Effects of norepinephrine on renal perfusion, filtration and oxygenation in vasodilatory shock and acute kidney injury

Intensive Care Medicine

Volumn 37, Issue 1, 2011, Pages 60-67

  Redfors, Bengt ^a   Bragadottir, Gudrun ^a   Sellgren, Johan ^a   Swärd, Kristina ^a   Ricksten, Sven Erik ^a  

^a SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Acute kidney failure; Glomerular filtration rate; Norepinephrine; Oxygen consumption; Renal circulation; Shock

Indexed keywords

EDETIC ACID; NORADRENALIN;

ACUTE KIDNEY FAILURE; AGED; ARTICLE; FEMALE; GLOMERULUS FILTRATION; GLOMERULUS FILTRATION RATE; HEART INDEX; HEART SURGERY; HEMODYNAMICS; HUMAN; KIDNEY BLOOD FLOW; KIDNEY PERFUSION; KIDNEY VEIN; MAJOR CLINICAL STUDY; MALE; MEAN ARTERIAL PRESSURE; MICTURITION; OXYGEN DELIVERY DEVICE; OXYGENATION; SHOCK; THERMODILUTION; VASODILATATION;

ACUTE KIDNEY INJURY; AGED; FEMALE; GLOMERULAR FILTRATION RATE; HUMANS; MALE; NOREPINEPHRINE; OXYGEN; POSTOPERATIVE COMPLICATIONS; RENAL CIRCULATION; SHOCK; VASODILATION;

EID: 78751645681     PISSN: 03424642     EISSN: 14321238     Source Type: Journal    
DOI: 10.1007/s00134-010-2057-4     Document Type: Article

References (40)

1. DW Landry JA Oliver 2001 The pathogenesis of vasodilatory shock N Engl J Med 345 588 595 1:CAS:528:DC%2BD3MXmsl2gtLw%3D 10.1056/NEJMra002709 11529214 (Pubitemid 32772102)
2. AS Kristof S Magder 1999 Low systemic vascular resistance state in patients undergoing cardiopulmonary bypass Crit Care Med 27 1121 1127 1:STN:280:DyaK1Mzitlentw%3D%3D 10.1097/00003246-199906000-00033 10397216 (Pubitemid 29314322)
3. CL Holmes KR Walley 2009 Vasoactive drugs for vasodilatory shock in ICU Curr Opin Crit Care 15 398 402 10.1097/MCC.0b013e32832e96ef 10.1097/MCC. 0b013e32832e96ef 19542884
4. RP Dellinger MM Levy JM Carlet J Bion MM Parker R Jaeschke K Reinhart DC Angus C Brun-Buisson R Beale T Calandra JF Dhainaut H Gerlach M Harvey JJ Marini J Marshall M Ranieri G Ramsay J Sevransky BT Thompson S Townsend JS Vender JL Zimmerman JL Vincent 2008 Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock: 2008 Intensive Care Med 34 17 60 10.1007/s00134-007-0934-2 18058085
5. MH Rosner D Portilla MD Okusa 2008 Cardiac surgery as a cause of acute kidney injury: pathogenesis and potential therapies J Intensive Care Med 23 3 18 10.1177/0885066607309998 10.1177/0885066607309998 18230632
6. MH Rosner MD Okusa 2006 Acute kidney injury associated with cardiac surgery Clin J Am Soc Nephrol 1 19 32 10.2215/CJN.00240605 10.2215/CJN.00240605 17699187
7. RW Schrier PE Arnold JA Gordon TJ Burke 1984 Protection of mitochondrial function by mannitol in ischemic acute renal failure Am J Physiol 247 F365 F369 1:CAS:528:DyaL2cXlsVersbg%3D 6431829
8. K Hoogenberg AJ Smit AR Girbes 1998 Effects of low-dose dopamine on renal and systemic hemodynamics during incremental norepinephrine infusion in healthy volunteers Crit Care Med 26 260 265 1:STN:280:DyaK1c7islKrsg%3D%3D 10.1097/00003246-199802000-00022 9468162 (Pubitemid 28082686)
9. M Richer S Robert M Lebel 1996 Renal hemodynamics during norepinephrine and low-dose dopamine infusions in man Crit Care Med 24 1150 1156 1:STN:280:DyaK283osFChtA%3D%3D 10.1097/00003246-199607000-00014 8674327 (Pubitemid 26249365)
10. R Bellomo JA Kellum SR Wisniewski MR Pinsky 1999 Effects of norepinephrine on the renal vasculature in normal and endotoxemic dogs Am J Respir Crit Care Med 159 1186 1192 1:STN:280:DyaK1M3htVelsw%3D%3D 10194164
11. ZY Peng LA Critchley BS Fok 2005 The effects of increasing doses of noradrenaline on systemic and renal circulations in acute bacteraemic dogs Intensive Care Med 31 1558 1563 10.1007/s00134-005-2741-y 10.1007/s00134-005- 2741-y 16088408 (Pubitemid 41598668)
12. M Joannidis W Druml LG Forni AB Groeneveld P Honore HM Oudemans-van Straaten C Ronco MR Schetz AJ Woittiez Critical Care Nephrology Working Group of the European Society of Intensive Care Medicine 2010 Prevention of acute kidney injury and protection of renal function in the intensive care unit. Expert opinion of the Working Group for Nephrology, ESICM Intensive Care Med 36 392 411 10.1007/s00134-009-1678-y 10.1007/s00134-009-1678-y 19921152
13. EM Redl-Wenzl C Armbruster G Edelmann E Fischl M Kolacny A Wechsler-Fördös P Sporn 1993 The effects of norepinephrine on hemodynamics and renal function in severe septic shock states Intensive Care Med 19 151 154 1:STN:280:DyaK3szgtFaluw%3D%3D 10.1007/BF01720530 8315122
14. P Desjars M Pinaud D Bugnon F Tasseau 1989 Norepinephrine therapy has no deleterious renal effects in human septic shock Crit Care Med 17 426 429 1:STN:280:DyaL1M3gvF2iuw%3D%3D 10.1097/00003246-198905000-00010 2520533
15. JF Cesare JR Ligas ER Hirvela 1993 Enhancement of urine output and glomerular filtration in acutely oliguric patients using low-dose norepinephrine Circ Shock 39 207 210 1:STN:280:DyaK3s3gtFOhsQ%3D%3D 8453745
16. A Bourgoin M Leone A Delmas F Garnier J Albanèse C Martin 2005 Increasing mean arterial pressure in patients with septic shock: effects on oxygen variables and renal function Crit Care Med 33 780 786 1:CAS:528:DC%2BD2MXjtVOjs78%3D 10.1097/01.CCM.0000157788.20591.23 15818105
17. G Bragadottir B Redfors A Nygren J Sellgren SE Ricksten 2009 Low-dose vasopressin increases glomerular filtration rate, but impairs renal oxygenation in post-cardiac surgery patients Acta Anaesthesiol Scand 53 1052 1059 10.1111/j.1399-6576.2009.02037.x 1:STN:280:DC%2BD1MrmslKnuw%3D%3D 10.1111/j.1399-6576.2009.02037.x 19572935
18. B Redfors K Sward J Sellgren SE Ricksten 2009 Effects of mannitol alone and mannitol plus furosemide on renal oxygen consumption, blood flow and glomerular filtration after cardiac surgery Intensive Care Med 35 115 122 10.1007/s00134-008-1206-5 1:CAS:528:DC%2BD1MXotVCkuw%3D%3D 10.1007/s00134-008- 1206-5 18612627
19. B Redfors G Bragadottir J Sellgren K Swärd SE Ricksten 2010 Dopamine increases renal oxygenation: a clinical study in post-cardiac surgery patients Acta Anaesthesiol Scand 54 183 190 10.1111/j.1399-6576.2009.02121.x 1:CAS:528:DC%2BC3cXhvFWqsbs%3D 10.1111/j.1399-6576.2009.02121.x 19764906
20. RL Mehta JA Kellum SV Shah BA Molitoris C Ronco DG Warnock A Levin Acute Kidney Injury Network 2007 Acute kidney injury network: report of an initiative to improve outcomes in acute kidney injury Crit Care 11 R31 10.1186/cc5713 10.1186/cc5713 17331245 (Pubitemid 46604959)
21. R Ceriani M Mazzoni F Bortone S Gandini C Solinas G Susini O Parodi 2003 Application of the sequential organ failure assessment score to cardiac surgical patients Chest 123 1229 1239 10.1378/chest.123.4.1229 12684316 (Pubitemid 36444383)
22. M Kristiansson F Holmquist U Nyman 2009 Ultralow contrast medium doses at CT to diagnose pulmonary embolism in patients with moderate to severe renal impairment: a feasibility study Eur Radiol 20 1321 1330 10.1007/s00330-009-1691- 0 10.1007/s00330-009-1691-0 20033693
23. B Tidgren U Brodin 1988 Plasma renin activity and oxygen content along the renal veins in hypertensive patients Clin Physiol 8 407 416 1:STN:280:DyaL1czhtFOltw%3D%3D 10.1111/j.1475-097X.1988.tb00284.x 3044676
24. K Sward F Valsson J Sellgren SE Ricksten 2004 Bedside estimation of absolute renal blood flow and glomerular filtration rate in the intensive care unit. A validation of two independent methods Intensive Care Med 30 1776 1782 10.1007/s00134-004-2380-8 15375650 (Pubitemid 39297182)
25. LG Andersson LE Bratteby R Ekroth O Wesslén S Hallhagen 1994 Calculation of renal extraction during high diuresis and low renal plasma flow conditions Clin Physiol 14 79 85 1:STN:280:DyaK2c7pvF2gug%3D%3D 10.1111/j.1475-097X.1994.tb00492.x 8149713
26. LJ Hellebrekers JF Liard AL Laborde AS Greene AW Cowley Jr 1990 Regional autoregulatory responses during infusion of vasoconstrictor agents in conscious dogs Am J Physiol 259 H1270 H1277 1:CAS:528:DyaK3cXmt1GisLk%3D 2221130
27. R Loutzenhiser K Griffin G Williamson A Bidani 2006 Renal autoregulation: new perspectives regarding the protective and regulatory roles of the underlying mechanisms Am J Physiol Regul Integr Comp Physiol 290 R1153 R1167 10.1152/ajpregu.00402.2005 1:CAS:528:DC%2BD28XkvFSmtLo%3D 16603656
28. WA Cupples B Braam 2007 Assessment of renal autoregulation Am J Physiol Renal Physiol 292 F1105 F1123 10.1152/ajprenal.00194.2006 1:CAS:528: DC%2BD2sXks1Kitbs%3D 10.1152/ajprenal.00194.2006 17229679 (Pubitemid 46572430)
29. PB Persson H Ehmke B Nafz HR Kirchheim 1990 Resetting of renal autoregulation in conscious dogs: angiotensin II and alpha1-adrenoceptors Pflugers Arch 417 42 47 1:CAS:528:DyaK3MXnsFGntg%3D%3D 10.1007/BF00370767 1981392 (Pubitemid 20330117)
30. MW Dünser J Takala H Ulmer VD Mayr G Luckner S Jochberger F Daudel P Lepper WR Hasibeder SM Jakob 2009 Arterial blood pressure during early sepsis and outcome Intensive Care Med 35 1225 1233 10.1007/s00134-009-1427-2 10.1007/s00134-009-1427-2 19189077
31. M Schetz 2002 Vasopressors and the kidney Blood Purif 20 243 251 1:CAS:528:DC%2BD38XhsFSjurY%3D 10.1159/000047016 11867871 (Pubitemid 34195667)
32. GL Bakris JH Stein 1993 Diabetic nephropathy Dis Mon 39 573 611 1:STN:280:DyaK3szislKltA%3D%3D 8334915
33. PK Carmines 2010 The renal vascular response to diabetes Curr Opin Nephrol Hypertens 19 85 90 10.1097/MNH.0b013e32833240fc 1:CAS:528: DC%2BD1MXhsFentr%2FO 10.1097/MNH.0b013e32833240fc 19770755
34. C Beretta-Piccoli P Weidmann 1981 Exaggerated pressor responsiveness to norepinephrine in nonazotemic diabetes mellitus Am J Med 71 829 835 1:STN:280:DyaL38%2FmsFGksw%3D%3D 10.1016/0002-9343(81)90375-2 7304655
35. WR Jacobs YL Chan 1987 Effect of norepinephrine on renal tubular Na-K-ATPase and oxygen consumption Life Sci 40 1571 1578 1:CAS:528: DyaL2sXhvV2lsLo%3D 10.1016/0024-3205(87)90122-6 3031404 (Pubitemid 17046053)
36. CA Block HL Manning 2002 Prevention of acute renal failure in the critically ill Am J Respir Crit Care Med 165 320 324 11818313
37. M Brezis Y Agmon FH Epstein 1994 Determinants of intrarenal oxygenation. I. Effects of diuretics Am J Physiol 267 F1059 F1062 1:CAS:528: DyaK2MXivFGktLc%3D 7810692
38. H Schachinger M Klarhöfer L Linder J Drewe K Scheffler 2006 Angiotensin II decreases the renal MRI blood oxygenation level-dependent signal Hypertension 47 1062 1066 10.1161/01.HYP.0000220109.98142.a3 1:CAS:528:DC%2BD28XksVOmurc%3D 10.1161/01.HYP.0000220109.98142.a3 16618841 (Pubitemid 44289162)
39. D LeDoux ME Astiz CM Carpati EC Rackow 2000 Effects of perfusion pressure on tissue perfusion in septic shock Crit Care Med 28 2729 2732 1:STN:280:DC%2BD3cvntFKnug%3D%3D 10.1097/00003246-200008000-00007 10966242
40. A Nygren A Thoren SE Ricksten 2007 Norepinephrine and intestinal mucosal perfusion in vasodilatory shock after cardiac surgery Shock 28 536 543 1:CAS:528:DC%2BD2sXhtlSqurjL 17607155