Commonly used leukotriene B4 receptor antagonists possess intrinsic activity as agonists in human endothelial cells: Effects on calcium transients, adhesive events and mediator release

Prostaglandins Leukotrienes and Essential Fatty Acids

Volumn 84, Issue 3-4, 2011, Pages 109-112

  Johansson, Anne Sofie ^a   Haeggström, Jesper Z ^b   Palmblad, Jan ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Adhesion; BLT; Endothelial cells; Leukotriene; Receptor antagonism

Indexed keywords

1 [3 (4 BIPHENYLYLMETHYL) 4 HYDROXYCHROMAN 7 YL]CYCLOPENTANECARBOXYLIC ACID; 2 (2,6 DIHYDROXYHEXYL) 6 (3 HYDROXY 1,5 UNDECADIENYL)PYRIDINE; 5 ETHYL 2 HYDROXY 4 [6 METHYL 6 (1H TETRAZOL 5 YL)HEPTYLOXY]ACETOPHENONE; CALCIUM; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; INTERCELLULAR ADHESION MOLECULE 1; MONOCYTE CHEMOTACTIC PROTEIN 1; NITRITE; VASCULAR CELL ADHESION MOLECULE 1;

ARTICLE; CALCIUM MOBILIZATION; CALCIUM TRANSPORT; CELL ADHESION; CELL STIMULATION; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EXPOSURE; DRUG POTENCY; HUMAN; HUMAN CELL; IN VITRO STUDY; INCUBATION TIME; MEDIATOR RELEASE; NEUTROPHIL; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; UMBILICAL VEIN ENDOTHELIAL CELL; UPREGULATION;

BENZOPYRANS; CALCIUM; CARBOXYLIC ACIDS; CELL ADHESION; CHEMOKINE CCL2; E-SELECTIN; ENDOTHELIAL CELLS; FATTY ALCOHOLS; GLYCOLS; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; LEUKOTRIENE ANTAGONISTS; NEUTROPHILS; RECEPTORS, LEUKOTRIENE B4; TETRAZOLES; UP-REGULATION; VASCULAR CELL ADHESION MOLECULE-1;

EID: 79151478743     PISSN: 09523278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.plefa.2010.11.003     Document Type: Article

References (20)

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