Corticosteroids affect nitric oxide generation, total free radicals production, and nitric oxide synthase activity in monocytes of asthmatic patients

Molecular and Cellular Biochemistry

Volumn 346, Issue 1-2, 2011, Pages 31-37

  Khanduja, Krishan Lal ^a   Kaushik, Gaurav ^a   Khanduja, Suchit ^a   Pathak, Chander Mohan ^a   Laldinpuii, Judy ^a   Behera, Degambar ^a  

^a POSTGRADUATE INSTITUTE OF MEDICAL EDUCATION AND RESEARCH   (India)

Author keywords

Asthma; Blood monocytes; Corticosteroids; Inducible nitric oxide synthase; Nitric oxide; Total free radical activity

Indexed keywords

CORTICOSTEROID; FREE RADICAL; INDUCIBLE NITRIC OXIDE SYNTHASE; MESSENGER RNA; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; REACTIVE OXYGEN METABOLITE; STEROID;

ADULT; ARTICLE; ASTHMA; BLOOD; CELL ACTIVATION; CONTROLLED STUDY; CORTICOSTEROID THERAPY; DIAGNOSTIC VALUE; DISEASE SEVERITY; DRUG EFFICACY; ENZYME ACTIVITY; FEMALE; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; MALE; MONOCYTE; PROTEIN INDUCTION; RECEPTOR UPREGULATION; TRANSCRIPTION REGULATION; TREATMENT DURATION;

ADRENAL CORTEX HORMONES; ASTHMA; CASE-CONTROL STUDIES; FREE RADICALS; HUMANS; MONOCYTES; NITRIC OXIDE; NITRIC OXIDE SYNTHASE;

EID: 78751636356     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-010-0588-1     Document Type: Article

References (35)

1. DI Bernstein 2008 ABCs of asthma Clin Cornerstone 8 9 25 10.1016/S1098-3597(08)80010-5 18713655
2. P Fireman 2003 Understanding asthma pathophysiology Allergy Asthma Proc 24 79 83 1:CAS:528:DC%2BD3sXkt1Kmtrs%3D 12776439
3. MS Dunnil GR Massarella JA Anderson 1969 A quantitative anatomy of the bronchi in normal subjects, in status asthmatics, in chronic bronchitis and in emphysema Thorax 24 176 179 10.1136/thx.24.2.176
4. GD Raphael CD Metcalfe 1986 Mediators of airway inflammation Eur J Respir Dis 60 44 56
5. AA Andreadis SL Hazen SA Comhair SC Erzurum 2003 Oxidative and nitrosative events in asthma Free Radic Biol Med 35 213 225 1:CAS:528: DC%2BD3sXls1Omsbs%3D 10.1016/S0891-5849(03)00278-8 12885584 (Pubitemid 37288922)
6. PA Henricks FP Nijkamp 2001 Reactive oxygen species as mediators in asthma Pulm Pharmacol Ther 14 409 420 1:CAS:528:DC%2BD38Xit1yltg%3D%3D 10.1006/pupt.2001.0319 11782121 (Pubitemid 34081693)
7. RMJ Palmer AG Ferridge S Moncada 1987 Nitric oxide release accounts for the biological activity of endothelium derived relaxing factor Nature 327 524 526 1:CAS:528:DyaL2sXktlCjs70%3D 10.1038/327524a0 3495737 (Pubitemid 17085822)
8. Q Hamid DR Springall V Riveros-Moreno P Chanez P Howarth A Redington J Bousquet P Godard S Holgate JM Polak 1993 Induction of NOS in asthma Lancet 342 1510 1513 1:STN:280:DyaK2c%2Fns12huw%3D%3D 10.1016/S0140-6736(05)80083-2 7504773 (Pubitemid 23362167)
9. M Cluzel M Damon P Chanez J Bousquet A Crastes de Paulet FB Michel P Godard 1987 Enhanced alveolar cell luminol dependent chemiluminescence in asthma J Allergy Clin Immunol 80 195 201 1:STN:280:DyaL2s3otFahsg%3D%3D 10.1016/0091-6749(87)90129-1 3611540
10. I Vachier H Damon C Le-Doucon P De paulet Chanez FB Michel P Godard 1992 Increased oxygen species generation in blood monocytes of asthmatic patients Am Rev Respir Dis 146 1161 1166 1:STN:280:DyaK3s%2Fntlahsw%3D%3D 1443865
11. P Chanez G Dent T Yukawa PJ Barnes KF Chung 1990 Generation of oxygen free radicals from blood eosinophiles from asthma patients after stimulation with PAF or Phorbol ester Eur Respir J 3 1002 1007 1:STN:280: DyaK3M7ks1Kktg%3D%3D 2289546
12. MN Jarjour WJ Calhoun 1994 Enhanced production on oxygen radicals in asthma J Lab Clin Med 123 131 136 1:STN:280:DyaK2c7hsl2hsA%3D%3D 8288953
13. R Newton 2000 Occasional review. Molecular mechanisms of glucocorticoid action: what is important? Thorax 55 603 613 1:STN:280:DC%2BD3czhs1ahtw%3D%3D 10.1136/thorax.55.7.603 10856322 (Pubitemid 30398277)
14. Y Tanizaki M Hosokawa Y Goda K Akagi H Takeyama I Kimura 1982 Numerical changes in blood monocytes in bronchial asthma Acta Med Okayama 36 341 348 1:STN:280:DyaL3s%2Fps1Kguw%3D%3D 7180570
15. G Ibeth I Joanna K Aldona Dembiska P Joanna W Alicja A Polus G Iwona B Stanisław M Małgorzata S Andrzej 1998 Determination of nitrite/nitrate in human biological material by the simple Griess reaction Clin Chim Acta 274 177 188 10.1016/S0009-8981(98)00060-6 (Pubitemid 28269300)
16. DS Berdt SH Snyder 1990 Isolation of NOS, acalmodulin requiring enzyme Proc Natl Acad Sci 87 682 685 10.1073/pnas.87.2.682
17. P Chomczynski N Sacchi 1987 Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction Anal Biochem 162 156 159 1:CAS:528:DyaL2sXitFSns7Y%3D 10.1016/0003-2697(87)90021-2 2440339
18. RC Allen LD Loose 1976 Phagocytic activation of luminol dependent chemiluminescence in rabbit alveolar and peritoneal macrophages Biochem Biophys Res Commun 69 245 252 1:CAS:528:DyaE28XhslyisLc%3D 10.1016/S0006-291X(76)80299-9 1259763
19. MM Bradford 1976 A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding Anal Biochem 72 248 254 1:CAS:528:DyaE28XksVehtrY%3D 10.1016/0003-2697(76)90527- 3 942051
20. DH Yates SA Kharitnov RA Robbins PS Thomas PJ Barnes 1995 Effects of a NOS inhibitor and a glucocorticoid on exhaled NO Am J Respir Crit Care Med 152 892 896 1:STN:280:DyaK2Mzpt1yltQ%3D%3D 7663801
21. RP Bowler JD Crapo 2002 Oxidative stress in allergic respiratory diseases J Allergy Clin Immunol 110 349 356 1:CAS:528:DC%2BD38XnvVSrur4%3D 10.1067/mai.2002.126780 12209079
22. J Batra TP Singh U Mabalirajan A Sinha R Prasad B Ghosh 2007 Association of inducible nitric oxide synthase with asthma severity, total serum immunoglobulin E and blood eosinophil levels Thorax 62 16 22 10.1136/thx.2006.057935 17189532 (Pubitemid 46101761)
23. RB Lorsbach WJ Murphy CJ Lowenstein SH Snyder 1993 Expression of NOS gene in mouse macrophages activated for tumor cell killing: molecular basis for the synergy between interferon gamma and lipopolysaccharide J Biol Chem 268 1908 1913 1:CAS:528:DyaK3sXht1aqt7k%3D 7678412
24. Y Vodovotz C Bogdan J Paik QW Xie C Nathan 1993 Mechanism of suppression of macrophges. NO release by TGF beta J Exp Med 178 605 613 1:CAS:528: DyaK3sXlsFyjsb0%3D 10.1084/jem.178.2.605 7688028
25. MW Radowski RMJ Palmer S Mocada 1990 Glucocorticoids inhibit the expression of an inducible but not constitutive NOS in vascular epithelial cell Proc Natl Acad Sci 87 10043 11049 10.1073/pnas.87.24.10043
26. JL Puckett SC George 2008 Partitioned exhaled nitric oxide to non-invasively assess asthma Respir Physiol Neurobiol 163 166 177 1:CAS:528:DC%2BD1cXht12rtr7J 10.1016/j.resp.2008.07.020 18718562
27. S Meltzer B Goldberg P Lad J Easton 1989 Superoxide generation and its modulation by adenosine in the neutrophiles of subjects with asthma J Allergy Clin Immunol 83 960 966 1:STN:280:DyaL1M3jsV2kuw%3D%3D 10.1016/0091-6749(89) 90112-7 2541190 (Pubitemid 19147190)
28. JB Sedgwick KM Kager WW Busse 1990 Superoxide generation by hypodense eosinophils from patients with asthma Am Rev Respir Dis 142 120 125 1:STN:280:DyaK3czhsVSksA%3D%3D 2164333
29. WJ Calhoun RK Bush 1990 Enhanced ROS metabolism of airspace cells and airway inflammation follow antigen challenge in human asthma J Allergy Clin Immunol 86 306 313 1:STN:280:DyaK3M%2FhtVeltw%3D%3D 10.1016/S0091-6749(05)80092- 2 2212406
30. RJ Flower NJ Rothwill 1994 Lipocortin. Cellular mechanism and clinical relevance Trends Pharmacol Sci 5 71 76 10.1016/0165-6147(94)90281-X (Pubitemid 24086941)
31. Y Bromberg E Pich 1994 Unsaturated fatty acids as second messengers of superoxide generation by macrophages Trends Pharmacol Sci 15 71 76 10.1016/0165-6147(94)90281-X (Pubitemid 24086941)
32. RM Schutz SKW Manda MG Altom 1995 Effect of various inhibitors of arachidonic acid oxygenation in macrophage superoxide release and tumoricidal activity J Immunol 135 2040 2044
33. M Majori I Vachier P Godard M Farce J Bousquet P Chanez 1998 Superoxide anion production by monocytes of corticosteroid-treated asthmatic patients Eur Respir J 11 133 138 1:CAS:528:DyaK1cXhvVyltLY%3D 10.1183/09031936.98.11010133 9543282 (Pubitemid 28081807)
34. JS Rana MA Mittleman J Sheikh FB Hu JE Manson GA Colditz FE Speizer RG Barr CA Camargo 2004 Chronic obstructive pulmonary disease, asthma, and risk of type 2 diabetes in women Diabetes Care 27 2478 2484 10.2337/diacare.27.10.2478 15451919 (Pubitemid 39281404)
35. JL Faul SR Wilson JW Chu J Canfield WG Kuschner 2009 The effect of an inhaled corticosteroid on glucose control in type 2 diabetes Clin Med Res 7 14 20 1:CAS:528:DC%2BD1MXhtVOmsbjP 10.3121/cmr.2009.824 19251584