A two-step association study identifies CAV2 rs2270188 single nucleotide polymorphism interaction with fat intake in type 2 diabetes risk

Journal of Nutrition

Volumn 141, Issue 2, 2011, Pages 177-181

  Fisher, Eva ^a   Schreiber, Stefan ^b   Joost, Hans Georg ^a   Boeing, Heiner ^a   Döring, Frank ^b  

^a GERMAN INSTITUTE OF HUMAN NUTRITION   (Germany)

^b UNIVERSITY OF KIEL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CAVEOLIN 2; FATTY ACID;

ADULT; ALLELE; ARTICLE; CASE CONTROL STUDY; CONTROLLED STUDY; DIABETES MELLITUS; DIETARY INTAKE; DISEASE PREDISPOSITION; FAT INTAKE; FEMALE; GENE INTERACTION; GENETIC ASSOCIATION; GENETIC RISK; GENETIC SCREENING; GENOTYPE; HOMOZYGOTE; HUMAN; MAJOR CLINICAL STUDY; MALE; PROSPECTIVE STUDY; RISK ASSESSMENT; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; ALLELES; CASE-CONTROL STUDIES; CAVEOLIN 2; DIABETES MELLITUS, TYPE 2; DIETARY FATS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; NUTRIGENOMICS; NUTRITIONAL PHYSIOLOGICAL PHENOMENA; POLYMORPHISM, SINGLE NUCLEOTIDE; PPAR GAMMA; PROSPECTIVE STUDIES; QUESTIONNAIRES; RISK FACTORS; STEROL REGULATORY ELEMENT BINDING PROTEIN 1;

EID: 79251500354     PISSN: 00223166     EISSN: 15416100     Source Type: Journal    
DOI: 10.3945/jn.110.124206     Document Type: Article

References (28)

1. Zimmet P, Alberti KG, Shaw J. Global and societal implications of the diabetes epidemic. Nature. 2001;414:782-7.
2. Riserus U. Fatty acids and insulin sensitivity. Curr Opin Clin Nutr Metab Care. 2008;11:100-5.
3. Riserus U, Willett WC, Hu FB. Dietary fats and prevention of type 2 diabetes. Prog Lipid Res. 2009;48:44-51.
4. Fisher E, Nitz I, Lindner I, Rubin D, Boeing H, Mohlig M, Hampe J, Schreiber S, Schrezenmeir J, et al. Candidate gene association study of type 2 diabetes in a nested case-control study of the EPIC-Potsdam cohort: role of fat assimilation. Mol Nutr Food Res. 2007;51:185-91.
5. Nitz I, Fisher E, Grallert H, Li Y, Gieger C, Rubin D, Boeing H, Spranger J, Lindner I, et al. Association of prostaglandin E synthase 2 (PTGES2) Arg298His polymorphism with type 2 diabetes in two German study populations. J Clin Endocrinol Metab. 2007;92: 3183-8.
6. Fisher E, Nitz I, Gieger C, Grallert H, Gohlke H, Lindner I, Dahm S, Boeing H, Burwinkel B, et al. Association of acyl-CoA-binding protein (ACBP) single nucleotide polymorphisms and type 2 diabetes in two German study populations. Mol Nutr Food Res. 2007;51:178-84.
7. Fisher E, Grallert H, Klapper M, Pfafflin A, Schrezenmeir J, Illig T, Boeing H, Doring F. Evidence for the Thr79Met polymorphism of the ileal fatty acid binding protein (FABP6) to be associated with type 2 diabetes in obese individuals. Mol Genet Metab. 2009;98:400-5.
8. Manolio TA, Bailey-Wilson JE, Collins FS. Genes, environment and the value of prospective cohort studies. Nat Rev Genet. 2006;7:812-20.
9. Rundle AG, Vineis P, Ahsan H. Design options for molecular epidemiology research within cohort studies. Cancer Epidemiol Biomarkers Prev. 2005;14:1899-907.
10. Bureau A, Diallo MS, Ordovas JM, Cupples LA. Estimating interaction between genetic and environmental risk factors: efficiency of sampling designs within a cohort. Epidemiology. 2008;19:83-93. (Pubitemid 350295143)
11. Boeing H, Korfmann A, Bergmann MM. Recruitment procedures of EPIC-Germany. European Investigation into Cancer and Nutrition. Ann Nutr Metab. 1999;43:205-15.
12. Bergmann MM, Bussas U, Boeing H. Follow-up procedures in EPIC-Germany- data quality aspects. European Prospective Investigation into Cancer and Nutrition. Ann Nutr Metab. 1999;43:225-34.
13. International HapMap Consortium. A haplotype map of the human genome. Nature. 2005;437:1299-320.
14. Barrett JC, Fry B, Maller J, Daly MJ. Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics. 2005;21:263-5. (Pubitemid 40202029)
15. Bohlscheid-Thomas S, Hoting I, Boeing H, Wahrendorf J. Reproducibility and relative validity of energy and macronutrient intake of a food frequency questionnaire developed for the German part of the EPIC project. European Prospective Investigation into Cancer and Nutrition. Int J Epidemiol. 1997;26 Suppl 1:S71-81.
16. Kroke A, Klipstein-Grobusch K, Voss S, Moseneder J, Thielecke F, Noack R, Boeing H. Validation of a self-administered food-frequency questionnaire administered in the European Prospective Investigation into Cancer and Nutrition (EPIC) Study: comparison of energy, protein, and macronutrient intakes estimated with the doubly labeled water, urinary nitrogen, and repeated 24-h dietary recall methods. Am J Clin Nutr. 1999;70:439-47.
17. Gauderman WJ, Morrison J. QUANTO 1.1: a computer program for power and sample size calculations for genetic-epidemiology studies; 2006 [cited 2007 8 May]. Available from: http://hyda.usc.edu/gxe.
18. Barlow WE, Ichikawa L, Rosner D, Izumi S. Analysis of case-cohort designs. J Clin Epidemiol. 1999;52:1165-72.
19. Chanock SJ, Manolio T, BoehnkeM, Boerwinkle E, Hunter DJ, Thomas G, Hirschhorn JN, Abecasis G, Altshuler D, et al. Replicating genotype-phenotype associations. Nature. 2007;447:655-60.
20. Scherer PE, Okamoto T, Chun M, Nishimoto I, Lodish HF, Lisanti MP. Identification, sequence, and expression of caveolin-2 defines a caveolin gene family. Proc Natl Acad Sci USA. 1996;93:131-5.
21. Scherer PE, Lewis RY, Volonte D, Engelman JA, Galbiati F, Couet J, Kohtz DS, van Donselaar E, Peters P, et al. Cell-type and tissue-specific expression of caveolin-2. Caveolins 1 and 2 co-localize and form a stable hetero-oligomeric complex in vivo. J Biol Chem. 1997;272:29337-46.
22. Parolini I, Sargiacomo M, Galbiati F, Rizzo G, Grignani F, Engelman JA, Okamoto T, Ikezu T, Scherer PE, et al. Expression of caveolin-1 is required for the transport of caveolin-2 to the plasma membrane. Retention of caveolin-2 at the level of the golgi complex. J Biol Chem. 1999;274:25718-25.
23. Yamamoto M, Toya Y, Schwencke C, Lisanti MP, Myers MG Jr, Ishikawa Y. Caveolin is an activator of insulin receptor signaling. J Biol Chem. 1998;273:26962-8. (Pubitemid 28471718)
24. Razani B, Combs TP, Wang XB, Frank PG, Park DS, Russell RG, Li M, Tang B, Jelicks LA, et al. Caveolin-1-deficient mice are lean, resistant to diet-induced obesity, and show hypertriglyceridemia with adipocyte abnormalities. J Biol Chem. 2002;277:8635-47.
25. Razani B, Wang XB, Engelman JA, Battista M, Lagaud G, Zhang XL, Kneitz B, Hou H Jr, Christ GJ, et al. Caveolin-2-deficient mice show evidence of severe pulmonary dysfunction without disruption of caveolae. Mol Cell Biol. 2002;22:2329-44.
26. Cohen AW, Hnasko R, Schubert W, Lisanti MP. Role of caveolae and caveolins in health and disease. Physiol Rev. 2004;84:1341-79.
27. Cao H, Alston L, Ruschman J, Hegele RA. Heterozygous CAV1 frameshift mutations (MIM 601047) in patients with atypical partial lipodystrophy and hypertriglyceridemia. Lipids Health Dis. 2008;7:3.
28. Engelman JA, Zhang XL, Lisanti MP. Sequence and detailed organization of the human caveolin-1 and -2 genes located near the D7S522 locus (7q31.1). Methylation of a CpG island in the 5′ promoter region of the caveolin-1 gene in human breast cancer cell lines. FEBS Lett. 1999;448:221-30.