Limited knowledge of lipid rescue therapy in local anaesthetic systemic toxicity

Danish Medical Bulletin

Volumn 58, Issue 1, 2011, Pages

  Jensen Gadegaard, Peter ^a   Skjønnemand, Martin ^a   Damgaard Jensen, Jens ^a   Gottschau, Bo ^a  

^a GENTOFTE UNIVERSITY HOSPITAL   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

INTRALIPID; LIPID; LIPID EMULSION;

ARTICLE; CLINICAL ARTICLE; DENMARK; DRUG EFFICACY; DRUG INTOXICATION; HEART ARREST; HUMAN; LOCAL ANAESTHETIC SYSTEMIC TOXICITY; LOCAL ANESTHESIA; MULTICENTER STUDY; QUESTIONNAIRE; TELEPHONE; TREATMENT RESPONSE; ATTITUDE TO HEALTH; CHEMICALLY INDUCED DISORDER; CLINICAL PRACTICE; HEALTH CARE SURVEY; STATISTICS;

ANESTHESIA, LOCAL; DENMARK; FAT EMULSIONS, INTRAVENOUS; HEALTH CARE SURVEYS; HEALTH KNOWLEDGE, ATTITUDES, PRACTICE; HEART ARREST; HUMANS; LIPIDS; PHYSICIAN'S PRACTICE PATTERNS; QUESTIONNAIRES;

EID: 78951470532     PISSN: 16039629     EISSN: 16039629     Source Type: Journal    
DOI: None     Document Type: Article

References (11)

1. Weinberg GL. Pretreatment or resuscitation with a lipid infusion shifts the dose-response to bupivacaine-induced asystole in rats. Anesthesiology 1998;88:1071-1075.
2. Weinberg GL, Ripper R, Feinstein DL et al. Lipid emulsion infusion rescues dogs from bupicavaine-induced cardiac toxicity. Reg Anesth Pain Med 2003;28:1998-2002.
3. Rosenblatt MA, Abel M, Fischer GE et al. Successful use of a 20% lipid emulsion to resuscitate a patient after presumed bupivacaine-related cardiac arrest. Anesthesiology 2006;105:217-218.
4. Litz RJ, Popp M, Stehr SN et al. Successful resuscitation of a patient with ropivacaine-induced asystole after axillary plexus block using lipid infusion. Anaesthesia 2006;61:800-801.
5. Warren JA, Thoma RB, Georgescu A et al. Intravenous lipid infusion in the successful resuscitation of local anesthetic induces cardiovascular collapse after supraclavicular brachial plexus block. Anesth Analg 2008;106:1578-1580.
6. Spence AG. Lipid reversal of central nervous system symptoms of bupivacain toxicity. Anesthesiology 2007;107:516-517.
7. http://www.aagbi.org/publications/guidelines/docs/latoxicity07.pdf (2 July 2010).
8. http://lipidrescue.squarespace.com/post-your-cases/post/633455 (2 July 2010).
9. Harvey M, Cave G, Kazemi A. Intralipid infusion diminishes return of spontaneous circulation after hypoxic cardiac arrest in rabbits. Anest Analg 2009;108:1163-8.
10. Hamann P, Dargan PI, Parbat N et al. Availability of and use of Intralipid (lipid rescue therapy, lipid emulsion) in England and Wales. Emerg Med J doi:10.1136/emj.2009.083352.
11. Picard J, Ward SC, Zumpe R et al. Guidelines and the adoption of ''lipid rescue'' therapy for local anaesthetic toxicity. Anaesthesia 2009;64:122e5.