Icariin promotes osteogenic differentiation of rat bone marrow stromal cells in vitro

Zhongguo Zhongyao Zazhi

Volumn 35, Issue 23, 2010, Pages 3219-3222

  Zhai, Yuankun ^a   Ge, Baofeng ^a   Ma, Huiping ^b   Ming, Leiguo ^a   Li, Zhifeng ^a   Cheng, Guozheng ^a   Zhou, Jian ^a   Chen, Kerning ^a  

^a LANZHOU GENERAL HOSPITAL   (China)

^b Lanzhou Jingcheng Hospital   (China)

Author keywords

BMSCs; Icariin; Osteogenic differentiation

Indexed keywords

ALKALINE PHOSPHATASE; BASIC FIBROBLAST GROWTH FACTOR RECEPTOR; ICARIIN; MESSENGER RNA; SOMATOMEDIN C; TRANSCRIPTION FACTOR OSTERIX; TRANSCRIPTION FACTOR RUNX2;

ANIMAL CELL; ARTICLE; BONE MARROW CELL; CELL ADHESION; CELL DIFFERENTIATION; COLONY FORMING UNIT F; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVITY; GENE EXPRESSION; IN VITRO STUDY; NONHUMAN; OSTEOBLAST; RAT; REAL TIME POLYMERASE CHAIN REACTION; RNA ISOLATION; STROMA CELL;

ALKALINE PHOSPHATASE; ANIMALS; BONE MARROW CELLS; CALCIFICATION, PHYSIOLOGIC; CELL DIFFERENTIATION; CELLS, CULTURED; DRUGS, CHINESE HERBAL; FLAVONOIDS; INSULIN-LIKE GROWTH FACTOR I; MALE; OSTEOGENESIS; RATS; RATS, WISTAR; STROMAL CELLS;

EID: 79251492979     PISSN: 10015302     EISSN: None     Source Type: Journal    
DOI: 10.4268/cjcmm20102330     Document Type: Article

References (8)

1. Chen K M, Ge B F, Ma H P, et al. Icariin, a flavonoid from the herb Epimedium enhances the osteogenic differentiation of rat primary bone marrow stromal cells [J]. Pharmazie, 2005, 60(12): 939.
2. Chen K M, Ge B F, Liu X Y, et al. Icariin inhibits the osteoclast formation induced by RANKL and macrophage-colony stimulating factor in mouse bone marrow culture [J]. Pharmazie, 2006, 62 (5): 388.
3. 'KOMAKI H, TANAKA T, CHAZONO M. Repair of segmental bone defects in rabbit tibiae using a complex of beta-tricalcium phosphate, type I collagen, and fibroblast growth factor-2 [J]. Biomaterials, 2006, 27(29): 5118.