The role of eIF1 in translation initiation codon selection in Caenorhabditis elegans

Genetics

Volumn 186, Issue 4, 2010, Pages 1187-1195

  Maduzia, Lisa L ^a   Moreau, Anais ^a   Poullet, Nausicaa ^a   Chaffre, Sebastien ^a   Zhang, Yinhua ^a  

^a NEW ENGLAND BIOLABS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; INITIATION FACTOR 1;

ARTICLE; CAENORHABDITIS ELEGANS; CODON; GENE MUTATION; GENE STRUCTURE; GENETIC ANALYSIS; GENETIC CODE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA TRANSLATION; TRANSLATION INITIATION;

ANIMALS; CAENORHABDITIS ELEGANS; CODON, INITIATOR; EUKARYOTIC INITIATION FACTOR-1; GREEN FLUORESCENT PROTEINS; GROWTH; HOMOZYGOTE; MUTATION, MISSENSE; PROTEIN BIOSYNTHESIS;

ANIMALIA; CAENORHABDITIS ELEGANS; EUKARYOTA; SACCHAROMYCES CEREVISIAE;

EID: 79251555659     PISSN: 00166731     EISSN: 00166731     Source Type: Journal    
DOI: 10.1534/genetics.110.121541     Document Type: Article

References (25)

1. ALGIRE, M. A., D. MAAG and J. R. LORSCH, 2005 Pi release from eIF2, not GTP hydrolysis, is the step controlled by start-site selection during eukaryotic translation initiation. Mol. Cell 20: 251-262.
2. CASTILHO-VALAVICIUS, B., H. YOON and T. F. DONAHUE, 1990 Genetic characterization of the Saccharomyces cerevisiae translational initiation suppressors sui1, sui2 and SUI3 and their effects on HIS4 expression. Genetics 124: 483-495.
3. CHEUNG, Y. N., D. MAAG, S. F. MITCHELL, C. A. FEKETE, M. A. ALGIRE et al., 2007 Dissociation of eIF1 from the 40S ribosomal subunit is a key step in start codon selection in vivo. Genes Dev. 21: 1217-1230.
4. CIGAN, A. M., L. FENG and T. F. DONAHUE, 1988 tRNAi(met) functions in directing the scanning ribosome to the start site of translation. Science 242: 93-97.
5. CIGAN, A. M., E. K. PABICH, L. FENG and T. F. DONAHUE, 1989 Yeast translation initiation suppressor sui2 encodes the alpha subunit of eukaryotic initiation factor 2 and shares sequence identity with the human alpha subunit. Proc. Natl. Acad. Sci. USA 86: 2784-2788.
6. CUI, Y., J. D. DINMAN, T. G. KINZY and S. W. PELTZ, 1998 The Mof2/Sui1 protein is a general monitor of translational accuracy. Mol. Cell. Biol. 18: 1506-1516.
7. DONAHUE, T. F., A. M. CIGAN, E. K. PABICH and B. C. VALAVICIUS, 1988 Mutations at a Zn(II) finger motif in the yeast eIF-2 beta gene alter ribosomal start-site selection during the scanning process. Cell 54: 621-632.
8. FLETCHER, C. M., T. V. PESTOVA, C. U. HELLEN and G. WAGNER, 1999 Structure and interactions of the translation initiation factor eIF1. EMBO J. 18: 2631-2637.
9. HUANG, H. K., H. YOON, E. M. HANNIG and T. F. DONAHUE, 1997 GTP hydrolysis controls stringent selection of the AUG start codon during translation initiation in Saccharomyces cerevisiae. Genes Dev. 11: 2396-2413.
10. KOLITZ, S. E., J. E. TAKACS and J. R. LORSCH, 2009 Kinetic and thermodynamic analysis of the role of start codon/anticodon base pairing during eukaryotic translation initiation. RNA 15: 138-152.
11. KOZAK, M., 1978 How do eucaryotic ribosomes select initiation regions in messenger RNA? Cell 15: 1109-1123.
12. KOZAK, M., 1989 The scanning model for translation: an update. J. Cell Biol. 108: 229-241.
13. LOMAKIN, I. B., V. G. KOLUPAEVA, A. MARINTCHEV, G. WAGNER and T. V. PESTOVA, 2003 Position of eukaryotic initiation factor eIF1 on the 40S ribosomal subunit determined by directed hydroxyl radical probing. Genes Dev. 17: 2786-2797.
14. MAAG, D., C. A. FEKETE, Z. GRYCZYNSKI and J. R. LORSCH, 2005 A conformational change in the eukaryotic translation preinitiation complex and release of eIF1 signal recognition of the start codon. Mol. Cell 17: 265-275.
15. MELLO, C., and A. FIRE, 1995 DNA transformation. Methods Cell Biol. 48: 451-482.
16. PASSMORE, L. A., T. M. SCHMEING, D. MAAG, D. J. APPLEFIELD, M. G. ACKER et al., 2007 The eukaryotic translation initiation factors eIF1 and eIF1A induce an open conformation of the 40S ribosome. Mol. Cell 26: 41-50.
17. PEABODY, D. S., 1989 Translation initiation at non-AUG triplets in mammalian cells. J. Biol. Chem. 264: 5031-5035.
18. PESTOVA, T. V., S. I. BORUKHOV and C. U. HELLEN, 1998 Eukaryotic ribosomes require initiation factors 1 and 1A to locate initiation codons. Nature 394: 854-859.
19. PESTOVA, T. V., J. R. LORSCH and C. U. T. HELLEN, 2007 The mechanism of translation initiation in eukaryotes, pp. 87-128 in Translational Control in Biology and Medicine, edited by M. B. MATHEWS, N. SONENBERG and J. W. B. HERSHEY. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York.
20. REIBARKH, M., Y. YAMAMOTO, C. R. SINGH, F. DEL RIO, A. FAHMY et al., 2008 Eukaryotic initiation factor (eIF)1 carries two distinct eIF5-binding faces important for multifactor assembly and AUG selection. J. Biol. Chem. 283: 1094-1103.
21. SINGH, C. R., H. HE, M. II, Y. YAMAMOTO and K. ASANO, 2004 Efficient incorporation of eukaryotic initiation factor 1 into the multifactor complex is critical for formation of functional ribosomal preinitiation complexes in vivo. J. Biol. Chem. 279: 31910-31920.
22. VAN AUKEN, K., D. WEAVER, B. ROBERTSON, M. SUNDARAM, T. SALDI et al., 2002 Roles of the Homothorax/Meis/Prep homolog UNC-62 and the Exd/Pbx homologs CEH-20 and CEH-40 in C. elegans embryogenesis. Development 129: 5255-5268.
23. WOOD, W. B., 1988 The Nematode Caenorhabditis elegans. Cold Spring Harbor Laboratory.
24. YOON, H. J., and T. F. DONAHUE, 1992 The suil suppressor locus in Saccharomyces cerevisiae encodes a translation factor that functions during tRNA(iMet) recognition of the start codon. Mol. Cell Biol. 12: 248-260.
25. ZHANG, Y., and L. L. MADUZIA, 2010 Mutations in Caenorhabditis elegans eIF2b permit translation initiation from non-AUG start codons. Genetics 185: 141-152.