Cardioprotective effects of luteolin during ischemia-reperfusion injury in rats

Circulation Journal

Volumn 75, Issue 2, 2011, Pages 443-450

  Liao, Pei Hu ^a   Hung, Li Man ^b   Chen, Yi Hung ^c   Kuan, Yu Hsiang ^a   Zhang, Friedrich Bo Yuan ^d   Lin, Ruey Hseng ^a   Shih, Hung Che ^a   Tsai, Shen Kou ^e   Huang, Shiang Suo ^a  

^a CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^b CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

^c CHINA MEDICAL UNIVERSITY   (Taiwan)

^d MACKAY MEMORIAL HOSPITAL   (Taiwan)

^e CHENG HSIN GENERAL HOSPITAL   (Taiwan)

Author keywords

Cardioprotective agent; Ischemia; Luteolin; Nitric oxide; Reperfusion

Indexed keywords

ENDOTHELIAL NITRIC OXIDE SYNTHASE; INDUCIBLE NITRIC OXIDE SYNTHASE; LACTATE DEHYDROGENASE; LUTEOLIN; MALONALDEHYDE; MESSENGER RNA; NEURONAL NITRIC OXIDE SYNTHASE; NITRIC OXIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIARRHYTHMIC ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; HEART INFARCTION; HEART INFARCTION SIZE; HEART MUSCLE ISCHEMIA; HEART PROTECTION; HEART VENTRICLE ARRHYTHMIA; HEART VENTRICLE FIBRILLATION; HEART VENTRICLE TACHYCARDIA; LACTATE DEHYDROGENASE BLOOD LEVEL; MALE; NONHUMAN; PROTEIN EXPRESSION; RAT; REPERFUSION INJURY;

ANIMALS; ANTI-ARRHYTHMIA AGENTS; ANTIOXIDANTS; CARDIOTONIC AGENTS; DRUG EVALUATION, PRECLINICAL; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HEMODYNAMICS; ISOENZYMES; L-LACTATE DEHYDROGENASE; LUTEOLIN; MALE; MYOCARDIAL INFARCTION; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; TACHYCARDIA, VENTRICULAR; VENTRICULAR FIBRILLATION;

EID: 79251557508     PISSN: 13469843     EISSN: 13474820     Source Type: Journal    
DOI: 10.1253/circj.CJ-10-0381     Document Type: Article

References (44)

1. Yasuda S, Shimokawa H. Acute myocardial infarction: The enduring challenge for cardiac protection and survival. Circ J 2009; 73: 2000-2008.
2. Mewton N, Ivanes F, Cour M, Ovize M. Postconditioning: From experimental proof to clinical concept. Dis Model Mech 2010; 3: 39-44.
3. Park JL, Lucchesi BR. Mechanisms of myocardial reperfusion injury. Ann Thorac Surg 1999; 68: 1905-1912.
4. Rosano GM, Fini M, Caminiti G, Barbaro G. Cardiac metabolism in myocardial ischemia. Curr Pharm Des 2008; 14: 2551-2562.
5. Werns SW, Lucchesi BR. Free radicals and ischemic tissue injury. Trends Pharmacol Sci 1990; 11: 161-166.
6. Gao FF, Hao SY, Huang ZQ, Zhang YM, Zhou YQ, Chen YC, et al. Cardiac electrophysiological and antiarrhythmic effects of N-nbutyl haloperidol iodide. Cell Physiol Biochem 2010; 25: 433-442.
7. Moens AL, Claeys MJ, Timmermans JP, Vrints CJ, Myocardial ischemia/reperfusion-injury: A clinical view on a complex pathophysiological process. Int J Cardiol 2005; 100: 179-190.
8. Myerburg RJ, Kessler KM, Mallon SM, Cox MM, deMarchena E, Interian A Jr, et al. Life-threatening ventricular arrhythmias in patients with silent myocardial ischemia due to coronary-artery spasm. N Engl J Med 1992; 326: 1451-1455.
9. Huang SS, Tsai SK, Chiang LY, Chih LH, Tsai MC. Cardioprotective effects of hexasulfobutylated C60 (FC4S) in anesthetized rats during coronary occlusion/reperfusion injury. Drug Develop Res 2001; 53: 244-253.
10. Jolly SR, Kane WJ, Bailie MB, Abrams GD, Lucchesi BR. Canine myocardial reperfusion injury: Its reduction by the combined administration of superoxide dismutase and catalase. Circ Res 1984; 54: 277-285.
11. Li L, Henry GE, Seeram NP. Identification and bioactivities of resveratrol oligomers and flavonoids from Carex folliculata seeds. J Agr Food Chem 2009; 57: 7282-7287.
12. Lin CN, Kuo SH, Chung MI, Ko FN, Teng CM. A new flavone Cglycoside and antiplatelet and vasorelaxing flavones from Gentiana arisanensis. J Nat Prod 1997; 60: 851-853.
13. Chang J, Hsu Y, Kuo P, Kuo Y, Chiang L, Lin C. Increase of Bax/ Bcl-XL ratio and arrest of cell cycle by luteolin in immortalized human hepatoma cell line. Life Sci 2005; 76: 1883-1893.
14. Li YC, Hung CF, Yeh FT, Lin JP, Chung JG. Luteolin-inhibited arylamine N-acetyltransferase activity and DNA-2-aminofluorene adduct in human and mouse leukemia cells. Food Chem Toxicol 2001; 39: 641-647.
15. Yee SB, Lee JH, Chung HY, Im KS, Bae SJ, Choi JS, et al. Inhibitory effects of luteolin isolated from Ixeris sonchifolia Hance on the proliferation of HepG2 human hepatocellular carcinoma cells. Arch Pharm Res 2003; 26: 151-156.
16. DiCarlo G, Mascolo N, Izzo AA, Capasso F. Flavonoids: Old and new aspects of a class of natural therapeutic drugs. Life Sci 1999; 65: 337-353.
17. Zarzuelo A, Jimenez I, Gamez MJ, Utrilla P, Fernadez I, Torres MI, et al. Effects of luteolin 5-O-beta-rutinoside in streptozotocininduced diabetic rats. Life Sci 1996; 58: 2311-2316.
18. Wu MJ, Weng CY, Ding HY, Wu PJ. Anti-inflammatory and antiviral effects of Glossogyne tenuifolia. Life Sci 2005; 76: 1135-1146.
19. Chen YT, Zheng RL, Jia ZJ, Ju Y. Flavonoids as superoxide scavengers and antioxidants. Free Radical Biol Med 1990; 9: 19-21.
20. Nagao A, Seki M, Kobayashi H. Inhibition of xanthine oxidase by flavonoids. Biosci Biotech Biochem 1999; 63: 1787-1790.
21. Horvathova K, Chalupa I, Sebova L, Tothova D, Vachalkova A. Protective effect of quercetin and luteolin in human melanoma HMB-2 cells. Mutat Res 2005; 565: 105-112.
22. Rump AF, Schussler M, Acar D, Cordes A, Theisohn M, Rosen R, et al. Functional and antiischemic effects of luteolin-7-glucoside in isolated rabbit hearts. Gen Pharmacol 1994; 25: 1137-1142.
23. Huang SS, Liu SM, Lin SM, Liao PH, Lin RH, Chen YC, et al. Antiarrhythmic effect of caffeic acid phenethyl ester (CAPE) on myocardial ischemia/reperfusion injury in rats. Clin Biochem 2005; 38: 943-947.
24. Smith EF 3rd, Griswold DE, Egan JW, Hillegass LM, Dimartino MJ. Reduction of myocardial damage and polymorphonuclear leukocyte accumulation following coronary artery occlusion and reperfusion by the thromboxane receptor antagonist BM 13.505. J Cardiovasc Pharm 1989; 13: 715-722.
25. Johnston KM, Macleod BA, Walker MJA. Responses to ligation of a coronary artery in conscious rats and the actions of antiarrhythmics. Can J Physiol Pharmacol 1983; 61: 1340-1353.
26. Hung LM, Chen JK, Huang SS, Lee RS, Sua MJ. Cardioprotective effect of resveratrol, a natural antioxidant derived from grapes. Cardiovasc Res 2000; 47: 549-555.
27. Walker MJ, Curtis MJ, Hearse DJ, Campbell RW, Janse MJ, Yellon DM, et al. The Lambeth Conventions: Guidelines for the study of arrhythmias in ischemia infarction, and reperfusion. Cardiovasc Res 1988; 22: 447-455.
28. Tsai SK, Lin SM, Huang CH, Hung WC, Chih CL, Huang SS. Effect of desflurane-induced preconditioning following ischemia- reperfusion on nitric oxide release in rabbits. Life Sci 2004; 76: 651-660.
29. 15N] in biological fluids. Anal Biochem 1982; 126: 131-138.
30. Hung LM, Su MJ, Chen JK. Resveratrol protects myocardial ischemia- reperfusion injury through both NO-dependent and NO-independent mechanisms. Free Radical Biol Med 2004; 36: 774-781.
31. Erdelmeier I, Gérard-Monnier D, Yadan JC, Chaudière J. Reactions of N-methyl-2-phenlindole with malondialdehyde and 4-hydroxyalkenals: Mechanistic aspects of the colorimetric assay of lipid peroxidation. Chem Res Toxicol 1998; 11: 1184-1194.
32. Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976; 72: 248.
33. Moncada S, Palmer RM, Higger EA. Nitric oxide: Physiology, pathology, and pharmacology. Pharmacol Rev 1991; 43: 109-142.
34. Park KH, Rubin LE, Gross SS, Levi R. Nitric oxide is a mediator of hypoxic coronary vasodilatation: Relation to adenosine and cyclooxygenase- derived metabolites. Circ Res 1992; 71: 992-1001.
35. Riddell DR, Owen JS. Nitric oxide and platelet aggregation. Vitam Horm 1999; 57: 25-48.
36. Secco DD, Paron JA, de Oliveira SH, Ferreira SH, Silva JS, Cunha Fde Q. Neutrophil migration in inflammation: Nitric oxide inhibits rolling, adhesion and induces apoptosis. Nitric Oxide 2003; 9: 153-164.
37. Wang P, Zweier JL. Measurement of nitric oxide and peroxynitrite generation in the postischemic heart: Evidence for peroxynitritemediated reperfusion injury. J Biol Chem 1996; 271: 29223-29230.
38. Ottaviano FG, Handy DE, Loscalzo J. Redox regulation in the extracellular environment. Circ J 2008; 72: 1-16.
39. Alderton WK, Cooper CE, Knowles RG. Nitric oxide synthases: Structure, function and inhibition. Biochem J 2001; 357: 593-615.
40. Huang SS, Wei FC, Hung LM. Ischemic preconditioning attenuates postischemic leukocyte-endothelial cell interactions: Role of nitric oxide and protein kinase C. Circ J 2006; 70: 1070-1075.
41. vanMeeteren ME, Hendriks JJ, Dijkstra CD, van Tol EA. Dietary compounds prevent oxidative damage and nitric oxide production by cells involved in demyelinating disease. Biochem Pharmacol 2004; 67: 967-975.
42. Heistad DD, Wakisaka Y, Miller J, Chu Y, Pena-Silva R. Novel aspects of oxidative stress in cardiovascular diseases. Circ J 2009; 73: 201-207.
43. Tsutsui H, Kinugawa S, Matsushima S. Oxidative stress and mitochondrial DNA damage in heart failure. Circ J 2008; 72(Suppl A): A-31-A-37.
44. Miura T, Miki T. GSK-3β, a therapeutic target for cardiomyocyte protection. Circ J 2009; 73: 1184-1192.