Hepatitis C virus (HCV) evades NKG2D-dependent NK cell responses through NS5A-mediated imbalance of inflammatory cytokines

PLoS Pathogens

Volumn 6, Issue 11, 2010, Pages

  Séne, Damien ^a,b,c   Levasseur, Franck ^a,b   Abel, Michal ^a,b   Lambert, Marion ^a,b   Camous, Xavier ^d   Hernandez, Cé line ^b   Péne, Véronique ^b   Rosenberg, Arielle R ^b   Jouvin Marche, Evelyne ^d   Marche, Patrice N ^d   Cacoub, Patrice ^c,e   Caillat Zucman, Sophie ^a,b  

^a HÔPITAL SAINT VINCENT DE PAUL   (France)

^b UNIVERSITÉ PARIS DESCARTES   (France)

^c PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^d INSERM   (France)

^e SORBONNE UNIVERSITÉ   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ENDOTOXIN; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 15; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MITOGEN ACTIVATED PROTEIN KINASE P38; MITOGEN ACTIVATED PROTEIN KINASE P38 INHIBITOR; NATURAL KILLER CELL RECEPTOR NKG2D; NONSTRUCTURAL PROTEIN 5A; PHOSPHATIDYLINOSITOL 3 KINASE; RECOMBINANT TRANSFORMING GROWTH FACTOR BETA; TOLL LIKE RECEPTOR 4; TRANSFORMING GROWTH FACTOR BETA; AUTACOID; CYTOKINE; NATURAL KILLER CELL LECTIN LIKE RECEPTOR SUBFAMILY K; NS 5 PROTEIN, HEPATITIS C VIRUS; NS-5 PROTEIN, HEPATITIS C VIRUS; VIRUS PROTEIN;

ADULT; AGED; AMINO ACID SEQUENCE; ARTICLE; CELL STIMULATION; CELLULAR IMMUNITY; CHRONICITY; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOTOXICITY; DOWN REGULATION; EFFECTOR CELL; FEMALE; HEPATITIS C; HEPATITIS C VIRUS; HUMAN; HUMAN CELL; IMMUNOMODULATION; INTERFERON PRODUCTION; LIVER BIOPSY; LIVER CELL; LYMPHOCYTE FUNCTION; MALE; MONOCYTE; NATURAL KILLER CELL; NONHUMAN; PROTEIN EXPRESSION; PROTEIN SYNTHESIS INHIBITION; SECRETORY PATHWAY; SUPERNATANT; VIRUS ENTRY; CYTOLOGY; FLOW CYTOMETRY; IMMUNOLOGY; LIVER CIRRHOSIS; METABOLISM; MIDDLE AGED; PATHOLOGY; VIRUS REPLICATION;

HEPATITIS C VIRUS;

ADULT; AGED; CYTOKINES; CYTOTOXICITY, IMMUNOLOGIC; FEMALE; FLOW CYTOMETRY; HEPACIVIRUS; HEPATITIS C, CHRONIC; HUMANS; IMMUNITY, CELLULAR; INFLAMMATION MEDIATORS; KILLER CELLS, NATURAL; LIVER CIRRHOSIS; MALE; MIDDLE AGED; MONOCYTES; NK CELL LECTIN-LIKE RECEPTOR SUBFAMILY K; VIRAL NONSTRUCTURAL PROTEINS; VIRUS REPLICATION; YOUNG ADULT;

EID: 79251522151     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1001184     Document Type: Article

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