Biochemical characterization of breast tumors by in vivo and in vitro magnetic resonance spectroscopy (MRS)

Biophysical Reviews

Volumn 1, Issue 1, 2009, Pages 21-26

  Sharma, Uma ^a   Jagannathan, Naranamangalam R ^a  

^a ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

Breast cancer, Choline, Biomarker; Ex vivo; In vitro; In vivo; Magnetic resonance spectroscopy (MRS); Therapeutic response

Indexed keywords

EID: 78751624579     PISSN: 18672450     EISSN: 18672469     Source Type: Journal    
DOI: 10.1007/s12551-008-0004-1     Document Type: Review

References (45)

1. Baek HM, Chen JH, Yu HJ et al (2008) Detection of choline signal in human breast lesions with chemical-shift imaging. J Magn Reson Imaging 27: 1114-1121 doi: 10. 1002/jmri. 21309.
2. 1H MR spectroscopy using water as an internal reference at 1. 5 T. Magn Reson Mater Phy 19: 96-104 doi: 10. 1007/s10334-006-0032-4.
3. Bartella L, Morris EA, Dershaw DD et al (2006) Proton MR spectroscopy with choline peak as malignancy marker improves positive predictive value for breast cancer diagnosis: preliminary study. Radiology 239: 686-692 doi: 10. 1148/radiol. 2393051046.
4. 1H) MR spectroscopy. Radiology 245: 80-87 doi: 10. 1148/radiol. 2451061639.
5. Bathen TF, Jensen LR, Sitter B et al (2007) MR-determined metabolic phenotype of breast cancer in prediction of lymphatic spread, grade, and hormone status. Breast Cancer Res Treat 104: 181-189 doi: 10. 1007/s10549-006-9400-z.
6. 1H-NMR spectroscopy and self-organizing maps. NMR Biomed 16: 1-11 doi: 10. 1002/nbm. 797.
7. 1H MR spectroscopy. Magn Reson Med 50: 1134-1143 doi: 10. 1002/mrm. 10654.
8. 1H MRS at 4 Tesla. Magn Reson Med 52: 1239-1245 doi: 10. 1002/mrm. 20277.
9. 1H MRS at 7 Tesla. Proc Int Soc Magn Reson Med 14: 580.
10. Cecil KM, Schnall MD, Siegelman ES et al (2001) The evaluation of human breast lesions with magnetic resonance imaging and proton magnetic resonance spectroscopy. Breast Cancer Res Treat 68: 45-54 doi: 10. 1023/A: 1017911211090.
11. Cheng LL, Chang IW, Smith BL et al (1998) Evaluating human breast ductal carcinomas with high-resolution magic-angle spinning proton magnetic resonance spectroscopy. J Magn Reson 135: 194-202 doi: 10. 1006/jmre. 1998. 1578.
12. Danishad KA, Seenu V, Jagannathan NR (2007) 2D MRSI in locally advanced breast cancer: Assessment of tumor response in patients undergoing neo-adjuvant chemotherapy. Proc Int Soc Mag Reson Med 15: 557.
13. Do R, Moy L, Salibi N et al (2006) Can MRS improve our ability to distinguish between benign and malignant lesions? Proc Int Soc Magn Reson Med 14: 2876.
14. Gary MT, Cheung HS, Pang L et al (2003) Characterization of lesions of the breast with proton MR spectroscopy: comparison of carcinomas, benign lesions, and phyllodes tumors. AJR 181: 1267-1273.
15. Gary MT, David KY, Ann DK et al (2007) In-vivo magnetic resonance spectroscopy of breast cancer lesions: an update. Breast Cancer Res Treat 104: 249-255 doi: 10. 1007/s10549-006-9412-8.
16. Glunde K, Jie C, Bhujwalla ZM (2004) Molecular causes of the aberrant choline phospholipid metabolism in breast cancer. Cancer Res 64: 4270-4276 doi: 10. 1158/0008-5472. CAN-03-3829.
17. Greenlee RT, Hill-Harmon MB, Murray T et al (2001) Cancer statistics. CA Cancer J Clin 51: 5-36.
18. 1H NMR spectroscopic characterization of perchloric acid extracts from breast carcinomas and non-involved breast tissue. NMR Biomed 7: 181-194 doi: 10. 1002/nbm. 1940070405.
19. Jagannathan NR, Singh M, Govindaraju V et al (1998) Volume localized in vivo proton MR spectroscopy of breast carcinoma: variation of water-fat ratio in patients receiving chemotherapy. NMR Biomed 11: 414-422. doi: 10. 1002/(SICI)1099-1492(199812)11: 8& 414:: AID-NBM537> 3. 0. CO; 2-W.
20. Jagannathan NR, Kumar M, Raghunathan P et al (1999) Assessment of the therapeutic response of human breast carcinoma using in vivo volume localized proton magnetic resonance spectroscopy. Curr Sci 76: 777-782.
21. Jagannathan NR, Kumar M, Seenu V et al (2001) Evaluation of total choline from in vivo volume localized proton MR spectroscopy and its response to neoadjuvant chemotherapy in locally advanced breast cancer. Br J Cancer 84: 1016-1022 doi: 10. 1054/bjoc. 2000. 1711.
22. Katz-Brull R, Lavin PT, Lenkinski RE (2002a) Clinical utility of proton magnetic resonance spectroscopy in characterizing breast lesions. J Natl Cancer Inst 94: 1197-1203.
23. Katz-Brull R, Seger D, Rivenson-Segal D et al (2002b) Metabolic markers of breast cancer: enhanced choline metabolism and reduced choline-ether-phospholipid synthesis. Cancer Res 62: 1966-1970.
24. Kuhl C (2007) The current status of breast MR imaging. Part I. Choice of technique, image interpretation, diagnostic accuracy and transfer to clinical practice. Radiology 244: 356-378 doi: 10. 1148/radiol. 2442051620.
25. Kumar M, Seenu V, Julka PK et al (2005) Proton MR spectroscopy of human breast cancer. In: Jagannathan NR (ed) Recent advances in MR imaging and spectroscopy. Jaypee, New Delhi, pp 312-344.
26. Kumar M, Jagannathan NR, Seenu V et al (2006) Monitoring the therapeutic response of locally advanced breast cancer patients: sequential in-vivo proton MR spectroscopy study. J Magn Reson Imaging 24: 325-332 doi: 10. 1002/jmri. 20646.
27. 1H MR spectroscopy. J Magn Reson Imaging 10: 159-164 doi: 10. 1002/(SICI)1522-2586(199908)10: 2& 159:: AID-JMRI8> 3. 0. CO; 2-0.
28. Mackinnon WB, Barry PA, Malycha PL et al (1997) Fine-needle biopsy specimens of benign breast lesions distinguished from invasive cancer ex-vivo with proton MR spectroscopy. Radiology 204: 661-666.
29. 1H MR spectroscopy-a pilot study at 4 T. Radiology 233: 424-431 doi: 10. 1148/radiol. 2332031285.
30. 1H MR spectroscopy to improve diagnostic accuracy of breast MR imaging: preliminary results of observer performance study at 4. 0 T. Radiology 236: 465-475 doi: 10. 1148/radiol. 2362040836.
31. Mescher M, Tannus A, Johnson MON et al (1996) Solvent suppression using selective echo dephasing. J Magn Reson 123: 226-229 doi: 10. 1006/jmra. 1996. 0242.
32. Mountford CE, Somorjai RL, Malycha P et al (2001) Diagnosis and prognosis of breast cancer by magnetic resonance spectroscopy of fine-needle aspirates analysed using a statistical classification strategy. Br J Surg 88: 1234-1240 doi: 10. 1046/j. 0007-1323. 2001. 01864. x.
33. Roebuck JR, Cecil KM, Schnall MD et al (1998) Human breast lesions: characterization with proton MR spectroscopy. Radiology 209: 269-275.
34. Sardanelli F, Fausto A, Podo F (2008) MR spectroscopy of the breast. Radiol Med (Torino) 113: 56-64 doi: 10. 1007/s11547-008-0228-y.
35. Seenu V, Pavan Kumar MN et al (2005) Potential of magnetic resonance spectroscopy to detect metastasis in axillary lymph nodes in breast cancer. Magn Reson Imaging 23: 1005-1010 doi: 10. 1016/j. mri. 2005. 10. 004.
36. 1H magnetic resonance spectroscopy: a pilot study. Magn Reson Imaging 22: 697-706 doi: 10. 1016/j. mri. 2004. 01. 037.
37. Sharma U, Jagannathan NR (2006a) In-vivo magnetic resonance (MR) spectroscopy in breast cancer. In: Webb GA (ed) Modern magnetic resonance. Springer, Netherlands, pp 1063-1072.
38. Sharma U, Sharma R, Jagannathan NR (2006b) Characterization of breast lesions by magnetic resonance imaging (MRI) and spectroscopy (MRS). Curr Med Imaging Rev 2: 329-340 doi: 10. 2174/157340506777934525.
39. 31P MR spectroscopy at 1. 5 T. Radiology 169: 615-620.
40. Sitter B, Sonnewald U, Spraul M et al (2002) High-resolution magic angle spinning MRS of breast cancer tissue. NMR Biomed 15: 327-337 doi: 10. 1002/nbm. 775.
41. Sitter B, Lundgren S, Bathen TF et al (2006) Comparison of HR MAS MR spectroscopic profiles of breast cancer tissue with clinical parameters. NMR Biomed 19: 30-40 doi: 10. 1002/nbm. 992.
42. 1H MRS at 1. 5 T. Eur Radiol 15: 1037-1043 doi: 10. 1007/s00330-004-2475-1.
43. Thomas MA, Wyckoff N, Yue K et al (2005) Two-dimensional MR spectroscopic characterization of breast cancer in-vivo. Technol Cancer Res Treat 4: 99-106.
44. 1H NMR metabonomics to breast cancer characterization and detection. Prog Nucl Magn Reson Spectrosc 47: 165-174 doi: 10. 1016/j. pnmrs. 2005. 09. 001.
45. Yeung DK, Cheung HS, Tse GM (2001) Human breast lesions: characterization with contrast-enhanced in-vivo proton MR spectroscopy-initial results. Radiology 220: 40-46.