Determination of plasma and skin concentrations of orbifloxacin in dogs with clinically normal skin and dogs with pyoderma

Veterinary Therapeutics

Volumn 3, Issue 4, 2002, Pages

  Kay Mugford, Patricia ^a   Weingarten, Allan ^a   Ngoh, Maureen ^a   Zolynas, Robert ^a   White, Amy ^a   Katz, Terry ^a   Simmons, Robert ^a   Varma, Kanwal ^a   Basilio, Paul ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALIA; CANIS FAMILIARIS;

EID: 79251483172     PISSN: 15283593     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (13)

1. Product information: Orbax® Union NJ, Schering-Plough Animal Health, 1997.
2. Wolfson JS, Hooper DC: Fluoroquinolone antimicrobial agents. Clin Microbiol Rev 2:378-424, 1989.
3. Heinen E: Comparative serum pharmacokinetics of the fluoroquinolones enrofloxacin, difloxacin, marbofloxacin, and orbifloxacin in dogs after single oral administration. J Vet Pharmacol Ther 25:1-5, 2002.
4. Freedom of Information Summary: Orbax. NADA 141-081. Rockville, MD, FDA, April 22, 1997.
5. Sisco WM, Ihrke PJ, Franti CE: Regional distribution of the common skin diseases in dogs. JAVMA 195:752-756, 1989.
6. Hill PB, Moriello KA: Canine pyoderma. JAVMA 204(3):334-340, 1994.
7. Scott DW, Miller WH, Griffin CE: Canine pyoderma, in Muller GH, Kirk RW (eds): Small Animal Dermatology, ed 5. Philadelphia, WB Saunders, 1995, pp 290-296, 298-312.
8. Wisselink MA, Bouw S, der Weduwen SA, et al: German shepherd dog pyoderma: A genetic disorder. Vet Q 11:161-164, 1989.
9. Chabanne L, Marchal T, Denerolle P, et al: Lymphocyte subset abnormalities in German shepherd dog pyoderma (GSP). Vet Immunol Immunopathol 49:189-198, 1995.
10. DeManuelle TC, Ihrke PJ, Brandt CM, et al: Determination of skin concentrations of enrofloxacin in dogs with pyoderma. Am J Vet Res 59(12):1599-1604, 1998.
11. NCCLS: Performance Standards for Antimicrobial Disk and Dilution Susceptibility Tests for Bacteria Isolated from Animals: Approved Standards. NCCLS Document M31-A2 22, Wayne, PA, NCCLS, May 2002.
12. Berg JN, Wendell DE, Vogelweid CM, et al: Identification of the major coagulase-positive Staphylococcus spp of dogs as Staphylococcus intermedius. Am J Vet Res 45:1307-1309, 1984.
13. Wright DH, Brown GH, Peterson ML, Rotschafer JC: Application of fluoroquinolone pharmacodynamics. J Antimicrob Chemother 46:669-683, 2000.