The end of the line for the surviving sepsis campaign, but not for early goal-directed therapy

Emergency Medicine Journal

Volumn 28, Issue 1, 2011, Pages 3-4

  Nee, Patrick A ^a   Rivers, Emanuel P ^b  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

^b WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; DROTRECOGIN; STEROID;

BLOOD CULTURE; EMERGENCY WARD; EVIDENCE BASED PRACTICE; HEALTH CARE ORGANIZATION; HUMAN; KNOWLEDGE; LACTATE BLOOD LEVEL; LOW DRUG DOSE; MORTALITY; NOTE; OUTCOME ASSESSMENT; PRACTICE GUIDELINE; PRIORITY JOURNAL; RESUSCITATION; SEPSIS; SEPTIC SHOCK; SURVIVAL;

EARLY DIAGNOSIS; EMERGENCY MEDICINE; EMERGENCY SERVICE, HOSPITAL; EVIDENCE-BASED MEDICINE; GREAT BRITAIN; HEALTH PROMOTION; HOSPITAL MORTALITY; HUMANS; INTERNATIONAL COOPERATION; PRACTICE GUIDELINES AS TOPIC; PROGRAM EVALUATION; SEPSIS; SHOCK, SEPTIC; SURVIVAL ANALYSIS;

EID: 78751585480     PISSN: 14720205     EISSN: 14720213     Source Type: Journal    
DOI: 10.1136/emj.2010.097147     Document Type: Note

References (18)

1. Levy MM, Dellinger RP, Townsend SR, et al. The surviving sepsis campaign: results of an international guideline-based performance improvement programme targeting severe sepsis. Crit Care Med 2010;38:367-74.
2. Rivers E, Nguyen B, Havstad S, et al. Early goal-directed therapy in the treatment of severe sepsis and septic shock. N Engl J Med 2001;345:1368-77.
3. Marik PE, Varon J. The hemodynamic derangements in sepsis: implications for treatment strategies. Chest 1998;114:854-60.
4. Shapiro NI, Howell MD, Talmor D, et al. Implementation and outcomes of the multiple urgent sepsis therapies (MUST) protocol. Crit Care Med 2006;34:1025-32.
5. Bellomo R, Reade MC, Warrillow SJ. The pursuit of a high central venous oxygen saturation in sepsis: growing concerns. Crit Care 2008;12:130.
6. Perel A, Maggiorini M, Malbrain M, et al. Optimal hemodynamic management according to the surviving sepsis guidelines is not applicable to all ICU patients. Crit Care 2008;12(Suppl 2):S156.
7. James JH, Luchette FA, McCarter FD, et al. Lactate is an unreliable indicator of tissue hypoxia in injury or sepsis. Lancet 1999;354:505-8.
8. Bruno L. Lactate and shock state: the metabolic view. Curr Opin Crit Care 2006;12:315-21.
9. Ho BC, Bellomo R, McGain F, et al. The incidence and outcome of septic shock patients in the absence of early-goal directed therapy. Crit Care 2006;10:R80.
10. van Beest P, Hofstra J, Schultz M, et al. The incidence of low venous oxygen saturation on admission in the ICU: a multicenter observational study in the Netherlands. Crit Care 2008;12:R33.
11. Majuran M, Clancy M. Determination of the size of the different sepsis categories presenting to a UK teaching hospital emergency department. Emerg Med J 2008;25:11-14. (Pubitemid 351175834)
12. Dellinger RP, Levy MM, Carlet JM, et al. Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock: 2008. Intensive Care Med 2008;34:17-60.
13. http://clinicaltrials.gov/ct2/show/NCT00510835?term=NCT00510835&rank= .
14. Holthaus CV, Cannon C, Elkin R, et al. Can my severe sepsis and septic shock patients wait any longer? Ann Emerg Med 2009;54:135-6.
15. Jones AE, Brown MD, Trzeciak S, et al. The effect of a quantitative resuscitation strategy on mortality in patients with sepsis: a meta-analysis. Crit Care Med 2008;36:2734-9.
16. Rivers EP, Coba V, Whitmill M. Early goal-directed therapy in severe sepsis and septic shock: a contemporary review of the literature. Curr Opin Anaesthesiol 2008;21:128-40.
17. de Oliveira CF, de Oliveira DS, Gottschald AF, et al. ACCM/PALS haemodynamic support guidelines for paediatric septic shock: an outcomes comparison with and without monitoring central venous oxygen saturation. Intensive Care Med 2008;34:1065-75.
18. Cannon C, Holthaus C, Rivers E, et al. Improving outcome in severe sepsis and septic shock: results of a prospective multicenter collaborative. J Emerg Med 2009;37:217-36.