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Volumn 41, Issue 2, 2011, Pages 118-125

Characterization of elevated alanine aminotransferase levels during pegylated-interferon α-2b plus ribavirin treatment for chronic hepatitis C

Author keywords

Abnormal ALT values; BMI; Drug involvement; Pegylated interferon 2b; Ribavirin

Indexed keywords

ALANINE AMINOTRANSFERASE; PEGINTERFERON ALPHA2A; PEGINTERFERON ALPHA2A PLUS RIBAVIRIN; PEGINTERFERON ALPHA2B; PEGINTERFERON ALPHA2B PLUS RIBAVIRIN; RIBAVIRIN; VIRUS RNA;

EID: 79251507671     PISSN: 13866346     EISSN: 1872034X     Source Type: Journal    
DOI: 10.1111/j.1872-034X.2010.00749.x     Document Type: Article
Times cited : (10)

References (23)
  • 1
    • 33644547392 scopus 로고    scopus 로고
    • Antiviral therapy for chronic hepatitis C: past, present, and future
    • Hayashi N, Takehara T. Antiviral therapy for chronic hepatitis C: past, present, and future. J Gastroenterol 2006; 41: 17-27.
    • (2006) J Gastroenterol , vol.41 , pp. 17-27
    • Hayashi, N.1    Takehara, T.2
  • 2
    • 26444472427 scopus 로고    scopus 로고
    • Prevention of hepatocellular carcinoma and its recurrence in chronic hepatitis C patients by interferon therapy
    • Omata M, Yoshida H, Shiratori Y. Prevention of hepatocellular carcinoma and its recurrence in chronic hepatitis C patients by interferon therapy. Clin Gastroenterol Hepatol 2005; 10 (Suppl 2): S141-3.
    • (2005) Clin Gastroenterol Hepatol , vol.10 , Issue.2 SUPPL.
    • Omata, M.1    Yoshida, H.2    Shiratori, Y.3
  • 3
    • 55749109703 scopus 로고    scopus 로고
    • Interferon-based therapy for chronic hepatitis C: current and future perspectives
    • Zeuzem S. Interferon-based therapy for chronic hepatitis C: current and future perspectives. Nat Clin Pract Gastroenterol Hepatol 2008; 5: 610-22.
    • (2008) Nat Clin Pract Gastroenterol Hepatol , vol.5 , pp. 610-22
    • Zeuzem, S.1
  • 4
    • 35448974936 scopus 로고    scopus 로고
    • Antiviral therapy: chronic hepatitis C
    • Heathcote EJ. Antiviral therapy: chronic hepatitis C. J Viral Hepat 2007; 14 (Suppl 1): 82-8.
    • (2007) J Viral Hepat , vol.14 , Issue.1 SUPPL. , pp. 82-8
    • Heathcote, E.J.1
  • 5
    • 0030842328 scopus 로고    scopus 로고
    • Acute hepatitis induced by interferon, associated with viral clearance, in chronic viral hepatitis
    • Cervoni J-P, Degos F, Marcellin P, Erlinger S. Acute hepatitis induced by interferon, associated with viral clearance, in chronic viral hepatitis. J Hepatol 1997; 27: 1113-16.
    • (1997) J Hepatol , vol.27 , pp. 1113-16
    • Cervoni, J.-P.1    Degos, F.2    Marcellin, P.3    Erlinger, S.4
  • 6
    • 34548479023 scopus 로고    scopus 로고
    • Fulminant hepatic failure in a case of autoimmune hepatitis in hepatitis C during peg-interferon-alpha 2b plus ribavirin treatment
    • Kogure T, Ueno Y, Fukushima K etal. Fulminant hepatic failure in a case of autoimmune hepatitis in hepatitis C during peg-interferon-alpha 2b plus ribavirin treatment. World J Gastroenterol 2007; 13: 4394-7.
    • (2007) World J Gastroenterol , vol.13 , pp. 4394-7
    • Kogure, T.1    Ueno, Y.2    Fukushima, K.3
  • 7
    • 0038174635 scopus 로고    scopus 로고
    • Type C-chronic hepatitis patients who had autoimmune phenomenon and developed jaundice during interferon therapy
    • Sezaki H, Arase Y, Tsubota A etal. Type C-chronic hepatitis patients who had autoimmune phenomenon and developed jaundice during interferon therapy. J Gastroenterol 2003; 38: 493-500.
    • (2003) J Gastroenterol , vol.38 , pp. 493-500
    • Sezaki, H.1    Arase, Y.2    Tsubota, A.3
  • 8
    • 0030886005 scopus 로고    scopus 로고
    • Side effects of alpha interferon in chronic hepatitis
    • Dusheiko G. Side effects of alpha interferon in chronic hepatitis. Hepatology 1997; 26 (Suppl 1): 112S-21S.
    • (1997) Hepatology , vol.26 , Issue.1 SUPPL.
    • Dusheiko, G.1
  • 9
    • 34248531497 scopus 로고    scopus 로고
    • Incidence and characterization of serum transaminases elevations in pegylated interferon and ribavirin treated patients with chronic hepatitis C
    • Thurairajah PH, Thorburn D, Hubsher S etal. Incidence and characterization of serum transaminases elevations in pegylated interferon and ribavirin treated patients with chronic hepatitis C. Aliment Phamacol Ther 2007; 25: 1293-300.
    • (2007) Aliment Phamacol Ther , vol.25 , pp. 1293-300
    • Thurairajah, P.H.1    Thorburn, D.2    Hubsher, S.3
  • 10
    • 66149099243 scopus 로고    scopus 로고
    • Elevations in alanine aminotransferase levels late in the course of anti-viral therapy in hepatitis C virus RNA-negative patients are associated with virological relapse
    • Basso M, Edoardo G, Torre F, Blanchi S, Savarino V, Picciotto A. Elevations in alanine aminotransferase levels late in the course of anti-viral therapy in hepatitis C virus RNA-negative patients are associated with virological relapse. Hepatology 2009; 49: 1442-8.
    • (2009) Hepatology , vol.49 , pp. 1442-8
    • Basso, M.1    Edoardo, G.2    Torre, F.3    Blanchi, S.4    Savarino, V.5    Picciotto, A.6
  • 11
    • 20044374023 scopus 로고    scopus 로고
    • Design and validation of a histological scoring system for nonalcoholic fatty liver disease
    • Kleiner DE, Brunt EM, Natta MV etal. Design and validation of a histological scoring system for nonalcoholic fatty liver disease. Hepatology 2005; 41: 1313-21.
    • (2005) Hepatology , vol.41 , pp. 1313-21
    • Kleiner, D.E.1    Brunt, E.M.2    Natta, M.V.3
  • 12
    • 0036434344 scopus 로고    scopus 로고
    • Is delayed normalization of alanine aminotransferase a poor prognostic predictor in chronic hepatitis C patients treated with a combined interferon and ribavirin therapy?
    • Hung CH, Lee CM, Lu SN etal. Is delayed normalization of alanine aminotransferase a poor prognostic predictor in chronic hepatitis C patients treated with a combined interferon and ribavirin therapy? J Gastroentarol Hepatol 2002; 17: 1307-11.
    • (2002) J Gastroentarol Hepatol , vol.17 , pp. 1307-11
    • Hung, C.H.1    Lee, C.M.2    Lu, S.N.3
  • 13
    • 0034619946 scopus 로고    scopus 로고
    • Peginterferon alpha-2a in patients with chronic hepatitis C
    • Zeuzem S, Feinman SV, Rasenack J etal. Peginterferon alpha-2a in patients with chronic hepatitis C. N Engl J Med 2000; 343: 1666-72.
    • (2000) N Engl J Med , vol.343 , pp. 1666-72
    • Zeuzem, S.1    Feinman, S.V.2    Rasenack, J.3
  • 14
    • 0043037223 scopus 로고    scopus 로고
    • High body mass index is an independent risk factor for nonresponse to antiviral treatment in chronic hepatitis C
    • Bressler BL, Guindi M, Tomlinson G, Heathcoate J. High body mass index is an independent risk factor for nonresponse to antiviral treatment in chronic hepatitis C. Hepatology 2003; 38: 639-44.
    • (2003) Hepatology , vol.38 , pp. 639-44
    • Bressler, B.L.1    Guindi, M.2    Tomlinson, G.3    Heathcoate, J.4
  • 15
    • 33847332205 scopus 로고    scopus 로고
    • Being overweight influences the development of hepatic dysfunction in Japanese patients with non-small-cell lung cancer undergoing cytotoxic chemotherapy
    • Fujiwara Y, Kiura K, Hotta K, Tabata M, Takikawa N, Tanimoto M. Being overweight influences the development of hepatic dysfunction in Japanese patients with non-small-cell lung cancer undergoing cytotoxic chemotherapy. Lung Cancer 2007; 55: 343-8.
    • (2007) Lung Cancer , vol.55 , pp. 343-8
    • Fujiwara, Y.1    Kiura, K.2    Hotta, K.3    Tabata, M.4    Takikawa, N.5    Tanimoto, M.6
  • 17
    • 0024367984 scopus 로고
    • Prolongation of isosfamide elimination half-life in obese patients due to altered drug distribution
    • Lind MJ, Margison JM, Cerny T, Thacher N, Wilkinson PM. Prolongation of isosfamide elimination half-life in obese patients due to altered drug distribution. Cancer Chemother Pharmacol 1989; 25: 139-42.
    • (1989) Cancer Chemother Pharmacol , vol.25 , pp. 139-42
    • Lind, M.J.1    Margison, J.M.2    Cerny, T.3    Thacher, N.4    Wilkinson, P.M.5
  • 18
    • 0033800745 scopus 로고    scopus 로고
    • Effects of obesity on pharmacokinetics implications for drug therapy
    • Cheymol G. Effects of obesity on pharmacokinetics implications for drug therapy. Clin Phamacokinet 2000; 39: 215-31.
    • (2000) Clin Phamacokinet , vol.39 , pp. 215-31
    • Cheymol, G.1
  • 19
    • 19444385812 scopus 로고    scopus 로고
    • Metabolic aspects of hepatitis C virus infection: steatohepatitis resembling but distinct from NASH
    • Koike K, Moriya K. Metabolic aspects of hepatitis C virus infection: steatohepatitis resembling but distinct from NASH. J Gastroenterol 2005; 40: 329-36.
    • (2005) J Gastroenterol , vol.40 , pp. 329-36
    • Koike, K.1    Moriya, K.2
  • 20
    • 46249111657 scopus 로고    scopus 로고
    • Hepatitis C virus infection: molecular pathways to metabolic syndrome
    • Sheikh MY, Choi J, Qadri I, Friedman JE, Sanyal AJ. Hepatitis C virus infection: molecular pathways to metabolic syndrome. Hepatology 2008; 47: 2127-33.
    • (2008) Hepatology , vol.47 , pp. 2127-33
    • Sheikh, M.Y.1    Choi, J.2    Qadri, I.3    Friedman, J.E.4    Sanyal, A.J.5
  • 21
    • 0003745736 scopus 로고    scopus 로고
    • Liver Biopsy Interpretation
    • 7th edn. Burlington: Elsevier Saunders, -
    • Scheuer JP, Lefkowitch JH. Liver Biopsy Interpretation, 7th edn. Burlington: Elsevier Saunders, 2006; 125-44.
    • (2006) , pp. 125-44
    • Scheuer, J.P.1    Lefkowitch, J.H.2
  • 22
    • 44949137249 scopus 로고    scopus 로고
    • Elevated serum ALT levels during pegylated interferon monotherapy may be caused by iron overload
    • Nagashima M, Kudo M, Chung H etal. Elevated serum ALT levels during pegylated interferon monotherapy may be caused by iron overload. Intervirology 2008; 51 (Suppl 1): S76-85.
    • (2008) Intervirology , vol.51 , Issue.1 SUPPL.
    • Nagashima, M.1    Kudo, M.2    Chung, H.3
  • 23
    • 33845938292 scopus 로고    scopus 로고
    • Pegylated proteins: evaluation of their safety in the absence of definitive metabolism studies
    • Webster R, Didier E, Harris P etal. Pegylated proteins: evaluation of their safety in the absence of definitive metabolism studies. Drug Metab Dispos 2007; 35: 9-16.
    • (2007) Drug Metab Dispos , vol.35 , pp. 9-16
    • Webster, R.1    Didier, E.2    Harris, P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.