Extended-spectrum β-lactamases Klebsiella pneumoniae: Multimodal infection control program in intensive care units

Journal of Preventive Medicine and Hygiene

Volumn 51, Issue 3, 2010, Pages 110-115

  Prospero, E ^a   Barbadoro, Pamela ^a   Esposto, E ^a   Manso, E ^b   Martini, E ^c   Savini, S ^c   Scaccia, F ^a   Tantucci, L ^a   Pelaia, P ^b   D'Errico, M M ^a  

^a UNIVERSITÀ POLITECNICA DELLE MARCHE   (Italy)

^b Associated Hospitals   (Italy)

^c Hospital Hygiene Service   (Italy)

Author keywords

Drug resistance multiple bacterial; Infection control; Intensive care units

Indexed keywords

ALCOHOL; ANTIINFECTIVE AGENT; CEPHALOSPORIN; EXTENDED SPECTRUM BETA LACTAMASE; QUINOLINE DERIVED ANTIINFECTIVE AGENT; SOAP;

ADULT; AGED; ARTICLE; BACTERIAL COLONIZATION; BACTERIAL STRAIN; BACTERIUM CONTAMINATION; BACTERIUM ISOLATE; BACTERIUM ISOLATION; CONTROLLED STUDY; FEMALE; GENOTYPE; HAND WASHING; HEALTH CARE PERSONNEL; HEALTH CARE PLANNING; HOSPITAL INFECTION; HUMAN; INFECTION CONTROL; INTENSIVE CARE UNIT; KLEBSIELLA PNEUMONIAE INFECTION; MAJOR CLINICAL STUDY; MALE; PULSED FIELD GEL ELECTROPHORESIS;

BETA-LACTAMASES; CROSS INFECTION; DRUG RESISTANCE, MULTIPLE, BACTERIAL; ELECTROPHORESIS, GEL, PULSED-FIELD; HANDWASHING; HOSPITALS, TEACHING; HUMANS; INFECTION CONTROL; INFECTIOUS DISEASE TRANSMISSION, PROFESSIONAL-TO-PATIENT; INTENSIVE CARE UNITS; ITALY; KLEBSIELLA INFECTIONS; KLEBSIELLA PNEUMONIAE; MALE;

EID: 79251551967     PISSN: 11212233     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (29)

1. Paterson DL, Bonomo RA. Extended-spectrum β-lactamases: a clinical update. Clin Microbiol Rev 2005;18:657-86.
2. Filozov A, Visintainer P, Carbonaro C, et al. Epidemiology of an outbreak of antibiotic-resistant Klebsiella pneumoniae at a tertiary care medical center. Am J Infect Control 2009;37:723-8.
3. Casewell M, Phillips I. Hands as route of transmission for Klebsiella species. BMJ 1977;2:1315-7.
4. Kollef MH, Fraser VJ. Antibiotic resistance in the intensive care unit. Ann Intern Med 2001;134:298-314.
5. Siegel JD, Rhinehart E, Jackson M, et al. Healthcare Infection Control Practices Advisory Committee: Management of multidrug-resistant organisms in health care settings, 2006. Am J Infect Control 2007;35:S165-93.
6. Boyce J. It is time for action: improving hand hygiene in hospitals. Ann Intern Med 1999;130:153-5.
7. Pittet D, Hugonnet S, Harbarth S, et al. Effectiveness of a hospital-wide program to improve compliance with hand hygiene. Infection Control Program. Lancet 2000;356:1307-12.
8. Laurent C, Rodriguez-Villalobos H, Rost F, et al. Intensive care unit outbreak of extended-spectrum beta-lactamase-producing Klebsiella pneumoniae controlled by cohorting patients and reinforcing infection control measures. Infect Control Hosp Epidemiol 2008;29:517-24.
9. Horan TC, Andrus M, Dudeck MA. CDC/NHSN surveillance definition of health care associated infection and criteria for specific types of infections in the acute care setting. Am J Infect Control 2008;36:309-32.
10. Siegel JD, Rhinehart E, Jackson M, et al. Health Care Infection Control Practices Advisory Committee 2007 Guideline for Isolation Precautions: Preventing Transmission of Infectious Agents in Health Care Settings. Am J Infect Control 2007;35: S65-164.
11. th informational supplement. Wayne, PA: Clinical Laboratory Standards Institute 2007.
12. Mugnaioli C, Manso E, Rossolini GM. ESBL evolution in Italy: rapid regional spread of a multidrug-resistant Klebsiella pneumoniae strain producing CTX-M-15. 17th European Congress of Clinical Microbiology and Infectious Diseases, Abstract number: 1733-172, ICC, Munich, Germany, 31 March - 04 April 2007.
13. Mugnaioli C, Luzzaro F, De Luca F, et al. CTX-M-type extended-spectrum beta-lactamases in Italy: molecular epidemiology of an emerging countrywide problem. Antimicrob Agents Chemother 2006;50:2700-6.
14. Pallecchi L, Malossi M, Mantella A, et al. Detection of CTX-M-type beta-lactamase genes in fecal Escherichia coli isolates from healthy children in Bolivia and Peru. Antimicrob Agents Chemother 2004;48:4556-61.
15. rd ed. New York: Cold Spring Harbor Laboratory Press 2001.
16. Herud T, Nilsen RM, Svendheim K, et al. Association between use of hand hygiene products and rates of health care-associated infections in a large university hospital in Norway. Am J Infect Control 2009;37:311-7.
17. Tenover FC, Arbeit RD, Goering RV, et al. Interpreting chromosomal DNA Restriction patterns produced by pulsed-field gel electrophoresis: criteria for bacterial strain typing. J Clin Microbiol 1995;33:2233-9.
18. Tenover FC, Arbeit RD, Goering RV. How to select and interpret molecular strain typing methods for epidemiological studies of bacterial infections: a review for healthcare epidemiologists. Molecular Typing Working Group, Society for Healthcare Epidemiology of America. Infect Control Hosp Epidemiol 1997;18:426-39.
19. Boszczowski I, Nicoletti C, Puccini DM, et al. Outbreak of extended spectrum beta-lactamase producing Klebsiella pneumoniae infection in a neonatal intensive care unit related to onychomycosis in a health care worker. Ped Infect Dis Jour 2005;24:648-50.
20. Centers for Disease Control and Prevention (CDC). Guidance for control of infections with carbapenem-resistant or carbapenemase-producing Enterobacteriaceae in acute care facilities. MMWR 2009;58:256-60.
21. Ayan M, Kuzucu C, Durmaz R, et al. Analysis of three outbreaks due to Klebsiella species in a neonatal intensive care unit. Infect Control Hosp Epidemiol 2003;24:495-500.
22. Boyce JM, Havill NL, Kohan C, et al. Do infection control measures work for methicillin-resistant Staphylococcus aureus? Infect Control Hosp Epidemiol 2004;25:395-401.
23. Wisniewski MF, Kim S, Trick WE, et al. Effect of education on hand hygiene beliefs and practices: a 5-year program. Infect Control Hosp Epidemiol 2007;28:88-91.
24. Widmer AF, Conzelman M, Tomic M, et al. Introducing alcoholbased hand rub for hand hygiene: the critical need for training. Infect Control Hosp Epidemiol 2007;28:50-4.
25. Trick WE, Vernon MO, Welbel SF, et al. Multicenter intervention program to increase adherence to hand hygiene recommendations and glove use and to reduce the incidence of antimicrobial resistance. Infect Control Hosp Epidemiol 2007;28:42-9.
26. Gould DJ, Chudleigh J, Drey NS, et al. Measuring handwashing performance in health service audits and research studies. J Hosp Infect 2007;66:109-15.
27. Bryce EA, Scharf S, Walker M, et al. The infection control audit: the standardized audit as a tool for change. Am Jour Infect Control 2007;35:271-83.
28. Whitby M, McLaws ML, Slater K, et al. Three successful interventions in health care workers that improve compliance with hand hygiene: is sustained replication possible? Am J Infect Control 2008;36:349-55.
29. Doumit G, Gattellari M, Grimshaw J, et al. Local opinion leaders: effects on professional practice and health care outcomes. Cochrane Database of Syst Rev 2007;24(1):CD000125.