurohormonal markers in patients with coronary ectasia. Atherosclerosis 179, 353-359.
6. Freestone T., Turner R.J., Coady A., Higman D.J., Greenhalgh R.M., Powell J.T. (1995) Inflammation and matrix metalloproteinases in the enlarging abdominal aortic aneurysm. Arterioscler. Thromb. Vasc. Biol. 15, 1145-1151.
7. Goodall S., Crowther M., Hemingway D.M., Bell P.R., Thompson M.M. (2001) Ubiquitous elevation of matrix metalloproteinase-2 expression in the vasculature of patients with abdominal aneurysms. Circulation 104, 304-309.
8. Harendza S., Lovett D.H., Panzer U., Lukacs Z., Kuhno P., Stahl R.A. (2003) Linked common polymorphisms in the gelatinase A promoter are associated with diminished transcriptional response to estrogen and genetic fitness. J. Biol. Chem. 278, 20490-20499.
9. Lamblin N., Bauters C., Hermant X., Lablanche J.-M., Helbecque N., Amouyel P. (2002) Polymorphisms in the promoter regions of MMP-2, MMP-3, MMP-9 and MMP-12 genes as determinants of aneurysmal coronary artery disease. J. Am. Coll. Cardiol. 40, 43-48.
10. Li J.-J., Li Z., Li J. (2007) Is any link between inflammation and coronary artery ectasia? Med. Hypotheses 69, 678-683.
11. Longo G.M., Xiong W., Greiner T.C., Zhao Y., Fiotti N., Baxter B.T. (2002) Matrix metalloproteinases 2 and 9 work in concert to produce aortic aneurysms. J. Clin. Invest. 11, 625-632.
12. Manginas A. & Cokkino D.V. (2006) Coronary artery ectasias: imaging, functional assessment and clinical implications. Eur. Heart J. 27, 1026-1031.
13. Papadakis M., Leontiadis E., Manginas A. et al. (2004) Frequency of coronary artery ectasias in patients operated on for ascending aortic aneurysms. Am. J. Cardiol. 94, 1433-1435.
14. Raffetto J.D. & Khalil R.A. (2008) Matrix metalloproteinases and their inhibitors in vascular remodeling and vascular disease. Biochem. Pharmacol. 75, 346-359.
15. Ramappa P., Koitam A., Kuivanemi H., Thatai D. (2007) Coronary artery ectasia-is it time for a reappraisal? Clin. Cardiol. 30, 214-217.
16. Rath S., Har-Zahav Y., Battler A. et al. (1985) Fate of nonobstructive aneurysmatic coronary artery disease: angiographic and clinical follow-up report. Am. Heart J. 109, 785-791.
17. Sapadin A.N. & Fleischmajer R. (2006) Tetracyclines: nonantibiotic properties and their clinical implications. J. Am. Acad. Derm. 54, 258-265.
18. Stajduhar K.C., Laird J.R., Rogan K.M., Wortham D.C. (1993) Coronary arterial ectasia: increased prevalence in patients with abdominal aortic aneurysm as compared to occlusive atherosclerotic peripheral vascular disease. Am. Heart J. 125, 86-92.
19. Swaye P.S., Fisher L.D., Litwin P. et al. (1983) Aneurysmal coronary artery disease. Circulation 67, 134-138.
20. Thompson M. & Cockerill G. (2006) Matrix metalloproteinase-2: the forgotten enzyme in aneurysm pathogenesis. Ann. N.Y. Acad. Sci. 1085, 170-174.
21. Wang G.Y., Bergman M.R., Nguyen A.P. et al. (2006) Cardiac transgenic matrix metalloproteinase-expression directly induces impaired contractility. Cardiovasc. Res. 69, 688-696.
22. Yetkin E. & Waltenberger J. (2007) Novel insights into an old controversy. Is coronary artery ectasia a variant of coronary atherosclerosis? Clin. Res. Cardiol. 96, 331-339.
23. Zhou Y., Yu C., Miao X. et al. (2005) Functional haplotypes in the promoter of matrix metalloproteinase-2 and lung cancer susceptibility. Carcinogenesis 26, 1117-1121.
24. Zhou H.Z., Ma X., Gray M.O. et al. (2007) Transgenic MMP-2 expression induces latent cardiac mitochondrial dysfunction. Biochem. Biophys. Res. Commun. 358, 189-195.