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Volumn 6, Issue 11, 2010, Pages

SV2 mediates entry of tetanus neurotoxin into central neurons

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; NEUROTOXIN; SV2A PROTEIN; SV2B PROTEIN; SYNAPTOBREVIN 2; TETANUS TOXIN; UNCLASSIFIED DRUG; MEMBRANE PROTEIN; NERVE PROTEIN; SV2A PROTEIN, MOUSE; SV2B PROTEIN, MOUSE;

EID: 79251482759     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1001207     Document Type: Article
Times cited : (107)

References (65)
  • 2
    • 0010281124 scopus 로고
    • Die Pathogenie des Tetanus
    • Faber K (1890) Die Pathogenie des Tetanus. Berl Klin Wochenschr 27: 710-717.
    • (1890) Berl Klin Wochenschr , vol.27 , pp. 710-717
    • Faber, K.1
  • 3
    • 0013043997 scopus 로고
    • Untersuchungen uber das Tetanusgift
    • Tizzoni G, Cattani G (1890) Untersuchungen uber das Tetanusgift. Zentralbl Bakt 8: 69-73.
    • (1890) Zentralbl Bakt , vol.8 , pp. 69-73
    • Tizzoni, G.1    Cattani, G.2
  • 6
    • 0027219725 scopus 로고
    • Botulinum neurotoxin A selectively cleaves the synaptic protein SNAP-25
    • Blasi J, Chapman ER, Link E, Binz T, Yamasaki S, et al. (1993) Botulinum neurotoxin A selectively cleaves the synaptic protein SNAP-25. Nature 365: 160-163.
    • (1993) Nature , vol.365 , pp. 160-163
    • Blasi, J.1    Chapman, E.R.2    Link, E.3    Binz, T.4    Yamasaki, S.5
  • 7
    • 0027432376 scopus 로고
    • Botulinum neurotoxin C1 blocks neurotransmitter release by means of cleaving HPC-1/ syntaxin
    • Blasi J, Chapman ER, Yamasaki S, Binz T, Niemann H, et al. (1993) Botulinum neurotoxin C1 blocks neurotransmitter release by means of cleaving HPC-1/ syntaxin. Embo J 12: 4821-4828.
    • (1993) Embo J , vol.12 , pp. 4821-4828
    • Blasi, J.1    Chapman, E.R.2    Yamasaki, S.3    Binz, T.4    Niemann, H.5
  • 8
    • 0027997409 scopus 로고
    • Botulinum G neurotoxin cleaves VAMP/synaptobrevin at a single Ala- Ala peptide bond
    • Schiavo G, Malizio C, Trimble WS, Polverino de Laureto P, Milan G, et al. (1994) Botulinum G neurotoxin cleaves VAMP/synaptobrevin at a single Ala- Ala peptide bond. J Biol Chem 269: 20213-20216.
    • (1994) J Biol Chem , vol.269 , pp. 20213-20216
    • Schiavo, G.1    Malizio, C.2    Trimble, W.S.3    De Laureto, P.P.4    Milan, G.5
  • 9
    • 0027438184 scopus 로고
    • Botulinum neurotoxins serotypes A and E cleave SNAP-25 at distinct COOHterminal peptide bonds
    • Schiavo G, Santucci A, Dasgupta BR, Mehta PP, Jontes J, et al. (1993) Botulinum neurotoxins serotypes A and E cleave SNAP-25 at distinct COOHterminal peptide bonds. FEBS Lett 335: 99-103.
    • (1993) FEBS Lett , vol.335 , pp. 99-103
    • Schiavo, G.1    Santucci, A.2    Dasgupta, B.R.3    Mehta, P.P.4    Jontes, J.5
  • 10
    • 0026497466 scopus 로고
    • Tetanus and botulinum-B neurotoxins block neurotransmitter release by proteolytic cleavage of synaptobrevin
    • Schiavo G, Benfenati F, Poulain B, Rossetto O, Polverino de Laureto P, et al. (1992) Tetanus and botulinum-B neurotoxins block neurotransmitter release by proteolytic cleavage of synaptobrevin. Nature 359: 832-835.
    • (1992) Nature , vol.359 , pp. 832-835
    • Schiavo, G.1    Benfenati, F.2    Poulain, B.3    Rossetto, O.4    De Laureto, P.P.5
  • 11
    • 58849092285 scopus 로고    scopus 로고
    • Membrane fusion: Grappling with SNARE and SM proteins
    • Sudhof TC, Rothman JE (2009) Membrane fusion: grappling with SNARE and SM proteins. Science 323: 474-477.
    • (2009) Science , vol.323 , pp. 474-477
    • Sudhof, T.C.1    Rothman, J.E.2
  • 12
    • 0036304982 scopus 로고    scopus 로고
    • Synaptotagmin: A Ca(2+) sensor that triggers exocytosis?
    • Chapman ER (2002) Synaptotagmin: a Ca(2+) sensor that triggers exocytosis? Nat Rev Mol Cell Biol 3: 498-508.
    • (2002) Nat Rev Mol Cell Biol , vol.3 , pp. 498-508
    • Chapman, E.R.1
  • 13
    • 0003546691 scopus 로고
    • Botulism: The organism, its toxins, the disease
    • USA: Thomas
    • Smith LDS, Sugiyama H (1988) Botulism: the organism, its toxins, the disease. SpringfieldIll., USA: Thomas. pp xi, 171.
    • (1988) SpringfieldIll
    • Smith, L.D.S.1    Sugiyama, H.2
  • 14
    • 0035168442 scopus 로고    scopus 로고
    • Lipid rafts act as specialized domains for tetanus toxin binding and internalization into neurons
    • Herreros J, Ng T, Schiavo G (2001) Lipid rafts act as specialized domains for tetanus toxin binding and internalization into neurons. Mol Biol Cell 12: 2947-2960.
    • (2001) Mol Biol Cell , vol.12 , pp. 2947-2960
    • Herreros, J.1    Ng, T.2    Schiavo, G.3
  • 16
    • 29644438627 scopus 로고    scopus 로고
    • Tetanus toxin is transported in a novel neuronal compartment characterized by a specialized pH regulation
    • Bohnert S, Schiavo G (2005) Tetanus toxin is transported in a novel neuronal compartment characterized by a specialized pH regulation. J Biol Chem 280: 42336-42344.
    • (2005) J Biol Chem , vol.280 , pp. 42336-42344
    • Bohnert, S.1    Schiavo, G.2
  • 17
    • 33749620373 scopus 로고    scopus 로고
    • Rab5 and Rab7 Control Endocytic Sorting along the Axonal Retrograde Transport Pathway
    • Deinhardt K, Salinas S, Verastegui C, Watson R, Worth D, et al. (2006) Rab5 and Rab7 Control Endocytic Sorting along the Axonal Retrograde Transport Pathway. Neuron 52: 293-305.
    • (2006) Neuron , vol.52 , pp. 293-305
    • Deinhardt, K.1    Salinas, S.2    Verastegui, C.3    Watson, R.4    Worth, D.5
  • 18
    • 0018716059 scopus 로고
    • Selective retrograde transsynaptic transfer of a protein, tetanus toxin, subsequent to its retrograde axonal transport
    • Schwab ME, Suda K, Thoenen H (1979) Selective retrograde transsynaptic transfer of a protein, tetanus toxin, subsequent to its retrograde axonal transport. J Cell Biol 82: 798-810.
    • (1979) J Cell Biol , vol.82 , pp. 798-810
    • Schwab, M.E.1    Suda, K.2    Thoenen, H.3
  • 19
    • 0014431104 scopus 로고
    • Tetanus toxin and spinal inhibition
    • Curtis DR, De Groat WC (1968) Tetanus toxin and spinal inhibition. Brain Res 10: 208-212.
    • (1968) Brain Res , vol.10 , pp. 208-212
    • Curtis, D.R.1    de Groat, W.C.2
  • 20
    • 46149134882 scopus 로고
    • How do tetanus and botulinum toxins bind to neuronal membranes?
    • Montecucco C (1986) How do tetanus and botulinum toxins bind to neuronal membranes? Trends in Biochemical Sciences 11: 314-317.
    • (1986) Trends in Biochemical Sciences , vol.11 , pp. 314-317
    • Montecucco, C.1
  • 21
    • 0032872478 scopus 로고    scopus 로고
    • Gangliosides are the binding substances in neural cells for tetanus and botulinum toxins in mice
    • Kitamura M, Takamiya K, Aizawa S, Furukawa K, Furukawa K (1999) Gangliosides are the binding substances in neural cells for tetanus and botulinum toxins in mice. Biochim Biophys Acta 1441: 1-3.
    • (1999) Biochim Biophys Acta , vol.1441 , pp. 1-3
    • Kitamura, M.1    Takamiya, K.2    Aizawa, S.3    Furukawa, K.4    Furukawa, K.5
  • 22
    • 20444431618 scopus 로고    scopus 로고
    • Different response of the knockout mice lacking b-series gangliosides against botulinum and tetanus toxins
    • Kitamura M, Igimi S, Furukawa K, Furukawa K (2005) Different response of the knockout mice lacking b-series gangliosides against botulinum and tetanus toxins. Biochim Biophys Acta 1741: 1-3.
    • (2005) Biochim Biophys Acta , vol.1741 , pp. 1-3
    • Kitamura, M.1    Igimi, S.2    Furukawa, K.3    Furukawa, K.4
  • 23
    • 0022539795 scopus 로고
    • Characterization of tetanus toxin binding to rat brain membranes. Evidence for a high-affinity proteinase-sensitive receptor
    • Pierce EJ, Davison MD, Parton RG, Habig WH, Critchley DR (1986) Characterization of tetanus toxin binding to rat brain membranes. Evidence for a high-affinity proteinase-sensitive receptor. Biochem J 236: 845-852.
    • (1986) Biochem J , vol.236 , pp. 845-852
    • Pierce, E.J.1    Davison, M.D.2    Parton, R.G.3    Habig, W.H.4    Critchley, D.R.5
  • 24
    • 0023781370 scopus 로고
    • Tetanus toxin binding to mouse spinal cord cells: An evaluation of the role of gangliosides in toxin internalization
    • Parton RG, Ockleford CD, Critchley DR (1988) Tetanus toxin binding to mouse spinal cord cells: an evaluation of the role of gangliosides in toxin internalization. Brain Res 475: 118-127.
    • (1988) Brain Res , vol.475 , pp. 118-127
    • Parton, R.G.1    Ockleford, C.D.2    Critchley, D.R.3
  • 25
    • 0022452373 scopus 로고
    • Tetanus toxin receptors on nerve cells contain a trypsin-sensitive component
    • Yavin E, Nathan A (1986) Tetanus toxin receptors on nerve cells contain a trypsin-sensitive component. Eur J Biochem 154: 403-407.
    • (1986) Eur J Biochem , vol.154 , pp. 403-407
    • Yavin, E.1    Nathan, A.2
  • 26
    • 15544380203 scopus 로고    scopus 로고
    • Endocytosis and retrograde axonal traffic in motor neurons
    • Deinhardt K, Schiavo G (2005) Endocytosis and retrograde axonal traffic in motor neurons. Biochem Soc Symp. pp 139-150.
    • (2005) Biochem Soc Symp , pp. 139-150
    • Deinhardt, K.1    Schiavo, G.2
  • 27
    • 33646248918 scopus 로고    scopus 로고
    • SV2 is the protein receptor for botulinum neurotoxin A
    • Dong M, Yeh F, Tepp WH, Dean C, Johnson EA, et al. (2006) SV2 is the protein receptor for botulinum neurotoxin A. Science 312: 592-596.
    • (2006) Science , vol.312 , pp. 592-596
    • Dong, M.1    Yeh, F.2    Tepp, W.H.3    Dean, C.4    Johnson, E.A.5
  • 28
    • 38049036925 scopus 로고    scopus 로고
    • Mechanism of botulinum neurotoxin B and G entry into hippocampal neurons
    • Dong M, Tepp WH, Liu H, Johnson EA, Chapman ER (2007) Mechanism of botulinum neurotoxin B and G entry into hippocampal neurons. J Cell Biol 179: 1511-1522.
    • (2007) J Cell Biol , vol.179 , pp. 1511-1522
    • Dong, M.1    Tepp, W.H.2    Liu, H.3    Johnson, E.A.4    Chapman, E.R.5
  • 29
    • 0141641129 scopus 로고    scopus 로고
    • Synaptotagmins I and II mediate entry of botulinum neurotoxin B into cells
    • Dong M, Richards DA, Goodnough MC, Tepp WH, Johnson EA, et al. (2003) Synaptotagmins I and II mediate entry of botulinum neurotoxin B into cells. J Cell Biol 162: 1293-1303.
    • (2003) J Cell Biol , vol.162 , pp. 1293-1303
    • Dong, M.1    Richards, D.A.2    Goodnough, M.C.3    Tepp, W.H.4    Johnson, E.A.5
  • 31
    • 0028341442 scopus 로고
    • Identification of protein receptor for Clostridium botulinum type B neurotoxin in rat brain synaptosomes
    • Nishiki T, Kamata Y, Nemoto Y, Omori A, Ito T, et al. (1994) Identification of protein receptor for Clostridium botulinum type B neurotoxin in rat brain synaptosomes. J Biol Chem 269: 10498-10503.
    • (1994) J Biol Chem , vol.269 , pp. 10498-10503
    • Nishiki, T.1    Kamata, Y.2    Nemoto, Y.3    Omori, A.4    Ito, T.5
  • 32
    • 33645212684 scopus 로고    scopus 로고
    • The synaptic vesicle protein 2C mediates the uptake of botulinum neurotoxin A into phrenic nerves
    • Mahrhold S, Rummel A, Bigalke H, Davletov B, Binz T (2006) The synaptic vesicle protein 2C mediates the uptake of botulinum neurotoxin A into phrenic nerves. FEBS Lett 580: 2011-2014.
    • (2006) FEBS Lett , vol.580 , pp. 2011-2014
    • Mahrhold, S.1    Rummel, A.2    Bigalke, H.3    Davletov, B.4    Binz, T.5
  • 33
    • 3142735021 scopus 로고    scopus 로고
    • Synaptotagmins I and II act as nerve cell receptors for botulinum neurotoxin G
    • Rummel A, Karnath T, Henke T, Bigalke H, Binz T (2004) Synaptotagmins I and II act as nerve cell receptors for botulinum neurotoxin G. J Biol Chem 279: 30865-30870.
    • (2004) J Biol Chem , vol.279 , pp. 30865-30870
    • Rummel, A.1    Karnath, T.2    Henke, T.3    Bigalke, H.4    Binz, T.5
  • 34
    • 0029847230 scopus 로고    scopus 로고
    • Synaptic vesicle endocytosis mediates the entry of tetanus neurotoxin into hippocampal neurons
    • Matteoli M, Verderio C, Rossetto O, Iezzi N, Coco S, et al. (1996) Synaptic vesicle endocytosis mediates the entry of tetanus neurotoxin into hippocampal neurons. Proc Natl Acad Sci U S A 93: 13310-13315.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 13310-13315
    • Matteoli, M.1    Verderio, C.2    Rossetto, O.3    Iezzi, N.4    Coco, S.5
  • 35
    • 0035976767 scopus 로고    scopus 로고
    • High sensitivity of mouse neuronal cells to tetanus toxin requires a GPI-anchored protein
    • Munro P, Kojima H, Dupont JL, Bossu JL, Poulain B, et al. (2001) High sensitivity of mouse neuronal cells to tetanus toxin requires a GPI-anchored protein. Biochem Biophys Res Commun 289: 623-629.
    • (2001) Biochem Biophys Res Commun , vol.289 , pp. 623-629
    • Munro, P.1    Kojima, H.2    Dupont, J.L.3    Bossu, J.L.4    Poulain, B.5
  • 36
    • 0023196480 scopus 로고
    • A study of the mechanism of internalisation of tetanus toxin by primary mouse spinal cord cultures
    • Parton RG, Ockleford CD, Critchley DR (1987) A study of the mechanism of internalisation of tetanus toxin by primary mouse spinal cord cultures. J Neurochem 49: 1057-1068.
    • (1987) J Neurochem , vol.49 , pp. 1057-1068
    • Parton, R.G.1    Ockleford, C.D.2    Critchley, D.R.3
  • 37
    • 0034006039 scopus 로고    scopus 로고
    • Tetanus toxin fragment C binds to a protein present in neuronal cell lines and motoneurons
    • Herreros J, Lalli G, Montecucco C, Schiavo G (2000) Tetanus toxin fragment C binds to a protein present in neuronal cell lines and motoneurons. J Neurochem 74: 1941-1950.
    • (2000) J Neurochem , vol.74 , pp. 1941-1950
    • Herreros, J.1    Lalli, G.2    Montecucco, C.3    Schiavo, G.4
  • 39
    • 0040416564 scopus 로고
    • The reaction of ''tetanus sensitive'' and ''tetanus resistant'' animals to the injection of tetanal toxin into the spinal cord
    • Schumaker HB, Lamont A, Firor WM (1939) The reaction of ''tetanus sensitive'' and ''tetanus resistant'' animals to the injection of tetanal toxin into the spinal cord. J Immunol 37: 425-433.
    • (1939) J Immunol , vol.37 , pp. 425-433
    • Schumaker, H.B.1    Lamont, A.2    Firor, W.M.3
  • 40
    • 0346496235 scopus 로고    scopus 로고
    • A multi-domain protein system based on the HC fragment of tetanus toxin for targeting DNA to neuronal cells
    • Box M, Parks DA, Knight A, Hale C, Fishman PS, et al. (2003) A multi-domain protein system based on the HC fragment of tetanus toxin for targeting DNA to neuronal cells. J Drug Target 11: 333-343.
    • (2003) J Drug Target , vol.11 , pp. 333-343
    • Box, M.1    Parks, D.A.2    Knight, A.3    Hale, C.4    Fishman, P.S.5
  • 42
    • 0032842847 scopus 로고    scopus 로고
    • Functional characterisation of tetanus and botulinum neurotoxins binding domains
    • Lalli G, Herreros J, Osborne SL, Montecucco C, Rossetto O, et al. (1999) Functional characterisation of tetanus and botulinum neurotoxins binding domains. J Cell Sci 112(Pt 16): 2715-2724.
    • (1999) J Cell Sci , vol.112 , Issue.PART 16 , pp. 2715-2724
    • Lalli, G.1    Herreros, J.2    Osborne, S.L.3    Montecucco, C.4    Rossetto, O.5
  • 43
    • 33947392128 scopus 로고    scopus 로고
    • Association of botulinum neurotoxin serotypes a and B with synaptic vesicle protein complexes
    • Baldwin MR, Barbieri JT (2007) Association of botulinum neurotoxin serotypes a and B with synaptic vesicle protein complexes. Biochemistry 46: 3200-3210.
    • (2007) Biochemistry , vol.46 , pp. 3200-3210
    • Baldwin, M.R.1    Barbieri, J.T.2
  • 44
    • 0017596090 scopus 로고
    • An antigenic polypeptide fragment isolated from tetanus toxin: Chemical characterization, binding to gangliosides and retrograde axonal transport in various neuron systems
    • Bizzini B, Stoeckel K, Schwab M (1977) An antigenic polypeptide fragment isolated from tetanus toxin: chemical characterization, binding to gangliosides and retrograde axonal transport in various neuron systems. J Neurochem 28: 529-542.
    • (1977) J Neurochem , vol.28 , pp. 529-542
    • Bizzini, B.1    Stoeckel, K.2    Schwab, M.3
  • 45
    • 0018414808 scopus 로고
    • Retrograde transport of tetanus toxin through a chain of two neurons
    • Dumas M, Schwab ME, Baumann R, Thoenen H (1979) Retrograde transport of tetanus toxin through a chain of two neurons. Brain Res 165: 354-357.
    • (1979) Brain Res , vol.165 , pp. 354-357
    • Dumas, M.1    Schwab, M.E.2    Baumann, R.3    Thoenen, H.4
  • 46
    • 0019305421 scopus 로고
    • Interaction of fragments B and C of tetanus toxin with neural and thyroid membranes and with gangliosides
    • Morris NP, Consiglio E, Kohn LD, Habig WH, Hardegree MC, et al. (1980) Interaction of fragments B and C of tetanus toxin with neural and thyroid membranes and with gangliosides. J Biol Chem 255: 6071-6076.
    • (1980) J Biol Chem , vol.255 , pp. 6071-6076
    • Morris, N.P.1    Consiglio, E.2    Kohn, L.D.3    Habig, W.H.4    Hardegree, M.C.5
  • 47
    • 0023028984 scopus 로고
    • Quantitative comparison between tetanus toxin, some fragments and toxoid for binding and axonal transport in the rat
    • Weller U, Taylor CF, Habermann E (1986) Quantitative comparison between tetanus toxin, some fragments and toxoid for binding and axonal transport in the rat. Toxicon 24: 1055-1063.
    • (1986) Toxicon , vol.24 , pp. 1055-1063
    • Weller, U.1    Taylor, C.F.2    Habermann, E.3
  • 48
    • 0027203046 scopus 로고
    • Mutations in human dynamin block an intermediate stage in coated vesicle formation
    • van der Bliek AM, Redelmeier TE, Damke H, Tisdale EJ, Meyerowitz EM, et al. (1993) Mutations in human dynamin block an intermediate stage in coated vesicle formation. J Cell Biol 122: 553-563.
    • (1993) J Cell Biol , vol.122 , pp. 553-563
    • van der, B.A.M.1    Redelmeier, T.E.2    Damke, H.3    Tisdale, E.J.4    Meyerowitz, E.M.5
  • 49
    • 0021237942 scopus 로고
    • The binding fragment from tetanus toxin antagonizes the neuromuscular blocking actions of botulinum toxin
    • Simpson LL (1984) The binding fragment from tetanus toxin antagonizes the neuromuscular blocking actions of botulinum toxin. J Pharmacol Exp Ther 229: 182-187.
    • (1984) J Pharmacol Exp Ther , vol.229 , pp. 182-187
    • Simpson, L.L.1
  • 50
    • 69949182315 scopus 로고    scopus 로고
    • Botulinum neurotoxins C, E and F Bind Gangliosides Via a Conserved Binding Site Prior to Stimulation-dependent Uptake With Botulinum Neurotoxin F Utilising the Three Isoforms of SV2 As Second Receptor
    • Rummel A, Hafner K, Mahrhold S, Darashchonak N, Holt M, et al. (2009) Botulinum neurotoxins C, E and F bind gangliosides via a conserved binding site prior to stimulation-dependent uptake with botulinum neurotoxin F utilising the three isoforms of SV2 as second receptor. J Neurochem 110: 1942-1954.
    • (2009) J Neurochem , vol.110 , pp. 1942-1954
    • Rummel, A.1    Hafner, K.2    Mahrhold, S.3    Darashchonak, N.4    Holt, M.5
  • 52
    • 0033398955 scopus 로고    scopus 로고
    • SV2A and SV2B function as redundant Ca2+ regulators in neurotransmitter release
    • Janz R, Goda Y, Geppert M, Missler M, Sudhof TC (1999) SV2A and SV2B function as redundant Ca2+ regulators in neurotransmitter release. Neuron 24: 1003-1016.
    • (1999) Neuron , vol.24 , pp. 1003-1016
    • Janz, R.1    Goda, Y.2    Geppert, M.3    Missler, M.4    Sudhof, T.C.5
  • 53
    • 0027278599 scopus 로고
    • The SV2 protein of synaptic vesicles is a keratan sulfate proteoglycan
    • Scranton TW, Iwata M, Carlson SS (1993) The SV2 protein of synaptic vesicles is a keratan sulfate proteoglycan. J Neurochem 61: 29-44.
    • (1993) J Neurochem , vol.61 , pp. 29-44
    • Scranton, T.W.1    Iwata, M.2    Carlson, S.S.3
  • 54
    • 0344761960 scopus 로고    scopus 로고
    • SV2C is a synaptic vesicle protein with an unusually restricted localization: Anatomy of a synaptic vesicle protein family
    • Janz R, Sudhof TC (1999) SV2C is a synaptic vesicle protein with an unusually restricted localization: anatomy of a synaptic vesicle protein family. Neuroscience 94: 1279-1290.
    • (1999) Neuroscience , vol.94 , pp. 1279-1290
    • Janz, R.1    Sudhof, T.C.2
  • 55
    • 0026726318 scopus 로고
    • The synaptic vesicle protein SV2 is a novel type of transmembrane transporter
    • Feany MB, Lee S, Edwards RH, Buckley KM (1992) The synaptic vesicle protein SV2 is a novel type of transmembrane transporter. Cell 70: 861-867.
    • (1992) Cell , vol.70 , pp. 861-867
    • Feany, M.B.1    Lee, S.2    Edwards, R.H.3    Buckley, K.M.4
  • 56
    • 0021922503 scopus 로고
    • Identification of a transmembrane glycoprotein specific for secretory vesicles of neural and endocrine cells
    • Buckley K, Kelly RB (1985) Identification of a transmembrane glycoprotein specific for secretory vesicles of neural and endocrine cells. J Cell Biol 100: 1284-1294.
    • (1985) J Cell Biol , vol.100 , pp. 1284-1294
    • Buckley, K.1    Kelly, R.B.2
  • 57
    • 0026786473 scopus 로고
    • SV2, a brain synaptic vesicle protein homologous to bacterial transporters
    • Bajjalieh SM, Peterson K, Shinghal R, Scheller RH (1992) SV2, a brain synaptic vesicle protein homologous to bacterial transporters. Science 257: 1271-1273.
    • (1992) Science , vol.257 , pp. 1271-1273
    • Bajjalieh, S.M.1    Peterson, K.2    Shinghal, R.3    Scheller, R.H.4
  • 58
    • 67649210455 scopus 로고    scopus 로고
    • Glycosylated SV2 and gangliosides as dual receptors for botulinum neurotoxin serotype F
    • Fu Z, Chen C, Barbieri JT, Kim JJ, Baldwin MR (2009) Glycosylated SV2 and gangliosides as dual receptors for botulinum neurotoxin serotype F. Biochemistry 48: 5631-5641.
    • (2009) Biochemistry , vol.48 , pp. 5631-5641
    • Fu, Z.1    Chen, C.2    Barbieri, J.T.3    Kim, J.J.4    Baldwin, M.R.5
  • 59
    • 33746618384 scopus 로고    scopus 로고
    • Tetanus toxin is internalized by a sequential clathrin-dependent mechanism initiated within lipid microdomains and independent of epsin1
    • Deinhardt K, Berninghausen O, Willison HJ, Hopkins CR, Schiavo G (2006) Tetanus toxin is internalized by a sequential clathrin-dependent mechanism initiated within lipid microdomains and independent of epsin1. J Cell Biol 174: 459-471.
    • (2006) J Cell Biol , vol.174 , pp. 459-471
    • Deinhardt, K.1    Berninghausen, O.2    Willison, H.J.3    Hopkins, C.R.4    Schiavo, G.5
  • 60
    • 23644441527 scopus 로고    scopus 로고
    • Internalization of a GFP-tetanus toxin C-terminal fragment fusion protein at mature mouse neuromuscular junctions
    • Roux S, Colasante C, Saint Cloment C, Barbier J, Curie T, et al. (2005) Internalization of a GFP-tetanus toxin C-terminal fragment fusion protein at mature mouse neuromuscular junctions. Mol Cell Neurosci 30: 572-582.
    • (2005) Mol Cell Neurosci , vol.30 , pp. 572-582
    • Roux, S.1    Colasante, C.2    Saint, C.C.3    Barbier, J.4    Curie, T.5
  • 62
    • 0037446837 scopus 로고    scopus 로고
    • GM1-containing lipid rafts are depleted within clathrin-coated pits
    • Nichols BJ (2003) GM1-containing lipid rafts are depleted within clathrin-coated pits. Curr Biol 13: 686-690.
    • (2003) Curr Biol , vol.13 , pp. 686-690
    • Nichols, B.J.1
  • 63
    • 0023048904 scopus 로고
    • Botulinum neurotoxin type B. Its purification, radioiodination and interaction with rat-brain synaptosomal membranes
    • Evans DM, Williams RS, Shone CC, Hambleton P, Melling J, et al. (1986) Botulinum neurotoxin type B. Its purification, radioiodination and interaction with rat-brain synaptosomal membranes. Eur J Biochem 154: 409-416.
    • (1986) Eur J Biochem , vol.154 , pp. 409-416
    • Evans, D.M.1    Williams, R.S.2    Shone, C.C.3    Hambleton, P.4    Melling, J.5
  • 64
    • 0022545876 scopus 로고
    • Purification of type E botulinum neurotoxin by high-performance ion exchange chromatography
    • Schmidt JJ, Siegel LS (1986) Purification of type E botulinum neurotoxin by high-performance ion exchange chromatography. Anal Biochem 156: 213-219.
    • (1986) Anal Biochem , vol.156 , pp. 213-219
    • Schmidt, J.J.1    Siegel, L.S.2
  • 65
    • 70350371732 scopus 로고    scopus 로고
    • Gangliosides as high affinity receptors for tetanus neurotoxin
    • Chen C, Fu Z, Kim JJ, Barbieri JT, Baldwin MR (2009) Gangliosides as high affinity receptors for tetanus neurotoxin. J Biol Chem 284: 26569-26577.
    • (2009) J Biol Chem , vol.284 , pp. 26569-26577
    • Chen, C.1    Fu, Z.2    Kim, J.J.3    Barbieri, J.T.4    Baldwin, M.R.5


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