Organ-level histological and biomechanical responses from localized osteoarticular injury in the rabbit knee

Journal of Orthopaedic Research

Volumn 29, Issue 3, 2011, Pages 340-346

  Vaseenon, Tanawat ^a   Tochigi, Yuki ^a   Heiner, Anneliese D ^a,b   Goetz, Jessica E ^a,b   Baer, Thomas E ^a   Fredericks, Douglas C ^a   Martin, James A ^a,b   Rudert, M James ^a   Hillis, Stephen L ^c,d   Brown, Thomas D ^a,b   McKinley, Todd O ^a  

^a UNIVERSITY OF IOWA   (United States)

^b IA United States   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

^d UNIVERSITY OF IOWA   (United States)

Author keywords

cartilage histology; joint injury; osteoarthritis; osteochondral defect; rabbit knee

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CADAVER; CARTILAGE; CONTROLLED STUDY; EUTHANASIA; FEMUR; FEMUR CONDYLE; HISTOLOGY; JOINT LAXITY; JOINT STABILITY; KNEE; KNEE INJURY; MECHANICAL PROBE; NONHUMAN; OSTEOARTICULAR INJURY; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; RABBIT; SCORING SYSTEM; SHAM PROCEDURE; TIBIA; WEIGHT BEARING;

ANIMALS; BIOMECHANICS; CADAVER; CARTILAGE, ARTICULAR; DISEASE MODELS, ANIMAL; KNEE INJURIES; OSTEOARTHRITIS, KNEE; OSTEOCHONDRITIS; RABBITS; WEIGHT-BEARING;

EID: 79251544282     PISSN: 07360266     EISSN: 1554527X     Source Type: Journal    
DOI: 10.1002/jor.21259     Document Type: Article

References (27)

1. Buckwalter JA, Brown TD,. 2004. Joint injury, repair, and remodeling: roles in post-traumatic osteoarthritis. Clin Orthop Relat Res 423: 7-16.
2. Brown TD, Pope DF, Hale JE, et al. 1991. Effects of osteochondral defect size on cartilage contact stress. J Orthop Res 9: 559-567.
3. Koh JL, Wirsing K, Lautenschlager E, et al. 2004. The effect of graft height mismatch on contact pressure following osteochondral grafting: a biomechanical study. Am J Sports Med 32: 317-320.
4. McKinley TO, Tochigi Y, Rudert MJ, et al. 2008. The effect of incongruity and instability on contact stress directional gradients in human cadaveric ankles. Osteoarthritis Cartilage 16: 1363-1369.
5. McKinley TO, Tochigi Y, Rudert MJ, et al. 2008. Instability-associated changes in contact stress and contact stress rates near a step-off incongruity. J Bone Joint Surg Am 90: 375-383.
6. Mansour JM, Wentorf FA, Degoede KM,. 1998. In vivo kinematics of the rabbit knee in unstable models of osteoarthrosis. Ann Biomed Eng 26: 353-360.
7. Newton PO, Woo SL, MacKenna DA, et al. 1995. Immobilization of the knee joint alters the mechanical and ultrastructural properties of the rabbit anterior cruciate ligament. J Orthop Res 13: 191-200.
8. Heiner AD, Rudert MJ, McKinley TO, et al. 2007. In vivo measurement of translational stiffness of rabbit knees. J Biomech 40: 2313-2317.
9. Pritzker KP, Gay S, Jimenez SA, et al. 2006. Osteoarthritis cartilage histopathology: grading and staging. Osteoarthritis Cartilage 14: 13-29.
10. Mankin HJ, Dorfman H, Lippiello L, et al. 1971. Biochemical and metabolic abnormalities in articular cartilage from osteo-arthritic human hips. II. Correlation of morphology with biochemical and metabolic data. J Bone Joint Surg Am 53: 523-537.
11. Gushue DL, Houck J, Lerner AL,. 2005. Rabbit knee joint biomechanics: motion analysis and modeling of forces during hopping. J Orthop Res 23: 735-742.
12. Hooiveld M, Roosendaal G, Vianen M, et al. 2003. Blood-induced joint damage: longterm effects in vitro and in vivo. J Rheumatol 30: 339-344.
13. Hooiveld M, Roosendaal G, Wenting M, et al. 2003. Short-term exposure of cartilage to blood results in chondrocyte apoptosis. Am J Pathol 162: 943-951.
14. Furman BD, Strand J, Hembree WC, et al. 2007. Joint degeneration following closed intraarticular fracture in the mouse knee: a model of posttraumatic arthritis. J Orthop Res 25: 578-592.
15. Convery FR, Akeson WH, Keown GH,. 1972. The repair of large osteochondral defects. An experimental study in horses. Clin Orthop Relat Res 82: 253-262.
16. Lefkoe TP, Walsh WR, Anastasatos J, et al. 1995. Remodeling of articular step-offs. Is osteoarthrosis dependent on defect size? Clin Orthop Relat Res 314: 253-265.
17. Lefkoe TP, Trafton PG, Ehrlich MG, et al. 1993. An experimental model of femoral condylar defect leading to osteoarthrosis. J Orthop Trauma 7: 458-467.
18. Braman JP, Bruckner JD, Clark JM, et al. 2005. Articular cartilage adjacent to experimental defects is subject to atypical strains. Clin Orthop Relat Res 430: 202-207.
19. Chen CT, Burton-Wurster N, Lust G, et al. 1999. Compositional and metabolic changes in damaged cartilage are peak-stress, stress-rate, and loading-duration dependent. J Orthop Res 17: 870-879.
20. Lee DA, Bader DL,. 1997. Compressive strains at physiological frequencies influence the metabolism of chondrocytes seeded in agarose. J Orthop Res 15: 181-188.
21. Morel V, Quinn TM,. 2004. Cartilage injury by ramp compression near the gel diffusion rate. J Orthop Res 22: 145-151.
22. Sah RL, Kim YJ, Doong JY, et al. 1989. Biosynthetic response of cartilage explants to dynamic compression. J Orthop Res 7: 619-636.
23. Andriacchi TP, Koo S, Scanlan SF,. 2009. Gait mechanics influence healthy cartilage morphology and osteoarthritis of the knee. J Bone Joint Surg Am 91: 95-101.
24. Kumar D, Fung W, Moore RM, et al. 2006. Proinflammatory cytokines found in amniotic fluid induce collagen remodeling, apoptosis, and biophysical weakening of cultured human fetal membranes. Biol Reprod 74: 29-34.
25. Qi J, Fox AM, Alexopoulos LG, et al. 2006. IL-1beta decreases the elastic modulus of human tenocytes. J Appl Physiol 101: 189-195.
26. Custers RJ, Creemers LB, van Rijen MH, et al. 2009. Cartilage damage caused by metal implants applied for the treatment of established localized cartilage defects in a rabbit model. J Orthop Res 27: 84-90.
27. Saris DB, Dhert WJ, Verbout AJ,. 2003. Joint homeostasis. The discrepancy between old and fresh defects in cartilage repair. J Bone Joint Surg Br 85: 1067-1076.