Rapakinin, Arg-Ile-Tyr, derived from rapeseed napin, shows anti-opioid activity via the prostaglandin IP receptor followed by the cholecystokinin CCK2 receptor in mice

Peptides

Volumn 32, Issue 2, 2011, Pages 281-285

  Yamada, Yuko ^a   Ohinata, Kousaku ^a   Lipkowski, Andrzej W ^b   Yoshikawa, Masaaki ^c  

^a KYOTO UNIVERSITY   (Japan)

^b MOSSAKOWSKI MEDICAL RESEARCH CENTRE   (Poland)

^c OSAKA UNIVERSITY   (Japan)

Author keywords

Anti opioid activity; CCK2 receptor; Cholecystokinin; IP receptor; Prostaglandin I2; Rapakinin

Indexed keywords

CAY 10441; CHOLECYSTOKININ A RECEPTOR; CHOLECYSTOKININ B RECEPTOR; CHOLECYSTOKININ B RECEPTOR ANTAGONIST; CHOLECYSTOKININ OCTAPEPTIDE; CIPROSTENE; LORGLUMIDE; LY 225910; MORPHINE; NAPIN; OPIATE; PROSTAGLANDIN RECEPTOR; PROSTAGLANDIN RECEPTOR BLOCKING AGENT; RAPAKININ; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTINOCICEPTION; ARTICLE; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DRUG EFFECT; DRUG RECEPTOR BINDING; EXPERIMENTAL TEST; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RAPESEED; TAIL PINCH TEST;

2S ALBUMINS, PLANT; ANIMALS; AREA UNDER CURVE; BRASSICA RAPA; EPOPROSTENOL; INJECTIONS, INTRAVENTRICULAR; MALE; MICE; MICE, INBRED STRAINS; MORPHINE; NARCOTIC ANTAGONISTS; OLIGOPEPTIDES; PAIN MEASUREMENT; QUINAZOLINONES; REACTION TIME; RECEPTOR, CHOLECYSTOKININ B; RECEPTORS, PROSTAGLANDIN; SIGNAL TRANSDUCTION; SINCALIDE;

BRASSICA NAPUS; MUS;

EID: 78751642535     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.peptides.2010.11.015     Document Type: Article

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