Efficacy of Caffeic acid Phenethyl Ester (CAPE) in skin B16-F0 melanoma tumor bearing C57BL/6 mice

Investigational New Drugs

Volumn 29, Issue 1, 2011, Pages 52-62

  Kudugunti, Shashi K ^a   Vad, Nikhil M ^a   Ekogbo, Ehi ^a   Moridani, Majid Y ^a  

^a TEXAS TECH UNIVERSITY HEALTH SCIENCES CENTER   (United States)

Author keywords

B16 F0; C57BL 6 mice; Caffeic acid phenethyl ester; CAPE; GSH; Intracellular GSH; Melanoma; Prodrug; Propolis; ROS; Targeted therapy; Tyrosinase

Indexed keywords

ALANINE AMINOTRANSFERASE; CAFFEIC ACID PHENETHYL ESTER; GLUTATHIONE; MALONALDEHYDE; REACTIVE OXYGEN METABOLITE;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; C57BL 6 MOUSE; CANCER INHIBITION; CONTROLLED STUDY; DOSE RESPONSE; DRUG CYTOTOXICITY; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG MECHANISM; IC 50; IN VITRO STUDY; IN VIVO STUDY; KIDNEY HOMOGENATE; LIPID PEROXIDATION; LIVER HOMOGENATE; MALE; MELANOMA B16; MELANOMA CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPLETION; SKIN CANCER; TOXICITY TESTING; TUMOR VOLUME;

ANIMALS; CAFFEIC ACIDS; CELL CYCLE; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; GLUTATHIONE; HYDROGEN-ION CONCENTRATION; INTRACELLULAR SPACE; MALE; MELANOMA, EXPERIMENTAL; MICE; MICE, INBRED C57BL; MONOPHENOL MONOOXYGENASE; OXIDATION-REDUCTION; OXYGEN; PHENYLETHYL ALCOHOL; REACTIVE OXYGEN SPECIES; SKIN NEOPLASMS; SPECTROPHOTOMETRY, ULTRAVIOLET; TREATMENT OUTCOME;

EID: 79151475189     PISSN: 01676997     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10637-009-9334-5     Document Type: Article

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