Norovirus in the hospital setting: Virus introduction and spread within the hospital environment

Journal of Hospital Infection

Volumn 77, Issue 2, 2011, Pages 106-112

  Morter, S ^a   Bennet, G ^a   Fish, J ^a   Richards, J ^a   Allen, D J ^b   Nawaz, S ^b   Iturriza Gomara M ^b   Brolly, S ^a   Gray, J ^a  

^a NORFOLK AND NORWICH UNIVERSITY HOSPITAL   (United Kingdom)

^b PUBLIC HEALTH ENGLAND   (United Kingdom)

Author keywords

Environmental contamination; Genetic variants; Norovirus; Virus introduction

Indexed keywords

ARTICLE; GASTROENTERITIS; GENE CLUSTER; GENOTYPE; HOSPITAL EQUIPMENT; HOSPITAL HYGIENE; HOSPITAL INFECTION; NONHUMAN; NOROVIRUS; VIRAL CONTAMINATION; VIRUS CHARACTERIZATION; VIRUS STRAIN;

CALICIVIRIDAE INFECTIONS; CROSS INFECTION; EQUIPMENT CONTAMINATION; GENOTYPE; HOSPITALS; HUMANS; INFECTION CONTROL; NOROVIRUS;

EID: 78951489303     PISSN: 01956701     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhin.2010.09.035     Document Type: Article

References (22)

1. Gallimore C.I., Green J., Lewis D., et al. Diversity of noroviruses co-circulating in the north of England from 1998 to 2001. J Clin Microbiol 2004, 42:1396-1401.
2. Parashar U.D., Dow L., Frankhauser R.L., et al. An outbreak of viral gastroenteritis associated with the consumption of sandwiches: implications for the control of transmission by food handlers. Epidemiol Infect 1998, 121:615-621.
3. Ho M., Munroe S.S., Stine S., et al. Viral gastroenteritis aboard a cruise ship. Lancet 1989, ii:961-965.
4. Evans M.R., Meldrum R., Lane W., et al. An outbreak of viral gastroenteritis following environmental contamination at a concert hall. Epidemiol Infect 2002, 129:355-360.
5. Kobayashi S., Morishita T., Yamashita T., et al. A large outbreak of gastroenteritis associated with a small round structured virus among schoolchildren and teachers in Japan. Epidemiol Infect 1991, 116:940-948.
6. Allen D.J., Gray J.J., Gallimore C.I., Xerry J., Iturriza-Gómara M. Analysis of amino acid variation in the P2 domain of the GII-4 norovirus VP1 protein reveals putative variant-specific epitopes. PLoS One 2008, 3:e1485.
7. Lopman B.A., Reacher M.H., Vipond I.B., Sarangi J., Brown D.W.G. Clinical manifestation of norovirus gastroenteritis in health care settings. CID 2004, 39:318-324.
8. Harris J.P., Edmunds W.J., Pebody R., Brown D.W., Lopman B.A. Deaths from norovirus among the elderly, England and Wales. Emerg Infect Dis 2008, 14:1546-1552.
9. Roddie C., Paul J.P.V., Benjamin R., et al. Allogenic hematopoietic stem cell transplantation and norovirus gastroenteritis: a previously unrecognised cause of morbidity. Clin Infect Dis 2009, 49:1061-1068.
10. Amar C.F.L., East C.L., Gray J., Iturriza-Gomara M., Maclure E.A., McLauchlin J. Detection by PCR of eight groups of enteric pathogens in 4627 faecal samples: re-examination of the English case-control infectious intestinal disease study (1993-1996). Eur J Clin Microbiol Infect Dis 2007, 26:311-323.
11. Lopman B.A., Andrews N., Sarangi J., Vipond I.B., Brown D.W.G., Reacher M.H. Institutional risk factors for outbreaks of nosocomial gastroenteritis: survival analysis of a cohort of hospital units in South-west England, 2002-2003. J Hosp Infect 2005, 60:135-143.
12. Chadwick P.R., Beards G., Brown D., et al. Management of hospital outbreaks of gastroenteritis due to small round structured viruses. J Hosp Infect 2000, 45:1-10.
13. Harris J.P., Lopman B.A., O'Brien S.J. Infection control measures for norovirus: a systematic review of outbreaks in semi-closed settings. J Hosp Infect 2010, 74:1-9.
14. Xerry J., Gallimore C.I., Iturriza-Gómara M., Allen D.J., Gray J.J. Transmission events within outbreaks of gastroenteritis determined through analysis of nucleotide sequences of the P2 domain of genogroup II noroviruses. J Clin Microbiol 2008, 46:947-953.
15. Rolfe K.J., Parmar S., Mururi D., Wreghitt T.G. An internally controlled, one-step, real-time RT-PCR assay for norovirus detection and genogrouping. J Clin Virol 2007, 39:318-321.
16. Kageyama T., Kojima S., Shinohara M., et al. Broadly reactive and highly sensitive assay for Norwalk-like viruses based on real-time quantitative reverse transcription-PCR. J Clin Microbiol 2003, 41:1548-1557.
17. Gallimore C.I., Iturriza-Gomara M., Xerry J., Adigwe J., Gray J.J. Inter-seasonal diversity of norovirus genotypes: emergence and selection of virus variants. Arch Virol 2007, 152:1295-1303.
18. Xerry J., Gallimore C., Iturriza Gomara M., Gray J. Tracking the transmission routes of genogroup II noroviruses in suspected foodborne or environmental outbreaks of gastroenteritis through sequence analysis of the P2 domain. J Med Virol 2009, 81:1298-1304.
19. Gallimore C.I., Taylor C., Gennery A.R., et al. Use of a heminested reverse transcriptase PCR assay for detection of astrovirus in environmental swabs from an outbreak of gastroenteritis in a pediatric primary immunodeficiency unit. J Clin Microbiol 2005, 43:3890-3894.
20. Lopman B.A., Reacher M.H., Vipond I.B., et al. Epidemiology and cost of nosocomial gastroenteritis, Avon, England, 2002-2003. Emerg Infect Dis 2004, 10:1827-1834.
21. Lindesmith L.C., Donaldson E.F., Lobue A.D., et al. Mechanisms of GII.4 norovirus persistence in human populations. PLoS Med 2008, e31.
22. Siebenga J.J., Vennema H., Renckens B., et al. Epochal evolution of GGII.4 norovirus capsid proteins from 1995 to 2006. J Virol 2007, 81:9932-9941.