Cancer/testis antigen expression on mesenchymal stem cells isolated from different tissues

Anticancer Research

Volumn 30, Issue 12, 2010, Pages 5023-5028

  Saldanha Araujo, Felipe ^a   Haddad, Rodrigo ^a   Zanette, Dalila Lucíola ^a   De Araujo, Amélia Goes ^a   Orellana, Maristela Delgado ^a   Covas, Dimas Tadeu ^a   Zago, Marco Antonio ^a   Panepucci, Rodrigo Alexandre ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Cancer testis antigens; Fibroblasts; MAGED1; Mesenchymal stem cells; Pericytes; PRAME

Indexed keywords

CANCER TESTIS ANTIGEN; MESSENGER RNA;

ADIPOCYTE; ANTIGEN EXPRESSION; ARTICLE; CANCER CELL CULTURE; CELL DIFFERENTIATION; FIBROBLAST; HUMAN; HUMAN CELL; HUMAN TISSUE; MESENCHYMAL STEM CELL; PERICYTE; PRIORITY JOURNAL; TISSUE; UMBILICAL VEIN ENDOTHELIAL CELL;

ANTIGENS, NEOPLASM; FIBROBLASTS; HUMANS; IMMUNOPHENOTYPING; MEMBRANE PROTEINS; MESENCHYMAL STEM CELLS; NEOPLASM PROTEINS; PERICYTES;

EID: 78751562492     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (41)

1. Caballero OL and Chen YT: Cancer/testis (CT) antigens: potential targets for immunotherapy. Cancer Sci 100: 2014-2021, 2009.
2. Scanlan MJ, Simpson AJ and Old LJ: The cancer/testis genes: review, standardization, and commentary. Cancer Immun 4: 1, 2004.
3. Cronwright G, Le BK, Gotherstrom C, Darcy P, Ehnman M and Brodin B: Cancer/testis antigen expression in human mesenchymal stem cells: down-regulation of SSX impairs cell migration and matrix metalloproteinase 2 expression. Cancer Res 65: 2207-2215, 2005. (Pubitemid 40490129)
4. Dominici M, Le BK, Mueller I, Slaper-Cortenbach I, Marini F, Krause D, Deans R, Keating A, Prockop D and Horwitz E: Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement. Cytotherapy 8: 315-317, 2006.
5. Kerkis I, Kerkis A, Dozortsev D, Stukart-Parsons GC, Gomes Massironi SM, Pereira LV, Caplan AI and Cerruti HF: Isolation and characterization of a population of immature dental pulp stem cells expressing OCT-4 and other embryonic stem cell markers. Cells Tissues Organs 184: 105-116, 2006. (Pubitemid 46558930)
6. Lee OK, Kuo TK, Chen WM, Lee KD, Hsieh SL and Chen TH: Isolation of multipotent mesenchymal stem cells from umbilical cord blood. Blood 103: 1669-1675, 2004. (Pubitemid 38268958)
7. Secco M, Zucconi E, Vieira NM, Fogaca LL, Cerqueira A, Carvalho MD, Jazedje T, Okamoto OK, Muotri AR and Zatz M: Multipotent stem cells from umbilical cord: cord is richer than blood! Stem Cells 26: 146-150, 2008.
8. Zuk PA, Zhu M, Ashjian P, De Ugarte DA, Huang JI, Mizuno H, Alfonso ZC, Fraser JK, Benhaim P and Hedrick MH: Human adipose tissue is a source of multipotent stem cells. Mol Biol Cell 13: 4279-4295, 2002. (Pubitemid 35471185)
9. Covas DT, Panepucci RA, Fontes AM, Silva WA Jr., Orellana MD, Freitas MC, Neder L, Santos AR, Peres LC, Jamur MC and Zago MA: Multipotent mesenchymal stromal cells obtained from diverse human tissues share functional properties and geneexpression profile with CD 146+ perivascular cells and fibroblasts. Exp Hematol 56: 642-654, 2008.
10. Crisan M, Yap S, Casteilla L, Chen CW, Corselli M, Park TS, Andriolo G, Sun B, Zheng B, Zhang L, Norotte C, Teng PN, Traas J, Schugar R, Deasy BM, Badylak S, Buhring HJ, Giacobino JP, Lazzari L, Huard J and Peault B: A perivascular origin for mesenchymal stem cells in multiple human organs. Cell Stem Cell 5: 301-313, 2008.
11. Panepucci RA, Siufi JL, Silva WA, Jr., Proto-Siquiera R, Neder L, Orellana M, Rocha V, Covas DT and Zago MA: Comparison of gene expression of umbilical cord vein and bone marrowderived mesenchymal stem cells. Stem Cells 22: 1263-1278, 2004. (Pubitemid 39646504)
12. Covas DT, Piccinato CE, Orellana MD, Siufi JL, Silva WA, Jr., Proto-Siqueira R, Rizzatti EG, Neder L, Silva AR, Rocha V and Zago MA: Mesenchymal stem cells can be obtained from the human saphena vein. Exp Cell Res 309: 340-344, 2005.
13. Covas DT, Siufi JL, Silva AR and Orellana MD: Isolation and culture of umbilical vein mesenchymal stem cells. Braz J Med Biol Res 36: 1179-1183, 2003.
14. Silva WA Jr., Covas DT, Panepucci RA, Proto-Siqueira R, Siufi JL, Zanette DL, Santos AR and Zago MA: The profile of gene expression of human marrow mesenchymal stem cells. Stem Cells 21: 661-669, 2003.
15. Doherty MJ, Ashton BA, Walsh S, Beresford JN, Grant ME and Canfield AE: Vascular pericytes express osteogenic potential in vitro and in vivo. J Bone Miner Res 13: 828-838, 1998.
16. Takashima A: Establishment of fibroblast cultures. In: Current Protocols in Cell Biology (Bonifacino JS DMHJea ed). New York, John Wiley & Sons, Inc, 1998, pp. 2.1.1-2.1.12.
17. Jaffe EA, Nachman RL, Becker CG and Minick CR: Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria. J Clin Invest 52: 2745-2756, 1973.
18. Pfaffl MW: A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res 29: e45, 2001.
19. Costa FF, Le BK and Brodin B: Concise review: cancer/testis antigens, stem cells, and cancer. Stem Cells 25: 707-711, 2007.
20. Boon T, Cerottini JC, Van den EB, van der BP and Van PA: Tumor antigens recognized by T lymphocytes. Annu Rev Immunol 12: 337-365, 1994.
21. Xiao J and Chen HS: Biological functions of melanomaassociated antigens. World J Gastroenterol 10: 1849-1853, 2004.
22. Chu CS, Xue B, Tu C, Feng ZH, Shi YH, Miao Y and Wen CJ: NRAGE suppresses metastasis of melanoma and pancreatic cancer in vitro and in vivo. Cancer Lett 250: 268-275, 2007.
23. Wen CJ, Xue B, Qin WX, Yu M, Zhang MY, Zhao DH, Gao X, Gu JR and Li CJ: hNRAGE, a human neurotrophin receptor interacting MAGE homologue, regulates p53 transcriptional activity and inhibits cell proliferation. FEBS Lett 564: 171-176, 2004. (Pubitemid 38490720)
24. Nicholaou T, Ebert L, Davis ID, Robson N, Klein O, Maraskovsky E, Chen W and Cebon J: Directions in the immune targeting of cancer: lessons learned from the cancer-testis Ag NY-ESO-1. Immunol Cell Biol 84: 303-317, 2006.
25. Scanlan MJ, Gure AO, Jungbluth AA, Old LJ and Chen YT: Cancer/testis antigens: an expanding family of targets for cancer immunotherapy. Immunol Rev 188: 22-32, 2002.
26. Bandic D, Juretic A, Sarcevic B, Separovic V, Kujundzic-Tiljak M, Hudolin T, Spagnoli GC, Covic D and Samija M: Expression and possible prognostic role of MAGE-A4, NY-ESO-1, and HER-2 antigens in women with relapsing invasive ductal breast cancer: retrospective immunohistochemical study. Croat Med J 47: 32-41, 2006.
27. Odunsi K, Qian F, Matsuzaki J, Mhawech-Fauceglia P, Andrews C, Hoffman EW, Pan L, Ritter G, Villella J, Thomas B, Rodabaugh K, Lele S, Shrikant P, Old LI and Gnjatic S: Vaccination with an NY-ESO-1 peptide of HLA class I/II specificities induces integrated humoral and T cell responses in ovarian cancer. Proc Natl Acad Sci USA 104: 12837-12842, 2007. (Pubitemid 47255241)
28. Valmori D, Souleimanian NE, Tosello V, Bhardwaj N, Adams S, O'Neill D, Pavlick A, Escalon JB, Cruz CM, Angiulli A, Angiulli F, Mears G, Vogel SM, Pan L, Jungbluth AA, Hoffmann EW, Venhaus R, Ritter G, Old LJ and Ayyoub M: Vaccination with NY-ESO-1 protein and CpG in Montanide induces integrated antibody/Th1 responses and CD8 T cells through cross-priming. Proc Natl Acad Sci USA 104: 8947-8952, 2007.
29. Cebon J, Knights A, Ebert L, Jackson H and Chen W: Evaluation of cellular immune responses in cancer vaccine recipients: lessons from NY-ESO-1. Expert Rev Vaccines 9: 617-629, 2010.
30. Tysnes BB and Bjerkvig R: Cancer initiation and progression: involvement of stem cells and the microenvironment. Biochim Biophys Acta 1775: 283-297, 2007.
31. Trosko JE: From adult stem cells to cancer stem cells - Oct-4 gene, cell-cell communication, and hormones during tumor promotion. Ann N Y Acad Sci 1089: 36-58, 2006.
32. Serakinci N, Guldberg P, Burns JS, Abdallah B, Schrodder H, Jensen T and Kassem M: Adult human mesenchymal stem cell as a target for neoplastic transformation. Oncogene 23: 5095-5098, 2004.
33. Joyner DE, Damron TA, Aboulafia A, Bokor W, Bastar JD and Randall RL: Heterogeneous expression of melanoma antigen (hMAGE) mRNA in mesenchymal neoplasia. Tissue Antigens 65: 19-27, 2006.
34. Jungbluth AA, Chen YT, Stockert E, Busam KJ, KoIb D, Iversen K, Coplan K, Williamson B, Altorki N and Old LJ: Immunohistochemical analysis of NY-ESO-1 antigen expression in normal and malignant human tissues. Int J Cancer 92: 856-860, 2001. (Pubitemid 32467376)
35. Sugita Y, Wada H, Fujita S, Nakata T, Sato S, Noguchi Y, Jungbluth AA, Yamaguchi M, Chen YT, Stocken E, Gnjatic S, Williamson B, Scanlan MJ, Ono T, Sakita I, Yasui M, Miyoshi Y, Tamaki Y, Matsuura N, Noguchi S, Old LJ, Nakayama E and Monden M: NY-ESO-1 expression and immunogenicity in malignant and benign breast tumors. Cancer Res 64: 2199-2204, 2004. (Pubitemid 38339473)
36. Doolan P, Clynes M, Kennedy S, Mehta JP, Crown J and O'Driscoll L: Prevalence and prognostic and predictive relevance of PRAME in breast cancer. Breast Cancer Res and Treat 109: 359-365, 2008. (Pubitemid 351644842)
37. Oberthuer A, Hero B, Spitz R, Berthold F and Fischer M: The tumor-associated antigen PRAME is universally expressed in high-stage neuroblastoma and associated with poor outcome. Clin Cancer Res 10: 4307-4313, 2004.
38. Steinbach D, Hermann J, Viehmann S, Zintl F and Gruhn B: Clinical implications of PRAME gene expression in childhood acute myeloid leukemia. Cancer Genet Cytogenet 133: 118-123, 2002. (Pubitemid 34279642)
39. Paydas S: Is everything known in all faces of iceberg in PRAME? Leuk Res 32: 1356-1357, 2008.
40. Proto-Siqueira R, Figueiredo-Pontes LL, Panepucci RA, Garcia AB, Rizzatti EG, Nascimento FM, Ishikawa HCF, Larson RE, Falcao RP, Simpson AJ, Gout I, Filonenko V, Rego EM and Zago MA: PRAME is a membrane and cytoplasmic protein aberrantly expressed in chronic lymphocytic leukemia and mantle cell lymphoma. Leuk Res 30: 1333-1339, 2006. (Pubitemid 44307321)
41. Greiner J, Ringhoffer M, Simikopinko O, Szmaragowska A, Huebsch S, Maurer U, Bergmann L and Schmitt M: Simultaneous expression of different immunogenic antigens in acute myeloid leukemia. Exp Hematol 25: 1413-1422, 2000. (Pubitemid 32012543)