Ischaemia-reperfusion injury in orthotopic mouse lung transplants - a scanning electron microscopy study

International Journal of Experimental Pathology

Volumn 92, Issue 1, 2011, Pages 18-25

  Draenert, Alice ^a   Marquardt, Klaus ^a   Inci, Ilhan ^a   Soltermann, Alex ^a   Weder, Walter ^a   Jungraithmayr, Wolfgang ^a  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

Author keywords

Ischaemia reperfusion injury; Orthotopic mouse lung transplantation; Scanning electron microscopy

Indexed keywords

INTERCELLULAR ADHESION MOLECULE 1; LUNG SURFACTANT;

AIRWAY; ANIMAL TISSUE; ARTICLE; COLD ISCHEMIA; CONTROLLED STUDY; EXOCYTOSIS; GRAFT FAILURE; HISTOLOGY; IMMUNOHISTOCHEMISTRY; ISCHEMIA; LEUKOCYTE; LUNG ALVEOLUS CELL; LUNG BLOOD VESSEL; LUNG ENDOTHELIUM; LUNG TRANSPLANTATION; MICROVILLUS; MOUSE; MUCUS SECRETION; NONHUMAN; ORTHOTOPIC TRANSPLANTATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; REPERFUSION INJURY; SCANNING ELECTRON MICROSCOPY;

ANIMALS; IMMUNOHISTOCHEMISTRY; INTERCELLULAR ADHESION MOLECULE-1; LUNG; LUNG TRANSPLANTATION; MICE; MICE, INBRED C57BL; MICROSCOPY, ELECTRON, SCANNING; REPERFUSION INJURY;

EID: 79251539245     PISSN: 09599673     EISSN: 13652613     Source Type: Journal    
DOI: 10.1111/j.1365-2613.2010.00752.x     Document Type: Article

References (18)

1. Bachofen H., Ammann A., Wangensteen D., Weibel E.R. (1982) Perfusion fixation of lungs for structure-function analysis: credits and limitations. J. Appl. Physiol. 53, 528-533.
2. Bastacky J. & Goerke J. (1992) Pores of Kohn are filled in normal lungs: low-temperature scanning electron microscopy. J. Appl. Physiol. 73, 88-95.
3. Dobbs L.G., Johnson M.D., Vanderbilt J., Allen L., Gonzalez R. (2010) The great big alveolar TI cell: evolving concepts and paradigms. Cell Physiol. Biochem. 25, 55-62.
4. Eppinger M.J., Jones M.L., Deeb G.M., Bolling S.F., Ward P.A. (1995) Pattern of injury and the role of neutrophils in reperfusion injury of rat lung. J. Surg. Res. 58, 713-718.
5. Eppinger M.J., Deeb G.M., Bolling S.F., Ward P.A. (1997) Mediators of ischemia-reperfusion injury of rat lung. Am. J. Pathol. 150, 1773-1784.
6. Fehrenbach H., Schepelmann D., Albes J.M. et al. (1999) Pulmonary ischemia/reperfusion injury: a quantitative study of structure and function in isolated heart-lungs of the rat. Anat. Rec. 255, 84-89.
7. Graf R., Schiesser M., Lussi A., Went P., Scheele G.A., Bimmler D. (2002) Coordinate regulation of secretory stress proteins (PSP/reg, PAP I, PAP II, and PAP III) in the rat exocrine pancreas during experimental acute pancreatitis. J. Surg. Res. 105, 136-144.
8. Hasaniya N.W., Premaratne S., Zhang W.W. et al. (2009) Ischemia-reperfusion injury in the lung: quantitation using electron microscopy. Vasc. Endovascular Surg. 43, 170-177.
9. Hsia C.C., Hyde D.M., Ochs M., Weibel E.R. (2010) An official research policy statement of the American Thoracic Society/European Respiratory Society: standards for quantitative assessment of lung structure. Am. J. Respir. Crit. Care Med. 181, 394-418.
10. Inci I., Ampollini L., Arni S. et al. (2008) Ex vivo reconditioning of marginal donor lungs injured by acid aspiration. J. Heart Lung Transplant. 27, 1229-1236.
11. Jungraithmayr W.M., Korom S., Hillinger S., Weder W. (2009) A mouse model of orthotopic, single-lung transplantation. J. Thorac. Cardiovasc. Surg. 137, 486-491.
12. Lee J.C. & Christie J.D. (2009) Primary graft dysfunction. Proc. Am. Thorac. Soc. 6, 39-46.
13. Muhlfeld C., Schaefer I.M., Becker L. et al. (2009) Pre-ischaemic exogenous surfactant reduces pulmonary injury in rat ischaemia/reperfusion. Eur. Respir. J. 33, 625-633.
14. Okazaki M., Krupnick A.S., Kornfeld C.G. et al. (2007) A mouse model of orthotopic vascularized aerated lung transplantation. Am. J. Transplant. 7, 1672-1679.
15. Ovechkin A.V., Lominadze D., Sedoris K.C., Robinson T.W., Tyagi S.C., Roberts A.M. (2007) Lung ischemia-reperfusion injury: implications of oxidative stress and platelet-arteriolar wall interactions. Arch. Physiol. Biochem. 113, 1-12.
16. Premaratne S., Razzuk A.M., Hasaniya N.W. et al. (2000) Scanning electron microscopic changes in the morphology of rabbit pulmonary tissue biopsied following ischemia and reperfusion: a window of opportunity? J. Electron. Microsc. (Tokyo) 49, 675-679.
17. Putman E., van Golde L.M., Haagsman H.P. (1997) Toxic oxidant species and their impact on the pulmonary surfactant system. Lung 175, 75-103.
18. Zanotti G., Casiraghi M., Abano J.B. et al. (2009) Novel critical role of Toll-like receptor 4 in lung ischemia-reperfusion injury and edema. Am. J. Physiol. Lung Cell. Mol. Physiol. 297, L52-L63.