Metabolic pathways of tetraidothyronine and triidothyronine production by thyroid gland: A review of articles

Pakistan Journal of Biological Sciences

Volumn 14, Issue 1, 2011, Pages 1-12

  Mansourian, A R ^a  

^a GOLESTAN UNIVERSITY   (Iran)

Author keywords

Hydrogen peroxide; Tetraidothyronine; Thyroid gland; Thyroperoxidase; Triidothyronine

Indexed keywords

AUTOANTIGEN; HYDROGEN PEROXIDE; IODIDE PEROXIDASE; IODINE; IRON BINDING PROTEIN; LIOTHYRONINE; THYROTROPIN; THYROXINE; TPO PROTEIN, HUMAN;

ANIMAL; ARTICLE; CHEMISTRY; HUMAN; LYSOSOME; METABOLISM; PINOCYTOSIS; THYROID GLAND;

ANIMALS; AUTOANTIGENS; HUMANS; HYDROGEN PEROXIDE; IODIDE PEROXIDASE; IODINE; IRON-BINDING PROTEINS; LYSOSOMES; METABOLIC NETWORKS AND PATHWAYS; PINOCYTOSIS; THYROID GLAND; THYROTROPIN; THYROXINE; TRIIODOTHYRONINE;

EID: 79251485983     PISSN: 10288880     EISSN: 18125735     Source Type: Journal    
DOI: 10.3923/pjbs.2011.1.12     Document Type: Article

References (127)

1. Alquier, C, J. Ruf, A.M. Athouel-Haon and P. Carayon, 1989. Immunocytochemical study of localization and traffic of thyroid peroxidase/microsomal antigen. Autoimmunity, 3: 113-123.
2. Alvmo, C.G., A.M.M. Catanzano and V. Tassi, 1995. Evidence that thyroglobulin has an associated protein kinase activity correlated with the presence of an adenosine triphosphate binding site. Endocrinol., 136: 3179-3185.
3. Andersson, H.C., L.D. Kohn, I. Bernardini, H.J. Blom, F. Tietze and W.A. Gahl, 1990. Characterization of lysosomal monoiodotyrosine transport in rat thyroid cells. Evidence for transport by system h. J. Biol. Chem.,265: 10950-10954.
4. Auso, E., R. Lavado-Autric, E. Cuevas, F.E. Del-Rey, G.M. De Escobar and P. Berbel, 2004. A moderate and transient deficiency of maternal thyroid function at the beginning of fetal neocoticogenesis alters neuronal migration. Endocrinology, 145: 4037-4047.
5. Berndorfer, U., H. Wilms and V. Herzog, 1996. Multimerization of thyroglobulin (TG) during extracellular storage: Isolation of highly cross-linked TG from human thyroids. J. Clin. Endocrinol. Metab., 81: 1918-1926.
6. Beinier-Valentin, F., Z. Kostrouch, R. Rabilloud, Y. Munari-Silem and B. Rousset, 1990. Coated vesicles from thyroid cells carry iodinated thyroglobulin molecules. J. Biol. Chem., 265: 17373-17380.
7. Bjorkman, U. and R. Ekholm, 1992. Hydrogen peroxide generation and its regulation in FRTL-5 and porcine thyroid cells. Endocrinology, 130: 393-399.
8. Boeynaems, J.M., J. van Sande and J.E. Dumont, 1995. Which lipids are involved in thyroid autoregulation: Iodolactones or iodoaldehydes. Eur. J. Endocrinol., 132: 733-734.
9. Cahmann, H.J., J. Pommier and J. Nunez, 1977. Spatial requirement for coupling of iodotyrosine residues to form thyroid hormone. Proc. Natl. Acad. Sci. USA., 74: 5333-5335.
10. Caldwell, K.L., R. Jones and J.G. Hollowell, 2005. Urinary iodine concentration: United States National health and nutrition examination survey 2001 -2002. Thyroid, 15: 692-699.
11. Cao, X.Y., X.M. Jiang, A. Kareem, Z.H. Dou and M.A. Rakeman et al, 1994. Iodination of irrigation water as a method of supplying iodine to a severely iodine-deficient population in Xinjiang, China. Lancet, 344: 107-110.
12. Carvalho, D.P., C. Dupuy, Y. Gorin, O. Legue, J. Pommier, B. Haye and A. Virion, 1996. The Ca2+- and reduced nicotinamide adenine dinucleotide phosphate-dependent hydrogen peroxide generating system is induced by thyrotropin in porcine thyroid cells. Endocrinol, 137: 1007-1012.
13. Cauvi, D., M.C. Mend, N. Venot and O. Chabaud, 2001. Sulfate transport in porcine thyroid cells. Effects of thyroglobulin and iodide. Am. J. Physiol. Endocrinol. Metab., 281: 440-448.
14. Chan, S. and M.D. Kilty, 2000. Thyroid hormone and central nervous system development. J. Endocrinol., 165: 1-8.
15. Cobra, C, Muhilal, K. Rusmil, D. Rustama and Djatnikaet al, 1997. Infant survival is improved by oral iodine supplementation. J. Nutr., 127: 574-578.
16. Consiglio, E., A.M. Acquaviva, S. Formisano, D. Liguoro and A. Gallo et at, 1987. Characterization of phosphate residues on thyroglobulin. J. Biol. Chem., 262: 10304-10314.
17. Consiglio, E., G. Salvatore, J.E. Rail and L.D. Kohn, 1979. Thyroglobulin interactions with thyroid membranes. The existence of specific receptors and their potential role. J. Biol. Chem., 254: 5065-5076.
18. Corvilain, B., E. Laurent, M. Lecomte, J. van Sande and J.E. Dumont, 1994. Role of the cyclic adenosine 3',5'-monophosphate and the phosphatidylinositol-Ca2+ cascades in mediating the effects of thyrotropin and iodide on hormone synthesis and secretion in human thyroid slices. J. Clin. Endocrinol. Metab., 79: 152-159.
19. Corvilain, B., L. Collyn, J. van Sande and J.E. Dumont, 2000. Stimulation by iodide of H202 generation in thyroid slices from several species. Am. J. Physiol. Endocrinol. Metab., 278: 692-699.
20. Czarnocka, B., J. Ruf, M. Ferrand, P. Carayon and S. Lissitzky, 1985. Purification of the human thyroid peroxidase and its identification as the microsomal antigen involved in autoimmune thyroid diseases. FEBS Lett, 190: 147-152.
21. DeDeken, X., D. Wang, M.C. Many, S. Costagliola and F. Libert et al., 2000. Cloning of two human thyroid cDNAs encoding new members of the NADPH oxidase family. J. Biol. Chem., 275: 23227-23233.
22. De Escobar, G.M., M.J. Obregon and F.E. Del-Rey, 2000. Is neuropsychological development related to maternal hypothyroidism or to maternal hypothyroxinemia. J. Clin. Endocrinol. Metab., 85: 3975-3987.
23. De Escobar, G.M., M.J. Obregon and F.E. Del-Rey, 2004. Role of thyroid hormone during early brain development. Eur. J. Endocrinol., 151: 25-37.
24. De Vijlder, J.J., G.J. Veenboer and J.E. Van-Dijk, 1992. Thyroid albumin originates from blood. Endocrinology, 131: 578-584.
25. Delange, F., 2000. Endemic Cretinism. In: The Thyroid. A Fundamental and Clinical Text, Braverman, L.E. and R.D. Utiger (Eds.). Lippincott, Philadelphia, PA., pp: 743-754.
26. Delange, F., 2001. Iodine deficiency as a cause of brain damage. Postgrad. Med. J., 77: 217-220.
27. Delong, G.R., P.W. Leslie, S.H. Wang, X.M. Jiang and M.L. Zhang, et-al, 1997. Effect on infant mortality of iodination of irrigation water in a severely iodine-deficient area of China. Lancet, 350: 771-773.
28. Deme, D., J. Pommier and J. Nunez, 1978. Specificity of thyroid hormone synthesis. The role of thyroid peroxidase. Biochim. Biophys. Acta, 540: 73-82.
29. Dobbing, J. and J. Sands, 1973. Quantitative growth and development of human brain. Arch. Dis. Child., 48: 757-767.
30. Dobbing, J., 1974. The later growth of the brain and its vulnerability. Pediatrics, 53: 2-6.
31. Druetta, L., K. Croizet, H. Bornet and B. Rousset, 1998. Analyses of the molecular forms of serum thyroglobulin from patients with Graves' disease, subacute thyroiditis or differentiated thyroid cancer by velocity sedimentation on sucrose gradient and Western blot. Eur. J. Endocrinol, 139: 498-507.
32. Druetta, L., H. Bornet, G. Sassolas and B. Rousset, 1999. Identification of thyroid hormone residues on serum thyroglobulin: A clue to the source of circulating thyroglobulin in thyroid diseases. Eur. J. Endocrinol, 140: 457-467.
33. Dunn, A.D. and J.T. Dunn, 1982a. Thyroglobulin degradation by thiol proteases: Action of thiol endopeptidases in vitro. Endocrinology, 111: 290-298.
34. Dunn, A.D. and J.T. Dunn, 1982b. Thyroglobulin degradation by thiol proteases: Action of purified CathepsinD. Endocrinol, 11: 280-289.
35. Dunn, J.T., P.S. Kim and A.D. Dunn, 1982. Favoredsites for thyroid hormone formation on the peptide chains of human thyroglobulin. J. Biol. Chem., 257: 88-94.
36. Dunn, J.T., P.S. Kim, A.D. Dunn, D.G. Heppner and R.C. Moore, 1983. The role of iodination in the formation of hormone-rich peptides from thyroglobulin. J. Biol Chem., 258: 9093-9099.
37. Dunn, A.D. and J.T. Dunn, 1988. Cysteine proteinasee from human thyroid and their actions on thyroglobulin. Endocrinology, 123: 1089-1097.
38. Dunn, A.D., H.E. Crutchfield and J.T. Dunn, 1991. Thyroglobulin processing by thyroidal proteases. J. Biol. Chem., 266: 20198-20204.
39. Dunn, A.D., H.E. Muers and J.T. Dunn, 1996. The combined action of two thyroid proteases releases T4 from the dominant hormone-forming site of thyroglobulin. Endocrinology, 137: 3279-3285.
40. Dunn, J.T. and A.D. Dunn, 2008. Thyroglobulin: Chemistry, Biosynthesis and Proteolysis. In: The Thyroid, Braverman, L.E. and R. Utiger (Eds.). Lippincott Williams and Wilkins, Philadelphia, pp: 91-104.
41. Dupuy, C, A. Virion, R. Ohayon, J. Kaniewski, D. Deme and J. Pommier, 1991. Mechanism of hydrogen peroxide formation catalyzed by NADPH oxidase in thyroid plasma membrane. J. Biol. Chem., 266: 3739-3743.
42. Ekholm, R., 1981. Iodination of thyroglobulin. An intracellular or extracellular process. Mol. Cell. Endocrinol, 24: 141-163.
43. Engstrom, G. and L.E. Ericson, 1981. Effect of graded doses of thyrotropin on exocytosis and early phase of endocytosis in the rat thyroid. Endocrinology, 108: 399-405.
44. Ercson, L.E., 1981. Exocytosis and endocytosis in the thyroid cell. Mol. Cell Endocrinol., 22: 1-24.
45. Ericson, L.E. and G. Engstrom, 1978. Quantitative electron microscopic studies on exocytosis and endocytosis in the thyroid follicle cell. Endocrinology, 103: 883-892.
46. Fassler, C.A., J.T. Dunn, P.C. Anderson, J.W. Fox and A.D. Dunn et al., 1988. Thyrotropin alters the utilization of thyroglobulin's hormonogenic sites. J. Biol. Chem., 263: 17366-17371.
47. Fayadat, L., P. Niccoli-Sire, J. Lanet and J.L. Franc, 1998. Human thyroperoxidase is largely retained and rapidly degraded in the endoplasmic reticulum. Its N-glycans are required for folding and intracellular trafficking. Endocrinology, 139: 4277-4285.
48. Fonlupt, P., C. Audebet, V. Gire, F. Bernier-Valentin and B. Rousset, 1997. Calcium is transported into the lumen of pig thyroid follicles by fluid phase basolateral to apical transcytosis. J. Cell Physiol., 171: 42-51.
49. Gavaret, J.M., J. Nunez and H.J. Cahnmann, 1980. Formation of dehydroalanine residues during thyroid hormone synthesis in thyroglobulin. J. Biol. Chem., 255: 5281-5285.
50. Gavaret, J.M., H.J. Cahnmann and J. Nunez, 1981. Thyroid hormone synthesis in thyroglobulin: The mechanism of the coupling reaction. J. Biol. Chem., 256: 9167-9172.
51. Gerber, H., H. Studer and C. von Grunigen, 1985. Paradoxical effects of thyrotropin on diffusion of thyroglobulin in the colloid of rat follicles after long term thyroxine treatment. Endocrinology, 116: 303-310.
52. Gire, V., Z. Kostrouch, F. Bernier-Valentin, R. Rabilloud, Y. Munari-Silem and B. Rousset, 1996. Endocytosis of albumin and thyroglobulin at the basolateral membrane of thyrocytes organized in follicles. Endocrinology, 137: 522-532.
53. Glinoer, D. and F. Delange, 2000. The potential repercussions of maternal, fetal and neonatal hypothyroxinemia on the progeny. Thyroid, 10: 871-887.
54. Haeberli, A., F.K. Millar and S.H. Wormian, 1978. Accumulation and localization of radiocalcium in the rat thyroid gland. Endocrinology, 102: 1511-1519.
55. Hamada, N, L. Portmann and L.J. De-Groot, 1987. Characterization and isolation of thyroid microsomal antigen. J. Clin. Invest, 79: 819-825.
56. Herzog, V., U. Berndorfer and Y. Saber, 1992. Isolation of insoluble secretory product from bovine thyroid: Extracellular storage of thyroglobulin in covalently cross-linked form. J. Cell Biol, 118: 1071-1083.
57. Johanson, V., T. Ofverholm and L.E. Ericson, 1988. Forskolin-induced elevation of cyclic AMP does not cause exocytosis and endocytosis in rat thyroid follicle cells in vivo. Mol. Cell Endocrinol., 59: 27-34.
58. Johnson, T.B. andL.B. Tewkesbury, 1942. The oxydation of 3,5-diiodotyrosine to thyroxine. Proc. Natl. Acad. Sci. USA.,28: 73-77.
59. Kim, P.S., J.T. Dunn and D.L. Kaiser, 1984. Similar hormone-rich peptides from thyroglobulins of five vertebrate classes. Endocrinology, 114: 369-374.
60. Kim, P.S. and P. Arvan, 1998. Endocrinopathies in the family of Endoplasmic Reticulum (ER) storage diseases: Disorders of protein trafficking and the role of ER molecular chaperones. Endocr. Rev., 19: 173-202.
61. Kimura, S., T. Kotam, O.W. McBnde, K. Umeki, K. Hirai, T. Nakayama and S. Ohtaki, 1987. Human thyroid peroxidase: Complete cDNA and protein sequence, chromosome mapping and identification of two alternately spliced mRNAs. Proc. Natl. Acad. Sci. USA., 84: 5555-5559.
62. Kimura, T., F. Okajima, K. Sho, I. Kobayashi and Y. Kondo, 1995. Thyrotropin-induced hydrogen peroxide production in FRTL-5 thyroid cells is mediated not by adenosine 3',5'monophosphate, but by Ca2+ signaling followed by phospholipase-A2 activation and potentiated by an adenosine derivative. Endocrinology, 136: 116-123.
63. Koibuchi, N. and W.W. Chin, 2000. Thyroid hormone action and brain development. Trends Endocrinol. Metab., 4: 123-128.
64. Kotani, T., K. Umeki, S. Matsunaga, E. Kato and S. Ohtaki, 1986. Detection of autoantibodies to thyroid peroxidase in autoimmune thyroid diseases by micro-ELISA and immunoblotting. J. Clin. Endocrinol. Metab., 62: 928-933.
65. Ladenson, P.W., L.E. Braverman, E.L. Mazzaferri, F. Brucker-Davis and D.S. Cooper et ah, 1997. Comparison of administration of recombinant human thyrotropin with withdrawal of thyroid hormone for radioactive iodine scanning in patients with thyroid carcinoma. N. Engl. J. Med., 337: 888-896.
66. Lamas, L., A. Taurog, G. Salvatore and H. Edelhoch, 1974. The importance of thyroglobulin structure i thyroid peroxidase-catalyzed conversion of diiodotyrosine to thyroxine. J. Biol. Chem., 249: 2732-2737.
67. Lamas, L.P.C., Anderson, J.W. Fox and J.T. Dunn, 1989. Consensus sequences for early iodination and hormonogenesis in human thyroglobulin. J. Biol. Chem., 264: 13541-13545.
68. Lenarcie, B., G. Krishnan, R. Borukhovich, B. Ruck, V. Turk and E. Moczydlowski, 2000. Saxiphilin, a saxitoxin-binding protein with two thyroglobulin typel domains, is an inhibitor of papain-like cysteine. J. Biol. Chem., 275: 15572-15577.
69. Libert, F., J. Ruel, M. Ludage, S. Swillens, N. Alexander, G. Vassartand, C. Dinsart, 1987. Thyroperoxidase, an auto-antigen with a mosaic structure made of nuclear and mitochondrial gene modules. EMBO J., 6: 4193-4196.
70. Linke, M., V. Herzog and K. Brix, 2002. Trafficking of lysosomal cathepsin B-green fluorescent protein to the surface of thyroid epithelial cells involves the endosomal/lysosomal compartment. J. Cell Sci., 115: 4877-4889.
71. Lisi, S., A. Pinchera, R.T. McCluskey, T.E. Willow and S. Refetoff et-al, 2003. Preferential megalin-mediated transcytosis of low hormonogenic thyroglobulin: A control mechanism for thyroid hormone release. Proc. Natl. Acad. Sci. USA., 100: 14858-14863.
72. Maberly, G.F., C.J. Eastman and J.M. Corcoran, 1981. Effect of iodination of a village water-supply on goitre size and thyroid function. Lancet, 318: 1270-1272.
73. Mansourian, A.R. and A.R. Ahmadi, 2010. Correlation between inverse age and serum thyroxine level among children and adolescents. J. Clin. Diagnostic Res., 4: 3196-3200.
74. Mansourian, A.R., 2010a. A review on post-Puberty Hypothyroidism: A galance at Myxedema. Pak. J. Biol. Sci., 13: 866-876.
75. Mansourian, A.R., 2010b. The state of lipid profiles in subclinical hypothyroidism: A review of literature. Pak. J. Biol. Sci., 13: 556-562.
76. Mansourian, A.R., 2010c. Thyroid function tests during first: Trimester of pregnancy: A review of literature. Pak. J. Biol. Sci., 13: 664-673.
77. Mansourian, A.R., 2010d. The immune system which adversely alter thyroid functions: A review on the concept of autoimmunity. Pak. J. Biol. Sci., 13: 765-774.
78. Mansourian, A.R., 2010e. A review on hyperthyroidism: Thyrotoxicosis under surveillance. Pak. J. Biol. Sci., 13: 1066-1076.
79. Mansourian, A.R., A.R. Ahmadi, A. Saifi and S. Bakhshandehnosrat, 2010a. The children reference range of thyroid hormones in Northern Iran. Pak. J. Biol. Sci., 13: 862-865.
80. Mansourian, A.R., A.R. Ahmadi, H.R Mansourian, A. Sifi, A. Marjani and E. Ghaemi, 2010b. Maternal thyroid stimulating hormone level during the first trimester of pregnancy at South East of Caspian sea in Iran. J. Clin. Diagnostic Res., 4: 2472-2477.
81. Mansourian, A.R., E.O. Ghaemi, A. Ahmadi, A. Marjani, A. Saifi and S. Bakhshandehnosrat, 2008. Serum lipid level alteration in sub clinical hypothyroid patients in Gorgan (South East Caspian Sea). J. Chinese Clin. Med., 3: 206-210.
82. Mansourian, A.R., E.O. Ghaemi, A.R. Ahmadi, A. Saifi, A.V. Moradi and S. Bakhshandehnosrat 2007. A survy of urinary iodine concentration in South East of Northern Iran. Pak. J. Biol. Sci., 10: 2166-2177.
83. Marino, M. and R.T. McCluskey, 2000. Role of thyroglobulin endocytic pathways in the control of thyroid hormone release. Am. J. Physiol. Cell Physiol, 279: 1295-1306.
84. Marino, M., G. Zheng, L. Chivato, A. Pinchera, D. Brown, D. Andrews and R.T. McCluskey, 2000. Role of megalin (gp330) in transcytosis of thyroglobulin by thyroid cells. A novel function in the control of thyroid hormone release. J. Biol. Chem., 275: 7125-7137.
85. Marriq, C, P.J. Lejeune, N. Venot and L. Vinet, 1991. Hormone formation in the isolated fragment 1-171 of human thyroglobulin involves the couple tyrosine 5 and tyrosine 130. Mol. Cell Endocrinol, 81: 155-164.
86. Mazzaferri, E.L., R.J. Robbins, C.A. Spencer, L.E. Braverman and F. Pacini et al., 2003. A concensus report of the role of serum thyroglobulin as a monitoring method for low-risk patients with papillary thyroid carcinomas. J. Clin. Endocrinol. Metab., 88: 1433-1441.
87. McDougall, I.R. and R.J. Weigel, 2001. Recombinant human thyrotropin in the management of thyroid cancer. Curr. Opin. Oncol., 13: 39-43.
88. Medeiros-Neto, G. and J.B. Stanbury, 1994. The Iodotyrosine Deiodinase Defect. In: Inherited Disorders of the Thyroid System, Medeiros-Neto, G. and J.B. Stanbury (Eds.). CRC Press, Boca Raton.
89. Medeiros-Neto, G., P.S. Kim, S.E. Yoo, J. Vono and H.M. Targovnik et al., 1996. Congenital hypothyroid goiter with deficient thyroglobulin. Identification of an endoplasmic reticulum storage disease with induction of molecular chaperones. J. Clin. Invest, 98: 2838-2844.
90. Mendive, F.M., CM. Rivolta, CM. Moya, G. Vassart and H.M. Targovnik, 2001. Genomic organization of the human thyroglobulin gene: The complete intron-exon structure. Eur. J. Endocrinol., 145: 485-496.
91. Mercken, L., M.J. Simons, S. Swillens, M. Massaer and G. Vassart, 1985. Primary structure of bovine thyroglobulin deduced from the sequence of its 8,431-base complementary DNA. Nat., 316: 647-651.
92. Montuori, N., F. Pacifico, S. Mellone, D. Liguoro and B. Di-Jeso et al., 2000. The rat asialoglycoprotein receptor binds the amino-terminal domain of thyroglobulin. Biochem. Biophys. Res. Commun., 268: 42-46.
93. Muresan, Z. and P. Arvan, 1997. Thyroglobulin transport along the secretory pathway. J. Biol. Chem., 272: 26095-26102.
94. Muresan, Z. and P. Arvan, 1998. Enhanced binding to the molecular chaperone BiP slows thyroglobulin export from the endoplasmic reticulum. Mol. Endocrinol., 12: 458-467.
95. Nakamura, Y., S. Ohtaki, R. Makino, T. Tanaka and Y. Ishimura, 1989. Superoxide anion is the initial product in the hydrogen peroxide formation catalyzed by NADPH oxidase in porcine thyroid plasma membrane. J. Biol. Chem., 264: 4759-4761.
96. Neve, P., C. Willems and J.E. Dumont, 1970. Involvement of the microtubule-microfilament system in thyroid secretion. Exp. Cell Res., 63: 457-460.
97. Niepomniszcze, H., L.J. De Groot and G.A. Hagen, 1972. Abnormal thyroid peroxidase causing iodide organification defect. J. Clin. Endocrinol. Metab., 34: 607-607.
98. Ofverholm, T. and L.E. Ericson, 1984. Intralumenal iodination of thyroglobulin. Endocrinology, 114: 827-835.
99. Ohtaki, S., H. Nakagawa, S. Kimura and I. Yamazaki, 1981. Analyses of catalytic intermediates of hog thyroid peroxidase during its iodinating reaction. J. Biol. Chem., 256: 805-810.
100. Ohtaki, S., S. Monya, H. Suzuki and Y. Honuchi, 1967. Nonhormonal iodine escape from the normal and abnormal thyroid gland. J. Clin. Endocrinol. Metab., 27: 728-740.
101. Ohyama, Y., T. Hosoya, T. Kameya, N. Suzuki and S. Nakamura et al., 1994. Congenital euthyroid goitre with impaired thyroglobulin transport. Clin. Endocrinol, 41: 129-135.
102. Pharoah, P.O.D. and K.J. Connolly, 1987. A controlled trial of iodinated oil for the prevention of endemic cretinism: A long-term follow-up. Int. J. Epidemiol., 16: 68-73.
103. Pierce, L.R., C. Zurzolo, G. Salvatore, and H. Edelhoch, 1985. Coated vesicles from the thyroid gland: Isolation, characterization and a search for a possible role in thyroglobulin transport. J. Endocrinol. Invest., 8: 303-312.
104. Portmann, L., N. Hamada, G. Heinrich and L.J. De-Groot, 1985. Antithyroid peroxidase antibody in patients with autoimmune thyroid disease: Possible identity with antimicrosomal antibody. J. Clin. Endocrinol. Metab., 61: 1001-1003.
105. Robbins, J., J. Wolff and J.E. Rail, 1959. Iodoproteins in normal and abnormal human thyroid tissue and in normal sheep thyroid. Endocrinology, 64: 37-52.
106. Robbins, R. J., R. M. Tuttle, R.N. Sharaf, S.M. Larson and H.K. Robbins et-al, 2001. Preparation by recombinant human thyrotropin or thyroid hormone withdrawal are comparable for the detection of residual differentiated thyroid carcinomas. J. Clin. Endocr. Metab., 86: 619-625.
107. Rosenberg, I.N. and A. Goswami, 1979. Purification and characterization of a flavoprotein from bovine thyroid with iodotyrosine deiodinase activity. J. Biol. Chem., 254: 12318-12385.
108. Rousset, B. and R. Mornex, 1991. The thyroid hormone secretary pathway-Current dogmas and alternative hypotheses. Mol. Cell Endocrinol., 78: 89-93.
109. Ruf, J., B. Czarnocka, C. De Micco, C. Dutoit, M. Ferrand and P. Carayon, 1987. Thyroid peroxidase is the organ-specific 'microsomal' autoantigen involved in thyroid autoimmunity. Acta Endocrinol. Suppl., 281: 49-56.
110. Schlumberger, M., M. Ricard and F. Pacini, 2000. Clinical use of recombinant human TSH in thyroid cancer patients. Eur. J. Endocrinol, 143: 557-563.
111. Schneider, A.B., K. Ikekubo and K. Kuma, 1983. Iodine content of serum thyroglobulin in normal individuals and patients with thyroid tumors. J. Clin. Endocrinol. Metab., 57: 1251-1256.
112. Selmi, S. and B. Rousset, 1988. Identification of two subpopulations of thyroid lysosomes: Relation to the thyroglobulin proteolytic pathway. Biochem. J., 253: 523-532.
113. Seto, P., H. Hirayu, R.P. Magnusson, J. Gestautas, L. Portmann, L.J. De Groot and B. Rapoport, 1987. Isolation of a complementary DNA clone for thyroid microsomal antigen. Homology with the gene for thyroid peroxidase. J. Clin. Invest., 80: 1205-1208.
114. Shahmohammdi, F., A.R. Mansourian and H.R Mansourian, 2008. Serum thyroid hormone level in women with nausea and vomiting in early pregnancy. J. Medical Sci., 8: 507-510.
115. Spencer, C.A., 2000. Serum thyroglobulin measurements: Clinical utility and technical limitations in the management of patients with differentiated thyroid carcinomas. Endocr. Pract, 6: 481-484.
116. Spiro, M.J. and K.M. Gorski, 1986. Studies on the posttranslational migration and processing of thyroglobulin: Use of inhabitors and evaluation of the role of phosphorylation. Endocrinology, 119: 1146-1158.
117. Spiro, M.J., 1977. Presence of a glucuronic acid-containing carbohydrate unit in human thyroglobulin. J. Biol. Chem., 252: 5424-5430.
118. Targovnik, H.M., J. Vono, A.E. Billerbeck, G.E. Cerrone and V. Varela et-al., 1995. A 138-nucleotide deletion in the thyroglobulin ribonucleic acid messenger in a congenital goiter with defective thyroglobulin synthesis. J. Clin. Endocrinol. Metab., 80: 3356-3360.
119. Tietze, F., L.D. Kohn, A.D. Kohn, I. Bernardini and H.C. Andersson et al., 1989. Carrier-mediated transport of monoiodotyrosine out of thyroid cell lysosomes. J. Biol. Chem., 264: 4762-4765.
120. Tonglet, R., P. Bourdoux, T. Minga and A.M. Ermans, 1992. Efficacy of low oral doses of iodized oil in the control of iodine deficiency in Zaire. New Engl. J. Med., 326: 236-241.
121. Toyoda, N, M. Nishikawa, Y. Mori, M. Yoshimura and H. Masaki et al., 1992. Identification of a 27-kilodalton protein with the properties of type I Iodothyronine 5' -deiodinase in human thyroid gland. J. Clin. Endocrinol. Metab., 74: 533-538.
122. Virion, A., F. Courtin, D. Deme, J.L. Michot, J. Kaniewski and J. Pommier, 1985. Spectral characteristics and catalytic properties of thyroid peroxidase-H202 compounds in the iodination and coupling reactions. Arch. Biochem. Biophys., 242: 41-47.
123. Virion, A., J. Pommier, D. Deme and J. Nunez, 1981. Kinetics of thyroglobulin iodination and thyroid hormone synthesis catalyzed by peroxidase: The role ofHA-Eur. J. Biochem., 117: 103-109.
124. Wartofsky, L. and rhTSH-Stimulated Thyroglobulin Study Group, 2002. Management of low-risk well-differentiated thyroid cancer based only on thyroglobulin measurement after recombinant human thyrotropin. Thyroid, 12: 583-590.
125. Wolff, J. and l.L. Chaikoff, 1948. Plasma inorganic iodide as a homeostatic regulator of thyroid function. J. Biol. Chem., 174: 555-564.
126. Wollman, S.H. and R. Ekholm, 1981. Site of iodination in hyperplastic thyroid glands deduced from autoradiographs. Endocrinology, 108: 2082-2085.
127. Yamamoto, K., T. Tsuji, O. Tarutani and T. Osawa, 1984. Structural changes of carbohydrate chains of human thyroglobulin accompanying malignant transformations of thyroid glands. Eur. J. Biochem., 143: 133-144.