메뉴 건너뛰기




Volumn 1812, Issue 4, 2011, Pages 447-458

Lipotoxicity and steatohepatitis in an overfed mouse model for non-alcoholic fatty liver disease

Author keywords

Adipose tissue; Endoplasmatic reticulum stress; High fat diet; Liver; Non alcoholic fatty liver disease; Overnutrition; Steatohepatitis

Indexed keywords

ADIPONECTIN; CD36 ANTIGEN; FATTY ACID BINDING PROTEIN; FIBROBLAST GROWTH FACTOR 21; GLYCOGEN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA;

EID: 79151469687     PISSN: 09254439     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbadis.2011.01.003     Document Type: Article
Times cited : (78)

References (53)
  • 1
    • 56549117448 scopus 로고    scopus 로고
    • Animal models of NASH: getting both pathology and metabolic context right
    • Larter C.Z., Yeh M.M. Animal models of NASH: getting both pathology and metabolic context right. J. Gastroenterol. Hepatol. 2008, 23:1635-1648.
    • (2008) J. Gastroenterol. Hepatol. , vol.23 , pp. 1635-1648
    • Larter, C.Z.1    Yeh, M.M.2
  • 2
    • 0025260531 scopus 로고
    • Fatty liver hepatitis (steatohepatitis) and obesity: an autopsy study with analysis of risk factors
    • Wanless I.R., Lentz J.S. Fatty liver hepatitis (steatohepatitis) and obesity: an autopsy study with analysis of risk factors. Hepatology 1990, 12:1106-1110.
    • (1990) Hepatology , vol.12 , pp. 1106-1110
    • Wanless, I.R.1    Lentz, J.S.2
  • 4
    • 0031799747 scopus 로고    scopus 로고
    • Hepatic steatosis: innocent bystander or guilty party?
    • Day C.P., James O.F. Hepatic steatosis: innocent bystander or guilty party?. Hepatology 1998, 27:1463-1466.
    • (1998) Hepatology , vol.27 , pp. 1463-1466
    • Day, C.P.1    James, O.F.2
  • 6
    • 0001513966 scopus 로고    scopus 로고
    • Obesity increases sensitivity to endotoxin liver injury: implications for the pathogenesis of steatohepatitis
    • Yang S.Q., Lin H.Z., Lane M.D., Clemens M., Diehl A.M. Obesity increases sensitivity to endotoxin liver injury: implications for the pathogenesis of steatohepatitis. Proc. Natl. Acad. Sci. U. S. A. 1997, 94:2557-2562.
    • (1997) Proc. Natl. Acad. Sci. U. S. A. , vol.94 , pp. 2557-2562
    • Yang, S.Q.1    Lin, H.Z.2    Lane, M.D.3    Clemens, M.4    Diehl, A.M.5
  • 8
    • 77955690182 scopus 로고    scopus 로고
    • Hepatic lipotoxicity and the pathogenesis of nonalcoholic steatohepatitis: the central role of nontriglyceride fatty acid metabolites
    • Neuschwander-Tetri B.A. Hepatic lipotoxicity and the pathogenesis of nonalcoholic steatohepatitis: the central role of nontriglyceride fatty acid metabolites. Hepatology 2010, 52:774-788.
    • (2010) Hepatology , vol.52 , pp. 774-788
    • Neuschwander-Tetri, B.A.1
  • 9
    • 0027947379 scopus 로고
    • Beta-cell lipotoxicity in the pathogenesis of non-insulin-dependent diabetes mellitus of obese rats: impairment in adipocyte-beta-cell relationships
    • Lee Y., Hirose H., Ohneda M., Johnson J.H., McGarry J.D., Unger R.H. Beta-cell lipotoxicity in the pathogenesis of non-insulin-dependent diabetes mellitus of obese rats: impairment in adipocyte-beta-cell relationships. Proc. Natl. Acad. Sci. U. S. A. 1994, 91:10878-10882.
    • (1994) Proc. Natl. Acad. Sci. U. S. A. , vol.91 , pp. 10878-10882
    • Lee, Y.1    Hirose, H.2    Ohneda, M.3    Johnson, J.H.4    McGarry, J.D.5    Unger, R.H.6
  • 10
    • 56649094325 scopus 로고    scopus 로고
    • Molecular mechanisms of lipotoxicity in nonalcoholic fatty liver disease
    • Malhi H., Gores G.J. Molecular mechanisms of lipotoxicity in nonalcoholic fatty liver disease. Semin. Liver Dis. 2008, 28:360-369.
    • (2008) Semin. Liver Dis. , vol.28 , pp. 360-369
    • Malhi, H.1    Gores, G.J.2
  • 12
    • 18244382304 scopus 로고    scopus 로고
    • Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease
    • Donnelly K.L., Smith C.I., Schwarzenberg S.J., Jessurun J., Boldt M.D., Parks E.J. Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease. J. Clin. Invest. 2005, 115:1343-1351.
    • (2005) J. Clin. Invest. , vol.115 , pp. 1343-1351
    • Donnelly, K.L.1    Smith, C.I.2    Schwarzenberg, S.J.3    Jessurun, J.4    Boldt, M.D.5    Parks, E.J.6
  • 14
    • 57649214103 scopus 로고    scopus 로고
    • Recent insights into hepatic lipid metabolism in non-alcoholic fatty liver disease (NAFLD)
    • Musso G., Gambino R., Cassader M. Recent insights into hepatic lipid metabolism in non-alcoholic fatty liver disease (NAFLD). Prog. Lipid Res. 2009, 48:1-26.
    • (2009) Prog. Lipid Res. , vol.48 , pp. 1-26
    • Musso, G.1    Gambino, R.2    Cassader, M.3
  • 15
    • 70350417312 scopus 로고    scopus 로고
    • Dietary sucrose is essential to the development of liver injury in the methionine-choline-deficient model of steatohepatitis
    • Pickens M.K., Yan J.S., Ng R.K., Ogata H., Grenert J.P., Beysen C., Turner S.M., Maher J.J. Dietary sucrose is essential to the development of liver injury in the methionine-choline-deficient model of steatohepatitis. J. Lipid Res. 2009, 50:2072-2082.
    • (2009) J. Lipid Res. , vol.50 , pp. 2072-2082
    • Pickens, M.K.1    Yan, J.S.2    Ng, R.K.3    Ogata, H.4    Grenert, J.P.5    Beysen, C.6    Turner, S.M.7    Maher, J.J.8
  • 16
    • 56649123256 scopus 로고    scopus 로고
    • The epidemiology of nonalcoholic fatty liver disease: a global perspective
    • Lazo M., Clark J.M. The epidemiology of nonalcoholic fatty liver disease: a global perspective. Semin. Liver Dis. 2008, 28:339-350.
    • (2008) Semin. Liver Dis. , vol.28 , pp. 339-350
    • Lazo, M.1    Clark, J.M.2
  • 18
    • 33644882531 scopus 로고    scopus 로고
    • An improved, single step standardized method of lipid extraction from human skeletal muscle tissue
    • Srivastava N.K., Pradhan S., Mittal B., Kumar R., Gowda G.N. An improved, single step standardized method of lipid extraction from human skeletal muscle tissue. Anal. Lett. 2006, 39:297-315.
    • (2006) Anal. Lett. , vol.39 , pp. 297-315
    • Srivastava, N.K.1    Pradhan, S.2    Mittal, B.3    Kumar, R.4    Gowda, G.N.5
  • 20
    • 30644466345 scopus 로고    scopus 로고
    • Factor correction as a tool to eliminate between-session variation in replicate experiments: application to molecular biology and retrovirology
    • Ruijter J.M., Thygesen H.H., Schoneveld O.J., Das A.T., Berkhout B., Lamers W.H. Factor correction as a tool to eliminate between-session variation in replicate experiments: application to molecular biology and retrovirology. Retrovirology 2006, 3:2.
    • (2006) Retrovirology , vol.3 , pp. 2
    • Ruijter, J.M.1    Thygesen, H.H.2    Schoneveld, O.J.3    Das, A.T.4    Berkhout, B.5    Lamers, W.H.6
  • 21
    • 4043077961 scopus 로고    scopus 로고
    • Molecular mediators of hepatic steatosis and liver injury
    • Browning J.D., Horton J.D. Molecular mediators of hepatic steatosis and liver injury. J. Clin. Invest. 2004, 114:147-152.
    • (2004) J. Clin. Invest. , vol.114 , pp. 147-152
    • Browning, J.D.1    Horton, J.D.2
  • 25
    • 33746536677 scopus 로고    scopus 로고
    • Carbohydrate response element binding protein, ChREBP, a transcription factor coupling hepatic glucose utilization and lipid synthesis
    • Uyeda K., Repa J.J. Carbohydrate response element binding protein, ChREBP, a transcription factor coupling hepatic glucose utilization and lipid synthesis. Cell Metab. 2006, 4:107-110.
    • (2006) Cell Metab. , vol.4 , pp. 107-110
    • Uyeda, K.1    Repa, J.J.2
  • 26
    • 0035190154 scopus 로고    scopus 로고
    • Immunohistochemical detection of myeloperoxidase and its oxidation products in Kupffer cells of human liver
    • Brown K.E., Brunt E.M., Heinecke J.W. Immunohistochemical detection of myeloperoxidase and its oxidation products in Kupffer cells of human liver. Am. J. Pathol. 2001, 159:2081-2088.
    • (2001) Am. J. Pathol. , vol.159 , pp. 2081-2088
    • Brown, K.E.1    Brunt, E.M.2    Heinecke, J.W.3
  • 27
    • 14844288046 scopus 로고    scopus 로고
    • Heme oxygenase-1 levels and oxidative stress-related parameters in non-alcoholic fatty liver disease patients
    • Malaguarnera L., Madeddu R., Palio E., Arena N., Malaguarnera M. Heme oxygenase-1 levels and oxidative stress-related parameters in non-alcoholic fatty liver disease patients. J. Hepatol. 2005, 42:585-591.
    • (2005) J. Hepatol. , vol.42 , pp. 585-591
    • Malaguarnera, L.1    Madeddu, R.2    Palio, E.3    Arena, N.4    Malaguarnera, M.5
  • 29
    • 0031962151 scopus 로고    scopus 로고
    • Hepatic cytochrome P450 2E1 is increased in patients with nonalcoholic steatohepatitis
    • Weltman M.D., Farrell G.C., Hall P., Ingelman-Sundberg M., Liddle C. Hepatic cytochrome P450 2E1 is increased in patients with nonalcoholic steatohepatitis. Hepatology 1998, 27:128-133.
    • (1998) Hepatology , vol.27 , pp. 128-133
    • Weltman, M.D.1    Farrell, G.C.2    Hall, P.3    Ingelman-Sundberg, M.4    Liddle, C.5
  • 30
    • 33750838526 scopus 로고    scopus 로고
    • Heme oxygenase-1 as a potential therapeutic target for hepatoprotection
    • Farombi E.O., Surh Y.J. Heme oxygenase-1 as a potential therapeutic target for hepatoprotection. J. Biochem. Mol. Biol. 2006, 39:479-491.
    • (2006) J. Biochem. Mol. Biol. , vol.39 , pp. 479-491
    • Farombi, E.O.1    Surh, Y.J.2
  • 31
    • 43549105167 scopus 로고    scopus 로고
    • The unfolded protein response: a pathway that links insulin demand with beta-cell failure and diabetes
    • Scheuner D., Kaufman R.J. The unfolded protein response: a pathway that links insulin demand with beta-cell failure and diabetes. Endocr. Rev. 2008, 29:317-333.
    • (2008) Endocr. Rev. , vol.29 , pp. 317-333
    • Scheuner, D.1    Kaufman, R.J.2
  • 34
    • 38349125024 scopus 로고    scopus 로고
    • A new model for nonalcoholic steatohepatitis in the rat utilizing total enteral nutrition to overfeed a high-polyunsaturated fat diet
    • Baumgardner J.N., Shankar K., Hennings L., Badger T.M., Ronis M.J. A new model for nonalcoholic steatohepatitis in the rat utilizing total enteral nutrition to overfeed a high-polyunsaturated fat diet. Am. J. Physiol. Gastrointest. Liver Physiol. 2008, 294:G27-G38.
    • (2008) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.294
    • Baumgardner, J.N.1    Shankar, K.2    Hennings, L.3    Badger, T.M.4    Ronis, M.J.5
  • 39
    • 0033695790 scopus 로고    scopus 로고
    • Up-regulation of peroxisome proliferator-activated receptors (PPAR-alpha) and PPAR-gamma messenger ribonucleic acid expression in the liver in murine obesity: troglitazone induces expression of PPAR-gamma-responsive adipose tissue-specific genes in the liver of obese diabetic mice
    • Memon R.A., Tecott L.H., Nonogaki K., Beigneux A., Moser A.H., Grunfeld C., Feingold K.R. Up-regulation of peroxisome proliferator-activated receptors (PPAR-alpha) and PPAR-gamma messenger ribonucleic acid expression in the liver in murine obesity: troglitazone induces expression of PPAR-gamma-responsive adipose tissue-specific genes in the liver of obese diabetic mice. Endocrinology 2000, 141:4021-4031.
    • (2000) Endocrinology , vol.141 , pp. 4021-4031
    • Memon, R.A.1    Tecott, L.H.2    Nonogaki, K.3    Beigneux, A.4    Moser, A.H.5    Grunfeld, C.6    Feingold, K.R.7
  • 40
    • 35748972366 scopus 로고    scopus 로고
    • Genes involved in fatty acid partitioning and binding, lipolysis, monocyte/macrophage recruitment, and inflammation are overexpressed in the human fatty liver of insulin-resistant subjects
    • Westerbacka J., Kolak M., Kiviluoto T., Arkkila P., Siren J., Hamsten A., Fisher R.M., Yki-Jarvinen H. Genes involved in fatty acid partitioning and binding, lipolysis, monocyte/macrophage recruitment, and inflammation are overexpressed in the human fatty liver of insulin-resistant subjects. Diabetes 2007, 56:2759-2765.
    • (2007) Diabetes , vol.56 , pp. 2759-2765
    • Westerbacka, J.1    Kolak, M.2    Kiviluoto, T.3    Arkkila, P.4    Siren, J.5    Hamsten, A.6    Fisher, R.M.7    Yki-Jarvinen, H.8
  • 41
    • 37549052177 scopus 로고    scopus 로고
    • Identification of a domain within peroxisome proliferator-activated receptor gamma regulating expression of a group of genes containing fibroblast growth factor 21 that are selectively repressed by SIRT1 in adipocytes
    • Wang H., Qiang L., Farmer S.R. Identification of a domain within peroxisome proliferator-activated receptor gamma regulating expression of a group of genes containing fibroblast growth factor 21 that are selectively repressed by SIRT1 in adipocytes. Mol. Cell. Biol. 2008, 28:188-200.
    • (2008) Mol. Cell. Biol. , vol.28 , pp. 188-200
    • Wang, H.1    Qiang, L.2    Farmer, S.R.3
  • 43
    • 33644955272 scopus 로고    scopus 로고
    • Mouse models in non-alcoholic fatty liver disease and steatohepatitis research
    • Anstee Q.M., Goldin R.D. Mouse models in non-alcoholic fatty liver disease and steatohepatitis research. Int. J. Exp. Pathol. 2006, 87:1-16.
    • (2006) Int. J. Exp. Pathol. , vol.87 , pp. 1-16
    • Anstee, Q.M.1    Goldin, R.D.2
  • 46
    • 36048950218 scopus 로고    scopus 로고
    • Adipogenesis and lipotoxicity: role of peroxisome proliferator-activated receptor gamma (PPARgamma) and PPARgammacoactivator-1 (PGC1)
    • Medina-Gomez G., Gray S., Vidal-Puig A. Adipogenesis and lipotoxicity: role of peroxisome proliferator-activated receptor gamma (PPARgamma) and PPARgammacoactivator-1 (PGC1). Public Health Nutr. 2007, 10:1132-1137.
    • (2007) Public Health Nutr. , vol.10 , pp. 1132-1137
    • Medina-Gomez, G.1    Gray, S.2    Vidal-Puig, A.3
  • 48
    • 44949190713 scopus 로고    scopus 로고
    • VAT fat is bad for the liver, SAT fat is not!
    • Fan J.G., Farrell G.C. VAT fat is bad for the liver, SAT fat is not!. J. Gastroenterol. Hepatol. 2008, 23:829-832.
    • (2008) J. Gastroenterol. Hepatol. , vol.23 , pp. 829-832
    • Fan, J.G.1    Farrell, G.C.2
  • 49
    • 33645815074 scopus 로고    scopus 로고
    • Autocrine tumor necrosis factor alpha links endoplasmic reticulum stress to the membrane death receptor pathway through IRE1alpha-mediated NF-kappaB activation and down-regulation of TRAF2 expression
    • Hu P., Han Z., Couvillon A.D., Kaufman R.J., Exton J.H. Autocrine tumor necrosis factor alpha links endoplasmic reticulum stress to the membrane death receptor pathway through IRE1alpha-mediated NF-kappaB activation and down-regulation of TRAF2 expression. Mol. Cell. Biol. 2006, 26:3071-3084.
    • (2006) Mol. Cell. Biol. , vol.26 , pp. 3071-3084
    • Hu, P.1    Han, Z.2    Couvillon, A.D.3    Kaufman, R.J.4    Exton, J.H.5
  • 50
    • 30944451788 scopus 로고    scopus 로고
    • Saturated fatty acids promote endoplasmic reticulum stress and liver injury in rats with hepatic steatosis
    • Wang D., Wei Y., Pagliassotti M.J. Saturated fatty acids promote endoplasmic reticulum stress and liver injury in rats with hepatic steatosis. Endocrinology 2006, 147:943-951.
    • (2006) Endocrinology , vol.147 , pp. 943-951
    • Wang, D.1    Wei, Y.2    Pagliassotti, M.J.3
  • 52
    • 50549202600 scopus 로고
    • The glucose fatty-acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus
    • Randle P.J., Garland P.B., Hales C.N., Newsholme E.A. The glucose fatty-acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus. Lancet 1963, 1:785-789.
    • (1963) Lancet , vol.1 , pp. 785-789
    • Randle, P.J.1    Garland, P.B.2    Hales, C.N.3    Newsholme, E.A.4
  • 53
    • 6944222621 scopus 로고    scopus 로고
    • Effects of dietary fatty acids on insulin sensitivity and secretion
    • Manco M., Calvani M., Mingrone G. Effects of dietary fatty acids on insulin sensitivity and secretion. Diabetes Obes. Metab. 2004, 6:402-413.
    • (2004) Diabetes Obes. Metab. , vol.6 , pp. 402-413
    • Manco, M.1    Calvani, M.2    Mingrone, G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.