A novel approach for the purification and proteomic analysis of pathogenic immunoglobulin free light chains from serum

Biochimica et Biophysica Acta - Proteins and Proteomics

Volumn 1814, Issue 3, 2011, Pages 409-419

  Lavatelli, Francesca ^a   Brambilla, Francesca ^b   Valentini, Veronica ^a   Rognoni, Paola ^a   Casarini, Simona ^a   Di Silvestre, Dario ^b   Perfetti, Vittorio ^c   Palladini, Giovanni ^a   Sarais, Gabriele ^c   Mauri, Pierluigi ^b   Merlini, Giampaolo ^a,c  

^a UNIVERSITY OF PAVIA   (Italy)

^b INSTITUTE OF BIOMEDICAL TECHNOLOGIES   (Italy)

^c FONDAZIONE IRCCS POLICLINICO SAN MATTEO   (Italy)

Author keywords

Amyloidosis; Immunoglobulin free light chains; Immunoprecipitation; Post translational modifications; Proteomics

Indexed keywords

AGAROSE; IMMUNOGLOBULIN KAPPA CHAIN; IMMUNOGLOBULIN LAMBDA CHAIN; TRYPTOPHAN;

ADULT; AGED; AMINO ACID SEQUENCE; AMYLOIDOSIS; ARTICLE; BONE MARROW; CHEMICAL MODIFICATION; CLINICAL ARTICLE; COVALENT BOND; CYSTEINYLATION; DIMERIZATION; FEMALE; HUMAN; IMMUNOBLOTTING; IMMUNOFIXATION; IMMUNOGLOBULIN BLOOD LEVEL; IMMUNOLOGICAL PROCEDURES; IMMUNONEPHELOMETRY; IMMUNOPRECIPITATION; IMMUNOPURIFICATION; MALE; MASS SPECTROMETRY; MONOCLONAL IMMUNOGLOBULINEMIA; MYELOMA; OXIDATION; PATHOGENICITY; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN PROCESSING; PROTEIN PURIFICATION; PROTEOMICS; QUANTITATIVE ANALYSIS; TWO DIMENSIONAL GEL ELECTROPHORESIS;

ADULT; AGED; AMINO ACID SEQUENCE; AMYLOIDOSIS; ANTIBODIES, MONOCLONAL; CHROMATOGRAPHY, LIQUID; FEMALE; HUMANS; IMMUNOGLOBULIN KAPPA-CHAINS; IMMUNOGLOBULIN LAMBDA-CHAINS; IMMUNOGLOBULIN LIGHT CHAINS; IMMUNOPRECIPITATION; MALE; MASS SPECTROMETRY; MIDDLE AGED; MOLECULAR SEQUENCE DATA; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEOMICS; SEQUENCE ALIGNMENT;

EID: 78751642693     PISSN: 15709639     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbapap.2010.12.012     Document Type: Article

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