Triclosan affects thyroid hormone-dependent metamorphosis in anurans

Toxicological Sciences

Volumn 119, Issue 2, 2011, Pages 417-418

  Helbing, Caren C ^a   van Aggelen, Graham ^b   Veldhoen, Nik ^a  

^a UNIVERSITY OF VICTORIA   (Canada)

^b ENVIRONMENT CANADA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

THYROID HORMONE; THYROID HORMONE RECEPTOR BETA; TRICLOSAN;

BULLFROG; CHI SQUARE TEST; LARVAL DEVELOPMENT; LETTER; METAMORPHOSIS; NONHUMAN; XENOPUS LAEVIS;

ANURA;

EID: 78751699055     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfq343     Document Type: Letter

References (5)

1. Fort, D., Rogers, R., Gorsuch, J., Navarro, L., Peter, R., and Plautz, J. (2010). Triclosan and anuran metamorphosis: no effect on thyroid-mediated metamorphosis in Xenopus laevis. Toxicol. Sci. 113, 392-400.
2. Nieuwkoop, P. D., and Faber, F. (1994). In Normal Table of Xenopus laevis. Garland Publishing, New York.
3. Veldhoen, N., Skirrow, R., Osachoff, H., Wigmore, H., Clapson, D., Gunderson, M., van Aggelen, G., and Helbing, C. (2006). The bactericidal agent triclosan modulates thyroid hormone-associated gene expression and disrupts postembryonic anuran development. Aquat. Toxicol. 80, 217-227.
4. Wagner, M., and Helbing, C. (2005). Multiple variants of the ING1 and ING2 tumor suppressors are differentially expressed and thyroid hormoneresponsive in Xenopus laevis. Gen. Comp. Endocrinol. 144, 38-50.
5. Welshons, W., Thayer, K., Judy, B., Taylor, J., Curran, E., and vom Saal, F. (2003). Large effects from small exposures. I. Mechanisms for endocrinedisrupting chemicals with estrogenic activity. Environ. Health Perspect. 111, 994-1006.