Possible roles of exceptionally conserved residues around the selectivity filters of sodium and calcium channels

Journal of Biological Chemistry

Volumn 286, Issue 4, 2011, Pages 2998-3006

  Tikhonov, Denis B ^a,b   Zhorov, Boris S ^a,b  

^a MCMASTER UNIVERSITY   (Canada)

^b SECHENOV INSTITUTE OF EVOLUTIONARY PHYSIOLOGY AND BIOCHEMISTRY   (Russian Federation)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTATES; CALCIUM CHANNELS; CALCIUM IONS; CONSERVED RESIDUES; EXPERIMENTAL DATA; FILTER RINGS; GLYCINE RESIDUES; H-BONDS; HOMOLOGY MODELS; INTER-DOMAIN; NEW MODEL; POLAR RESIDUES; PORE REGION; POTASSIUM CHANNELS; SELECTIVITY FILTER; STRUCTURAL STABILITIES; TIKHONOV; X-RAY STRUCTURE;

CALCIUM; CARBOXYLATION; IONS; STABILITY;

AMINO ACIDS;

CALCIUM CHANNEL; SODIUM CHANNEL; SODIUM CHANNEL NAV1.4;

ALGORITHM; AMINO ACID SEQUENCE; ARTICLE; BINDING SITE; CONTROLLED STUDY; HYDROGEN BOND; HYDROPHOBICITY; MOLECULAR MODEL; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN STABILITY; PROTEIN STRUCTURE; REPOLARIZATION; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY;

ANIMALS; CALCIUM CHANNELS, L-TYPE; CRYSTALLOGRAPHY, X-RAY; DRUG RESISTANCE; EVOLUTION, MOLECULAR; HUMANS; HYDROGEN BONDING; MODELS, MOLECULAR; MUSCLE PROTEINS; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; SNAKES; SODIUM CHANNELS; TETRODOTOXIN;

SERPENTES;

EID: 78951495901     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.175406     Document Type: Article

References (38)

1. Dudley, S. C., Jr., Chang, N., Hall, J., Lipkind, G., Fozzard, H. A., and French, R. J. (2000) J. Gen. Physiol. 116, 679-690
2. Bruhova, I., and Zhorov, B. S. (2010) J. Gen. Physiol. 135, 261-274
3. Zhorov, B. S., and Tikhonov, D. B. (2004) J. Neurochem. 88, 782-799
4. Lipkind, G. M., and Fozzard, H. A. (1994) Biophys. J. 66, 1-13
5. Tikhonov, D. B., and Zhorov, B. S. (2005) Biophys. J. 88, 184-197
6. Cheng, R. C., Tikhonov, D. B., and Zhorov, B. S. (2010) Eur. Biophys J. 39, 839-853
7. Zhorov, B. S., Folkman, E. V., and Ananthanarayanan, V. S. (2001) Arch. Biochem. Biophys. 393, 22-41
8. Durell, S. R., and Guy, H. R. (2001) Biochem. Biophys. Res. Commun. 281, 741-746
9. Tikhonov, D. B., and Zhorov, B. S. (2007) Biophys. J. 93, 1557-1570
10. Weiner, S. J., Kollman, P. A., Case, D. A., Singh, U. C., Ghio, C., Alagona, G., Profeta, S., and Weiner, P. (1984) J. Am. Chem. Soc. 106, 765-784
11. Weiner, S. J., Kollman, P. A., Nguyen, D. T., and Case, D. A. (1986) J. Comput. Chem. 7, 230-252
12. Lazaridis, T., and Karplus, M. (1999) Proteins 35, 133-152
13. Dewar, M. J., Zoebisch, E. G., Healy, E. F., and Stewart, J. J. (1985) J. Amer. Chem. Soc. 107, 3902-3909
14. Li, Z., and Scheraga, H. A. (1987) Proc. Natl. Acad. Sci. U. S. A. 84, 6611-6615
15. Bruhova, I., Tikhonov, D. B., and Zhorov, B. S. (2008) Mol. Pharmacol. 74, 1033-1045
16. Hille, B. (2001) Ion Channels of Excitable Membranes, Sinauer Associates Inc., Sunderland, MA
17. Struyk, A. F., and Cannon, S. C. (2002) J. Gen. Physiol. 120, 509-516
18. Xiong, W., Li, R. A., Tian, Y., and Tomaselli, G. F. (2003) J. Gen. Physiol. 122, 323-332
19. Tsushima, R. G., Li, R. A., and Backx, P. H. (1997) J. Gen. Physiol. 109, 463-475
20. Tsang, S. Y., Tsushima, R. G., Tomaselli, G. F., Li, R. A., and Backx, P. H. (2005) Mol. Pharmacol. 67, 424-434
21. Carbonneau, E., Vijayaragavan, K., and Chahine, M. (2002) Pflugers Arch. 445, 18-24
22. Santarelli, V. P., Eastwood, A. L., Dougherty, D. A., Horn, R., and Ahern, C. A. (2007) J. Biol. Chem. 282, 8044-8051
23. Chen, L. Q., Chahine, M., Kallen, R. G., Barchi, R. L., and Horn, R. (1992) FEBS Letts. 309, 253-257
24. Backx, P. H., Yue, D. T., Lawrence, J. H., Marban, E., and Tomaselli, G. F. (1992) Science 257, 248-251
25. Satin, J., Kyle, J. W., Chen, M., Bell, P., Cribbs, L. L., Fozzard, H. A., and Rogart, R. B. (1992) Science 256, 1202-1205
26. Geffeney, S. L., Fujimoto, E., Brodie, E. D., 3rd, Brodie, E. D., Jr., and Ruben, P. C. (2005) Nature 434, 759-763
27. Yamagishi, T., Li, R. A., Hsu, K., Marbán, E., and Tomaselli, G. F. (2001) J. Gen. Physiol. 118, 171-182
28. Santarelli, V. P., Eastwood, A. L., Dougherty, D. A., Ahern, C. A., and Horn, R. (2007) Biophys. J. 93, 2341-2349
29. McPhalen, C. A., Strynadka, N. C., and James, M. N. (1991) Adv. Protein Chem. 42, 77-144
30. Ikeda, T., Boero, M., and Terakura, K. (2007) J. Chem. Physics 127, 074503-1-074503-8
31. Cheng, R. C., and Zhorov, B. S. (2010) Eur. Biophys. J. 39, 825-838
32. Chahine, M., Chen, L. Q., Kallen, R. G., Barchi, R. L., and Horn, R. (1992) Biophys. J. 62, 37-40
33. Heinemann, S. H., Terlau, H., Stühmer, W., Imoto, K., and Numa, S. (1992) Nature 356, 441-443
34. Tang, S., Mikala, G., Bahinski, A., Yatani, A., Varadi, G., and Schwartz, A. (1993) J. Biol. Chem. 268, 13026-13029
35. Ren, D., Navarro, B., Xu, H., Yue, L., Shi, Q., and Clapham, D. E. (2001) Science 294, 2372-2375
36. Yue, L., Navarro, B., Ren, D., Ramos, A., and Clapham, D. E. (2002) J. Gen. Physiol. 120, 845-853
37. Zhang, M. M., McArthur, J. R., Azam, L., Bulaj, G., Olivera, B. M., French, R. J., and Yoshikami, D. (2009) Channels 3, 32-38
38. Garden, D. P., and Zhorov, B. S. (2010) J. Computer-aided Mol. Design 24, 91-105