Treatment with carnitine, acetyl carnitine, L-arginine and ginseng improves sperm motility and sexual health in men with asthenopermia;Il trattamento con carnitina, acetilcarnitina, L-arginina e ginseng migliora la motilità spermatica e la salute sessuale negli uomini con astenozoospermia

Minerva Urologica e Nefrologica

Volumn 62, Issue 3, 2010, Pages 213-218

  Morgante, G ^a   Scolaro, V ^a   Tosti, C ^a   Di Sabatino, A ^a   Piomboni, P ^a   De Leo, V ^a  

^a UNIVERSITY OF SIENA   (Italy)

Author keywords

Infertility, male; Sexual dysfunction, physiological; Sperm motility

Indexed keywords

ACETYLCARNITINE; ARGININE; GINSENG EXTRACT;

ARTICLE; ASTHENOSPERMIA; DRUG EFFICACY; GINSENG; HUMAN; LIBIDO; MAJOR CLINICAL STUDY; MALE; MALE INFERTILITY; RANDOMIZED CONTROLLED TRIAL; SEXUAL DYSFUNCTION; SEXUAL FUNCTION; SEXUAL HEALTH; SEXUAL SATISFACTION; SOCIAL PROBLEM; SPERMATOZOON COUNT; SPERMATOZOON MOTILITY; SPERMIOGRAM; TREATMENT RESPONSE;

ACETYLCARNITINE; ADULT; ARGININE; ASTHENOZOOSPERMIA; CARNITINE; DOUBLE-BLIND METHOD; HUMANS; MALE; MIDDLE AGED; PANAX; PHYTOTHERAPY; SEMEN ANALYSIS; SEXUALITY; SPERM MOTILITY; VITAMIN B COMPLEX;

EID: 78751698486     PISSN: 03932249     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

1. Piomboni P, Gambera L, Serafini F, Campanella G, Morgante G et al. Sperm quality improvement after natural anti-oxidant treatment of asthenoteratospermic men with leukocytospermia. Asian J Androl 2008; 10:201-6
2. Marchini M, Losa G, Falcone L, Piffaretti-Yanez A, Zeeb M et al. Etiology of severe asthenospermia and fertility prognosis. A screening of 5216 semen analyses. Andrologia 1991;23:115-20.
3. Siliprandi N, Sartorelli L, Ciman M, Di Lisa F. Carnitine: metabolism and clinical chemistry. Clin Chim Acta 1989;183:3-11.
4. Spartiol M Brooks H, Zimmermann A, Solioz M, Stieger B et al. Development and characterization of an animal model of carnitine deficiency. Eur J Biochem 2001;268: 1876-87.
5. Moncada ML, Vicari E, Cimino C, Calogero AE, Mongioi A et al. Effect of acetylcarnitine treatment in oligoasthenospermic patients. Acta Eur Fertil 1992;23:221-4.
6. Ji YC, Kim YB, Park SW, Hwang SN, Min BK et al. Neuroprotective effect of ginseng total saponins in experimental traumatic brain injury. J Korean Med Sci 2005;291-6.
7. Tae-Hwan K, Seung Hyun J, Eun-Joo H, Kee-Yoeup P, Jong Kwan P et al. Effects of tissue-cultured mounta in ginseng (Panac ginseng CA Meyer) extract on male patients with erectile dysfunction. Asian J Androl 11: 356; advanced online publication, Feb 23, 2009
8. Zhang H, Zhou QM, Li XD, Xie Y, Duan X, Min FL et al. Ginsenoside R(e) increases fertile and asthenozoospermic infertile human sperm motility by induction of nitric oxide synthase. Arch Pharm Res 2006;29:145-5.
9. Park WS, Shin DY, Kim do R, Yang WM, Chang MS et al. Korean ginseng induces spermatogenesis in rats through the activation of cAMP-responsive element modulator (CREM). Fertil Steril 2007;88:1000-2.
10. WW Hudson . The Walmyr assessment scale scoring manual. WALMYR Publishing Co, Temple1992.
11. WHO laboratory manual for the examination of human semen and sperm-cervical mucus interaction. New York: World Health Organization; 1999.
12. Cavallini G, Caracciolo S, Vitali G, Modenini F, Biagiotti G. Carnitine versus androgen administration in the treatment of sexual dysfunction, depressed mood, and fatigue associated with male aging. Urology 2004;63:641-6. (Pubitemid 38479399)
13. Garolla A, Maiorino M, Roverato A, Roveri A, Ursini F et al. Oral carnitine supplementation increases sperm motility in asthenozoospermic men with normal sperm phospholipid hydroperoxide gluthatione peroxidase levels. Fertil Steril 2005;83:355-61.
14. Lenzi A, Lombardo F, Sgro P, Slacone P, Caponecchia L et al. Use of carnitine therapy in selected cases of male factor infertility a double blind crossover trial. Fertil Steril 2003;79:292-300.
15. Tanphaichitr N. In vitro stimulation of human sperm motility by acetylcarnitine. Int J Fertil 1977; 22:85-91.
16. Zopfgen A, Priem F, Sudhoff F, Jung K, Lenk S et al. Relationship between semen quality and the seminal plasma components carnitine, alpha-glucosidase, fructose, citrate and granulocyte elastase in infertile men compared with a normal population. Hum Reprod 2000;15:840-5.
17. Sigman M, Glass S, Campagnone J, Pryor JL. Carnitine for the treatment of idhiopathic asthenospermia: a randomized, double-blind, placebo-controlled trial. Fertil Steril 2006;85:1409-14.
18. O'Flaherty C, Rodriguez P, Srivastava S. L-arginine promotes capacitation and acrosome reaction in cryopreserved bovine spermatozoa. Biochim Biophys Acta 2004; 1674:215-21. (Pubitemid 40125393)