Health impact assessment of a reduction in ambient PM2.5 levels in Spain

Environment International

Volumn 37, Issue 2, 2011, Pages 342-348

  Boldo, Elena ^a,b   Linares, Cristina ^a,b   Lumbreras, Julio ^c   Borge, Rafael ^c   Narros, Adolfo ^c   García Pérez, Javier ^a,b   Fernández Navarro, Pablo ^a,b   Pérez Gómez, Beatriz ^a,b   Aragonés, Nuria ^a,b   Ramis, Rebeca ^a,b   Pollán, Marina ^a,b   Moreno, Teresa ^d   Karanasiou, Angeliki ^d   López Abente, Gonzalo ^a,b  

^a CARLOS III INSTITUTE OF HEALTH   (Spain)

^b CIBER EPIDEMIOLOGÍA Y SALUD PÚBLICA CIBERESP   (Spain)

^c UNIVERSIDAD POLITÉCNICA DE MADRID   (Spain)

^d INSTITUTE OF ENVIRONMENTAL ASSESSMENT AND WATER RESEARCH   (Spain)

Author keywords

Environmental pollution; Mortality; Particulate matter; Risk benefit assessment; Software tool

Indexed keywords

AIR POLLUTION; AIR QUALITY; COMPUTER AIDED SOFTWARE ENGINEERING; ENVIRONMENTAL PROTECTION AGENCY; HEALTH; PARTICLES (PARTICULATE MATTER); POLLUTION CONTROL; RISK ASSESSMENT;

COMMUNITY MULTI-SCALE AIR QUALITY MODELS; ENVIRONMENTAL POLLUTIONS; HEALTH IMPACT ASSESSMENT; MORTALITY; NATIONAL EMISSIONS INVENTORIES; PARTICULATE MATTER; RISK BENEFITS; US ENVIRONMENTAL PROTECTION AGENCY;

POLLUTION;

AIR QUALITY; ATMOSPHERIC POLLUTION; BASELINE CONDITIONS; COMPUTER SIMULATION; HEALTH IMPACT; HEALTH RISK; MORTALITY RISK; NUMERICAL MODEL; POLLUTION CONTROL; POLLUTION INCIDENCE; POLLUTION POLICY; RISK ASSESSMENT; SOFTWARE; SUSPENDED PARTICULATE MATTER;

ADULT; AGED; AIR POLLUTANT; AIR POLLUTION; AIR QUALITY CONTROL; AIR QUALITY STANDARD; ARTICLE; CAUSE OF DEATH; COMPUTER PROGRAM; CONTROLLED STUDY; ENVIRONMENTAL EXPOSURE; GOVERNMENT; HEALTH CARE POLICY; HEALTH HAZARD; HUMAN; LONG TERM EXPOSURE; LUNG CANCER; MORTALITY; PARTICULATE MATTER; POLLUTION CONTROL; PRIORITY JOURNAL; RISK ASSESSMENT; SPAIN;

BALEARIC ISLANDS; IBERIAN PENINSULA; MEDITERRANEAN SEA; SPAIN;

EID: 78751632874     PISSN: 01604120     EISSN: 18736750     Source Type: Journal    
DOI: 10.1016/j.envint.2010.10.004     Document Type: Article

References (43)

1. AAI (Abt Associates Inc) Environmental Benefits Mapping and Analysis Program (BenMAP Version 4.0.27). Bethesda, MD. Prepared for Environmental Protection Agency, Office of Air Quality Planning and Standards, Innovative Strategies and Economics Group. Research Triangle Park, NC. 2005 Available:, Accessed 13 March 2010. http://www.abtassociates.com/.
2. AAI (Abt Associates Inc) BenMap. User's manual. Prepared for Office of Air Quality Planning and Standards, US EPA. 2008a Available:, Accessed 20 September 2010. http://www.epa.gov/oaqps001/benmap/models/BenMapManualSept08.pdf.
3. AAI (Abt Associates Inc) BenMap. User's manual. Appendices. Prepared for Office of Air Quality Planning and Standards, US EPA. 2008b Available:, Accessed 20 September 2010. http://www.epa.gov/oaqps001/benmap/models/BenMAPappendicesSept08.pdf.
4. Alonso E., Martínez T., Cambra K. Evaluación en cinco ciudades españolas del impacto en salud de la contaminación atmosférica por partículas. Proyecto europeo APHEIS. Gac Sanit 2005, 79:297-308.
5. Bae H.J., Park J. Health benefits of improving air quality in the rapidly aging Korean society. Sci Total Environ 2009, 407:5971-5977.
6. Ballester F., Medina S., Boldo E., Goodman P., Neuberger M., Iniguez C., et al. Reducing ambient levels of fine particulates could substantially improve health: a mortality impact assessment for 26 European cities. J Epidemiol Community Health 2008, 62:98-105.
7. Boldo E., Medina S., LeTertre A., Hurley F., Mucke H.G., Ballester F., et al. Apheis: health impact assessment of long-term exposure to PM(2.5) in 23 European cities. Eur J Epidemiol 2006, 21:449-458.
8. Borge R., Lumbreras J., Rodriguez E. Development of a high-resolution emission inventory for Spain using the SMOKE modelling system: a case study for the years 2000 and 2010. Environ Modell Softw 2008, 23:1026-1044.
9. Brunekreef B., Beelen R., Hoek G., Schouten L., Bausch-Goldbohm S., Fischer P., et al. Effects of long-term exposure to traffic-related air pollution on respiratory and cardiovascular mortality in the Netherlands: The NLCS-AIR study. Res Rep Health Eff Inst 2009, 5-71.
10. Byun D., Ching J. Science algorithms of the EPA models-3 community multiscale air quality (CMAQ) modeling system [microform]. 1999, U.S. Environmental Protection Agency, Office of Research and Development, Washington, DC, Available:, Accessed: 10 May 2010. http://www.epa.gov/AMD/CMAQ/000_cover_exec.pdf, D.W. Byun, J.K.S. Ching (Eds.).
11. Byun D., Schere K.L. Review of the governing equations, computational algorithms, and other components of the models-3 community multiscale air quality (CMAQ) modeling system. Appl Mech Rev 2006, 59:51-77.
12. Clancy L., Goodman P., Sinclair H., Dockery D.W. Effect of air-pollution control on death rates in Dublin, Ireland: an intervention study. Lancet 2002, 360:1210-1214.
13. Curtis L., Rea W., Smith-Willis P., Fenyves E., Pan Y. Adverse health effects of outdoor air pollutants. Environ Int 2006, 32(6):815-830. [Aug].
14. Davidson K., Hallberg A., McCubbin D., Hubbell B. Analysis of PM2.5 using the Environmental Benefits Mapping and Analysis Program (BenMAP). J Toxicol Environ Health A 2007, 70:332-346.
15. Diaz J., Alberdi J.C., Pajares M.S., Lopez C., Lopez R., Lage M.B., et al. A model for forecasting emergency hospital admissions: effect of environmental variables. J Environ Health 2001, 64:9-15.
16. Dockery D.W., Pope C.A., Xu X., Spengler J.D., Ware J.H., Fay M.E., et al. An association between air pollution and mortality in six U.S. cities. N Engl J Med 1993, 329:1753-1759.
17. EEA (European Environment Agency) EMEP/CORINAIR emission inventory guidebook 2006, Available:, (EEA Technical Report no. 30). Accessed 20 September 2010. http://www.eea.europa.eu/publications/EMEPCORINAIR3.
18. Fann N., Fulcher C.M., Hubbell B.J. The influence of location, source, and emission type in estimates of the human health benefits of reducing a ton of air pollution. Air Qual Atmos Health 2009, 2:169-176.
19. Hoek G., Fischer P., Van Den B.P., Goldbohm S., Brunekreef B. Estimation of long-term average exposure to outdoor air pollution for a cohort study on mortality. J Expo Anal Environ Epidemiol 2001, 11:459-469.
20. Jimenez E., Linares C., Rodriguez L.F., Bleda M.J., Diaz J. Short-term impact of particulate matter (PM2.5) on daily mortality among the over-75 age group in Madrid (Spain). Sci Total Environ 2009, 407:5486-5492.
21. Krzyzanowski M., Cohen A., Anderson R. Quantification of health effects of exposure to air pollution. Occup Environ Med 2002, 59:791-793.
22. Laden F., Schwartz J., Speizer F.E., Dockery D.W. Reduction in fine particulate air pollution and mortality: extended follow-up of the Harvard Six Cities study. Am J Respir Crit Care Med 2006, 173:667-672.
23. Linares C., Diaz J. Short-term effect of PM(2.5) on daily hospital admissions in Madrid (2003-2005). Int J Environ Health Res 2010, 20:129-140.
24. Lumbreras J., Borge R., de Andres J.M., Rodriguez E. A model to calculate consistent atmospheric emission projections and its application to Spain. Atmos Environ 2008, 42:5251-5266.
25. Martinez F., Simon-Soria F., Lopez-Abente G. Evaluation of the impact of the heat wave in the summer of 2003 on mortality. Gac Sanit 2004, 18(Suppl 1):250-258.
26. Martuzzi M., Krzyzanowski M., Bertollini R. Health impact assessment of air pollution: Providing further evidence for public health action. Eur Respir J Suppl 2003, 40:86s-91s.
27. Medina S., Plasencia A., Ballester F., Mucke H.G., Schwartz J. Apheis: public health impact of PM10 in 19 European cities. J Epidemiol Community Health 2004, 58:831-836.
28. MMA (Ministry of Environment) Spain's National Atmospheric Emission Inventory 2006, Available:, Accessed 28 September 2010. http://www.mma.es/portal/secciones/calidad_contaminacion/atmosfera/emisiones/inventario.htm.
29. Naess O., Piro F.N., Nafstad P., Smith G.D., Leyland A.H. Air pollution, social deprivation, and mortality: a multilevel cohort study. Epidemiology 2007, 18:686-694.
30. National Research Council Estimating the public health benefits of purposed air pollution regulations 2002, National Academic Press, Washington, DC, Available:, Accessed 4 May 2010. http://www.nap.edu/catalog.php?record_id=10511.
31. NEEDS (New Energy Externalities Developments for Sustainability) Deliverable 3.7-RS1b-D3.7 "A set of concentration-response functions". Institute of Occupational Medicine, United Kingdom 2007, Available: http://www.needs-project.org/RS1b/NEEDS_Rs1b_D3.7.pdf. Accessed 20 September 2010.
32. Nieuwenhuijsen M., Paustenbach D., Duarte-Davidson R. New developments in exposure assessment: the impact on the practice of health risk assessment and epidemiological studies. Environ Int 2006, 32(8):996-1009. [Dec].
33. Orozco G, Borge R, Lumbreras J, Rodriguez E. Sensitivity analysis and preliminary results of the air pollution health-impact assessment system for the Iberian Peninsula. 7th International Conference on Air Quality. Special Session on Air Quality and Health. Istanbul (Turkey). Personal communication. 2009.
34. Perez L., Sunyer J., Kunzli N. Estimating the health and economic benefits associated with reducing air pollution in the Barcelona metropolitan area (Spain). Gac Sanit 2009, 23:287-294.
35. Peters A., Dockery D.W., Muller J.E., Mittleman M.A. Increased particulate air pollution and the triggering of myocardial infarction. Circulation 2001, 103:2810-2815.
36. Pope C.A., Dockery D.W. Health effects of fine particulate air pollution: lines that connect. J Air Waste Manage Assoc 2006, 56:709-742.
37. Pope C.A., Burnett R.T., Thun M.J., Calle E.E., Krewski D., Ito K., et al. Lung cancer, cardiopulmonary mortality, and long-term exposure to fine particulate air pollution. JAMA 2002, 287:1132-1141.
38. Rabl A. Analysis mortality in terms of life expectancy changes: relation between time series, intervention and cohort studies. Environmental health: a global access science source 2006, 5:1. Available:, Accessed 21 September 2010. http://www.ehjournal.net/content/5/1/1.
39. SCHER-Scientific Committee on Health Environmental Risks Opinion on "New evidence of air pollution effects on human health and the environment". European Commission, Health and Consumer Protection Directorate, 1-15 2005, Available:, Accessed: 25 May 2010. http://ec.europa.eu/health/ph_risk/committees/04_scher/docs/scher_o_009.pdf.
40. Tagaris E., Liao K.J., Delucia A.J., Deck L., Amar P., Russell A.G. Potential impact of climate change on air pollution-related human health effects. Environ Sci Technol 2009, 43:4979-4988.
41. US EPA Review of the draft analytical plan for EPA's second prospective analysis-benefits and costs of the Clean Air Act 1990-2020: an advisory by the Advisory Council on Clean Air Compliance Analysis. Washington DC: EPA-SAB-COUNCIL-ADV-01-004. 2001 Available:, Accessed: 30 July 2010. http://yosemite.epa.gov/sab/sabproduct.nsf/572DC1989A3986CC8525718D006BAB8B/%24File/councila01004.pdf.
42. WHO Evaluation and use of epidemiological evidence for environmental health risk assessment: WHO guideline document. Environ Health Perspect 2000, 108:997-1002.
43. WHO Health aspects of air pollution with particulate matter, ozone and nitrogen dioxide. Copenhagen: WHO Regional Office for Europe: report from WHO working group meeting Bonn 2003, Available:, Accessed 18 June 2010. http://www.euro.who.int/__data/assets/pdf_file/0005/112199/E79097.pdf.