Sex-based differences in clinical and angiographic outcomes in patients with st-elevation myocardial infarction treated with concomitant use of glycoprotein iib/iiia inhibitors

Cardiology Journal

Volumn 17, Issue 6, 2010, Pages 580-586

  Kralev, Stefan ^a   Hennig, Oliver ^a   Lang, Siegfried ^a   Kälsch, Thorsten ^a   Borggrefe, Martin ^a   Dempfle, Carl Erik ^a   Süselbeck, Tim ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Acute coronary syndrome; Gender; Gp iib iiia; Myocardial infarction; Stemi

Indexed keywords

ABCIXIMAB; ACETYLSALICYLIC ACID; C REACTIVE PROTEIN; CLOPIDOGREL; EPTIFIBATIDE; HEPARIN; TIROFIBAN;

ADULT; AGE; AGED; ANGIOCARDIOGRAPHY; ARTICLE; BARE METAL STENT; CARDIOGENIC SHOCK; CARDIOVASCULAR RISK; CONTROLLED CLINICAL TRIAL; CORONARY ARTERY BYPASS GRAFT; DEATH; DRUG USE; FEMALE; HEART MUSCLE REVASCULARIZATION; HUMAN; HYPERTENSION; IMPLANTATION; LOADING DRUG DOSE; MAJOR CLINICAL STUDY; MALE; PERCUTANEOUS CORONARY INTERVENTION; PREDICTION; PROSPECTIVE STUDY; REPEATED DRUG DOSE; SEX DIFFERENCE; ST SEGMENT ELEVATION MYOCARDIAL INFARCTION; THROMBOCYTE COUNT; TREATMENT OUTCOME;

AGED; ANGIOPLASTY, BALLOON, CORONARY; CARDIOVASCULAR DISEASES; CHI-SQUARE DISTRIBUTION; CORONARY ANGIOGRAPHY; FEMALE; GERMANY; HOSPITAL MORTALITY; HUMANS; KAPLAN-MEIER ESTIMATE; LOGISTIC MODELS; MALE; METALS; MIDDLE AGED; MYOCARDIAL INFARCTION; PLATELET AGGREGATION INHIBITORS; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; PROSPECTIVE STUDIES; PROSTHESIS DESIGN; RISK ASSESSMENT; RISK FACTORS; SEX FACTORS; STENTS; TIME FACTORS; TREATMENT OUTCOME;

EID: 78951488198     PISSN: 18975593     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. Heart Disease and Stroke Statistics, 2003 Update. American Heart Association, Dallas, TX 2002.
2. Vaccarino V, Krumholz HM, Berkman LF, Horwitz RI. Sex differences in mortality after myocardial infarction: Is there evidence for an increased risk for women? Circulation, 1995; 91: 1861-1871.
3. Greenland P, Reicher-Reiss H, Goldbourt U, Behar S; the Israeli SPRINT Investigators. In-hospital and 1-year mortality in 1524 women after myocardial infarction. Circulation, 1991; 83: 484-491.
4. Fiebach HN, Viscoli CM, Horwitz RI. Differences between women and men in survival after myocardial infarction: Biology or methodology? JAMA, 1990; 263: 1092-1096.
5. Weaver WD, White HD, Wilcox RG. Comparisons of characteristics and outcomes among women and men with acute myocardial infarction treated with thrombolytic therapy: GUSTO-I investigators. JAMA, 1996; 275: 777-782.
6. Malacrida R, Genoni M, Maggioni AP. A comparison of the early outcome of acute myocardial infarction in women and men: The Third International Study of Infarct Survival Collaborative Group. N Engl J Med, 1998; 338: 8-14.
7. Vaccarino V, Parsons L, Every NR et al. Sex-based differences in early mortality after myocardial infarction. National Registry of Myocardial Infarction 2 Participants. N Engl J Med, 1999; 341: 217-225.
8. Vakili BA, Kaplan RC, Brown DL. Sex-based differences in early mortality of patients undergoing primary angioplasty for first acute myocardial infarction. Circulation, 2001; 104: 3034-3038.
9. Antoniucci D, Valenti R, Moschi G et al. Sex-based differences in clinical and angiographic outcomes after primary angioplasty or stenting for acute myocardial infarction. Am J Cardiol, 2001; 87: 289-293.
10. Brodie BR. Why is mortality rate after percutaneous transluminal coronary angioplasty higher in women? Am Heart J, 1999; 137: 582-584.
11. Vacek JL, Rosamond TL, Kramer PH et al. Sex-related differences in patients undergoing direct angioplasty for acute myocardial infarction. Am Heart J, 1993; 126: 521-525.
12. Mehilli J, Kastrati A, Dirschinger J et al. Sex-based analysis of outcome in patients with acute myocardial infarction treated predominantly with percutaneous coronary intervention. JAMA, 2002; 287: 210-215.
13. Antman EM, Hand M, Armstrong PW et al. 2007 Focused update of the ACC/AHA 2004 Guidelines for the management of patients with ST-elevation myocardial infarction. Circulation, 2008; 117: 296-329.
14. The TIMI Study Group. The Thrombolysis in Myocardial Infarction (TIMI) trial: Phase I findings. N Engl J Med, 1985; 312: 932-936.
15. Cannon CP, Weintraub WS, Demopoulos LA et al. For the TACTICS-Thrombolysis in Myocardial Infarction-18 investigators. Comparison of early invasive and conservative strategies in patients with unstable coronary syndromes treated with the glycoprotein IIb/IIIa inhibitor tirofiban. N Engl J Med, 2001; 344: 1879-1897.
16. Lagerqvist B, Safstrom K, Stahle E et al. For the FRISC II Study Group Investigators. Is early invasive treatment of unstable coronary artery disease equally effective for both women and men? J Am Coll Cardiol, 2001; 38: 41-48.
17. Clayton TC, Henderson RA, Poole-Wilson PA et al. Do men benefit more than women from an interventional strategy in patients with unstable angina or non-ST-elevation myocardial infarction? The impact of gender in the RITA 3 trial. Eur Heart J, 2004; 25: 1641-1650.
18. De Luca G, Suryapranata H, Dambrink JH et al. Sex-related differences in outcome after ST-segment elevation myocardial infarction treated by primary angioplasty: Data from the Zwolle Myocardial Infarction study. Am Heart J, 2004; 148: 852-856.
19. Bhatt DL, Topol EJ. Current role of platelet glycoprotein IIb/IIIa inhibitors in acute coronary syndromes. JAMA, 2000; 284: 1549-1558.
20. Chan AW, Chew DP, Bhatt LD et al. Long-term mortality benefit with the combination of stents and abciximab for cardiogenic shock complicating acute myocardial infarction. Am J Cardiol, 2002; 89: 132-136.
21. Ault KA, Cannon CP, Mitchell J et al. Platelet activation in patients after an acute coronary syndrome: Results from the TIMI-12 trial. J Am Coll Cardiol, 1999; 33: 634-639.
22. Mazzone A, De Servi S, Mazzucchelli I et al. Increased concentrations of inflammatory mediators in unstable angina: Correlation with serum troponin T. Heart, 2001; 85: 571-575.
23. Frossard M, Fuchs I, Leitner JM et al. Platelet function predicts myocardial damage in patients with acute myocardial infarction. Circulation, 2004; 110:1392-1397.
24. Gurbel PA, Bliden KP, Zaman KA et al. Clopidogrel loading with eptifibatide to arrest the reactivity of platelets: results of the Clopidogrel Loading With Eptifibatide to Arrest the Reactivity of Platelets (CLEAR PLATELETS) study. Circulation, 2005; 111: 1153-1159.
25. Furman MI, Krueger LA, Linden MD et al. GPIIbIIIa antagonists reduce thromboinflammatory processes in patients with acute coronary syndromes undergoing percutaneous coronary intervention. J Thromb Haemost, 2005; 3: 312-320.
26. Kereiakes DJ. Adjunctive pharmacotherapy before percutaneous coronary intervention in non-ST-elevation acute coronary syndromes: The role of modulating inflammation. Circulation, 2003; 108: III22-III27.
27. Mosucci M, Fox KA, Cannon CP et al. Predictors of major bleeding in acute coronary syndromes: The Global Registry of Acute Coronary Events (GRACE). Eur Heart J, 2003; 24: 1815-1823.