Wild-type transthyretin significantly contributes to the formation of amyloid fibrils in familial amyloid polyneuropathy patients with amyloidogenic transthyretin Val30Met

Human Pathology

Volumn 42, Issue 2, 2011, Pages 236-243

  Tsuchiya Suzuki, Ayako ^a   Yazaki, Masahide ^a   Kametani, Fuyuki ^b   Sekijima, Yoshiki ^a   Ikeda, Shu Ichi ^a  

^a SHINSHU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

Author keywords

Abdominal fat biopsy; Familial amyloid polyneuropathy; Liquid chromatography ion trap mass spectrometry; Senile systemic amyloidosis; Wild type transthyretin

Indexed keywords

AMYLOID; METHIONINE; PREALBUMIN; VALINE;

ABDOMINAL FAT; ADULT; AGED; AGING; ARTICLE; CLINICAL ARTICLE; FAMILIAL AMYLOID POLYNEUROPATHY; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; MALE; WILD TYPE;

ABDOMEN; ADIPOSE TISSUE; ADULT; AGED; AGED, 80 AND OVER; AGING; AMYLOID; AMYLOID NEUROPATHIES, FAMILIAL; AMYLOIDOSIS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FEMALE; HUMANS; MALE; MIDDLE AGED; MUTATION; PREALBUMIN; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; VALINE; YOUNG ADULT;

EID: 78751572631     PISSN: 00468177     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.humpath.2010.06.014     Document Type: Article

References (31)

1. Ikeda S., Nakazato M., Ando Y., and Sobue G. Familial transthyretin-type amyloid polyneuropathy in Japan: clinical and genetic heterogeneity Neurology 58 2002 1001 1007
2. Connors L.H., Lim A., Prokaeva T., Roskens V.A., and Costello C.E. Tabulation of human transthyretin (TTR) variants, 2003 Amyloid 10 2003 160 184
3. Gustavsson A., Engström U., and Westermark P. Normal transthyretin and synthetic transthyretin fragments form amyloid-like fibrils in vitro Biochem Biophys Res Commun 175 1991 1159 1164
4. Westermark P., Sletten K., Johansson B., and Cornwell G.G. 3rd Fibril in senile systemic amyloidosis is derived from normal transthyretin Proc Natl Acad Sci U S A 87 1990 2843 2845
5. Dubrey S.W., Davidoff R., Skinner M., Bergethon P., Lewis D., and Falk R.H. Progression of ventricular wall thickening after liver transplantation for familial amyloidosis Transplantation 64 1997 74 80
6. Stangou A.J., Hawkins P.N., and Heaton N.D. Progressive cardiac amyloidosis following liver transplantation for familial amyloid polyneuropathy: implications for amyloid fibrillogenesis Transplantation 66 1998 229 233
7. Yazaki M., Tokuda T., and Nakamura A. Cardiac amyloid in patients with familial amyloid polyneuropathy consists of abundant wild-type transthyretin Biochem Biophys Res Commun 274 2000 702 706
8. Yazaki M., Mitsuhashi S., and Tokuda T. Progressive wild-type transthyretin deposition after liver transplantation preferentially occurs onto myocardium in FAP patients Am J Transplant 7 2007 235 242
9. Tsuchiya A., Yazaki M., Kametani F., Takei Y., and Ikeda S. Marked regression of abdominal fat amyloid in patients with familial amyloid polyneuropathy during long-term follow-up after liver transplantation Liver Transpl 14 2008 563 570
10. Tojo K., Sekijima Y., Kelly J.W., and Ikeda S. Diflunisal stabilizes familial amyloid polyneuropathy-associated transthyretin variant tetramers in serum against dissociation required for amyloidogenesis Neurosci Res 56 2006 441 449
11. Ikeda S., Nakano T., Yanagisawa N., Nakazato M., and Tsukagoshi H. Asymptomatic homozygous gene carrier in a family with type I familial amyloid polyneuropathy Eur Neurol 32 1992 308 313
12. Maruyama K., Ikeda S., Yanagisawa N., and Nakazato M. Diagnostic value of abdominal fat tissue aspirate in familial amyloid polyneuropathy J Neurol Sci 81 1987 11 18
13. Hazenberg B.P., Limburg P.C., Bijzet J., and van Rijswijk M.H. A quantitative method for detecting deposits of amyloid A protein in aspirated fat tissue of patients with arthritis Ann Rheum Dis 58 1999 96 102
14. Ihse E., Ybo A., Suhr O., Lindqvist P., Backman C., and Westermark P. Amyloid fibril composition is related to the phenotype of hereditary transthyretin V30M amyloidosis J Pathol 216 2008 253 261
15. Araki S., Mawatari S., Ohta M., Nakajima A., and Kuroiwa Y. Polyneuritic amyloidosis in a Japanese family Arch Neurol 18 1968 593 602
16. Kito S., Itoga E., Kamiya K., Kishida T., and Yamamura Y. Studies on familial amyloid polyneuropathy in Ogawa Village, Japan Eur Neurol 19 1980 141 151
17. K. Tojo, A. Tsuchiya-Suzuki, T. Sekijima, H. Morita, N. Sumita, and S. Ikeda Upper limb neuropathy such as carpal tunnel syndrome as an initial manifestation of ATTR Val30Met familial amyloid polyneuropathy Amyloid 17 2010 32 35
18. Sekijima Y., Wiseman R.L., and Matteson J. The biological and chemical basis for tissue-selective amyloid disease Cell 121 2005 73 85
19. Westermark P., Sletten K., and Olofsson B.O. Prealbumin variants in the amyloid fibrils of Swedish familial amyloidotic polyneuropathy Clin Exp Immunol 69 1987 695 701
20. Koike H., Ando Y., and Ueda M. Distinct characteristics of amyloid deposits in early- and late-onset transthyretin Val30Met familial amyloid polyneuropathy J Neurol Sci 287 2009 178 184
21. Westermark P., Bergström J., Solomon A., Murphy C., and Sletten K. Transthyretin-derived senile systemic amyloidosis: clinicopathologic and structural considerations Amyloid 10 Suppl 1 2003 48 54
22. Yamano M., Azuma A., Yazaki M., Ikeda S., Sawada T., and Matsubara H. Early cardiac involvement in senile systemic amyloidosis: a case report Amyloid 15 2008 54 59
23. Kyle R.A., Spittell P.C., and Gertz M.A. The premortem recognition of systemic senile amyloidosis with cardiac involvement Am J Med 101 1996 395 400
24. Fuchs U., Zittermann A., and Suhr O. Heart transplantation in a 68-year-old patient with senile systemic amyloidosis Am J Transplant 5 2005 1159 1162
25. Kodaira M., Sekijima Y., and Tojo K. Non-senile wild-type transthyretin systemic amyloidosis presenting as bilateral carpal tunnel syndrome J Peripher Nerv Syst 13 2008 148 150
26. Koike H., Misu K., and Sugiura M. Pathology of early- vs late-onset TTR Met30 familial amyloid polyneuropathy Neurology 63 2004 129 138
27. Bergström J., Gustavsson A., and Hellman U. Amyloid deposits in transthyretin-derived amyloidosis: cleaved transthyretin is associated with distinct amyloid morphology J Pathol 206 2005 224 232
28. Koike H., Misu K., and Ikeda S. Type I (transthyretin Met30) familial amyloid polyneuropathy in Japan: early- vs late-onset form Arch Neurol 59 2002 1771 1776
29. Hattori T., Takei Y., Koyama J., Nakazato M., and Ikeda S. Clinical and pathological studies of cardiac amyloidosis in transthyretin type familial amyloid polyneuropathy Amyloid 10 2003 229 239
30. Cornwell G.G. 3rd, Murdoch W.L., Kyle R.A., Westermark P., and Pitkänen P. Frequency and distribution of senile cardiovascular amyloid. A clinicopathologic correlation Am J Med 75 1983 618 623
31. Pitkänen P., Westermark P., and Cornwell G.G. Senile systemic amyloidosis Am J Pathol 117 1984 391 399