The clinical role of high-sensitive troponin assays: update, interpretation, and perspectives;Sul significato clinico del dosaggio delle troponine: Attuali conoscenze, problemi interpretativie prospettive

Recenti Progressi in Medicina

Volumn 101, Issue 11, 2010, Pages 423-428

  Lippi, Giuseppe ^a   Cervellin, Gianfranco ^a  

^a UNIVERSITY HOSPITAL OF PARMA   (Italy)

Author keywords

Acute coronary syndrome; Acute myocardial infarction; Myocardial injury; Troponin

Indexed keywords

TROPONIN;

ANGINA PECTORIS; ARTICLE; DISEASE ASSOCIATION; HEART INFARCTION; HUMAN; ISCHEMIC HEART DISEASE; PROTEIN DETERMINATION; SENSITIVITY ANALYSIS;

ACUTE CORONARY SYNDROME; BIOLOGICAL MARKERS; HUMANS; MYOCARDIAL INFARCTION; SENSITIVITY AND SPECIFICITY; TROPONIN;

EID: 78751542843     PISSN: 00341193     EISSN: 20381840     Source Type: Journal    
DOI: 10.1701/526.6285     Document Type: Article

References (24)

1. Montagnana M, Lippi G, Salvagno GL, Franchini M, Targher G, Guidi GC. Il ruolo del laboratorio clinico nella valutazione di fattori e marcatori di rischio aterosclerotico. Recenti Prog Med 2008; 99: 215-22.
2. Rosamond W, Flegal K, Furie K, Go A, Greenlund K, Haase N, Hailpern SM, et al. Heart disease and stroke statistics - 2008 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation 2008; 117: e25-e146.
3. Nomenclature and criteria for diagnosis of ischemic heart disease. Report of the Joint International Society and Federation of Cardiology/World Health Organization Task Force on standardization of clinical nomenclature. Circulation 1979; 59: 607-09.
4. Montagnana M, Lippi G, Guidi GC. L'approccio diagnostico alla sindrome coronarica acuta. Recenti Prog Med 2005; 96: 171-7.
5. Lippi G, Targher G, Franchini M, Plebani M. Genetic and biochemical heterogeneity of cardiac troponins: clinical and laboratory implications. Clin Chem Lab Med 2009; 47: 1183-94.
6. Hamm CW, Goldmann BU, Heeschen C, Kreymann G, Berger J, Meinertz T. Emergency room triage of patients with acute chest pain by means of rapid testing for cardiac troponin T or troponin I. N Engl J Med 1997; 337: 1648-53.
7. Lindahl B, Toss H, Siegbahn A, Venge P, Wallentin L. Markers of myocardial damage and inflammation in relation to long-term mortality in unstable coronary artery disease. N Engl J Med 2000; 343: 1139-47.
8. Alpert JS, Thygesen K, Antman E, Bassand JP. Myocardial infarction redefined: a consensus document of the Joint European Society of Cardiology/American College of Cardiology Committee for the redefinition of myocardial infarction. J Am Coll Cardiol 2000; 36: 959-69.
9. Kelley WE, Januzzi JL, Christenson RH. Increases of cardiac troponin in conditions other than acute coronary syndrome and heart failure. Clin Chem 2009; 55: 2098-112.
10. Legendre-Bazydlo LA, Haverstick DM, Kennedy JL, Dent JM, Bruns DE. Persistent increase of cardiac troponin I in plasma without evidence of cardiac injury. Clin Chem 2010; 56: 702-5.
11. Lippi G, De Franceschi L, Salvagno GL, Pavan C, Montagnana M, Guidi GC. Cardiac troponin T during sickle cell crisis. Int J Cardiol 2009; 136: 357-8.
12. Apple FS. A new season for cardiac troponin assays: it's time to keep a scorecard. Clin Chem 2009; 55: 1303-6.
13. Lippi G, Tessitore N, Montagnana M, Salvagno GL, Lupo A, Guidi GC. Influence of sampling time and ultrafiltration coefficient of the dialysis membrane on cardiac troponin I and T. Arch Pathol Lab Med 2008; 132: 72-6.
14. Anderson JL, Adams CD, Antman EM, Bridges CR, Califf RM, Casey DE Jr, et al. ACC/AHA 2007 Guidelines for the management of patients with unstable angina/non ST-elevation myocardial infarction: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. Circulation 2007; 116:e148-e304.
15. Lippi G, Montagnana M, Guidi GC. The clinical dilemma of positive results of high-sensitive troponin assays. Am J Cardiol 2009; 103: 1332.
16. Lippi G, Guidi GC, Salvagno GL, Impellizzeri F, Schena F. Highly sensitive cardiac troponin T is not increased by strenuous eccentric exercise. Am J Cardiol 2010; 105: 1043-4.
17. Lippi G, Cervellin G, Plebani M. Sensitive cardiac troponin T assay. N Engl J Med 2010; 362: 1242.
18. Giannoni A, Giovannini S, Clerico A. Measurement of circulating concentrations of cardiac troponin I and T in healthy subjects: a tool for monitoring myocardial tissue renewal? Clin Chem Lab Med 2009; 47: 1167-77.
19. Hickman PE, Potter JM, Aroney C, Koerbin G, Southcott E, Wu AH, et al. Cardiac troponin may be released by ischemia alone, without necrosis. Clin Chim Acta 2010; 411: 318-23.
20. Lippi G, Banfi G. Exercise-related increase of cardiac troponin release in sports: an apparent paradox finally elucidated? Clin Chim Acta 2010; 411: 610-1.
21. Graving J, Kjekshus J. The perfect biomarker in acute coronary syndrome: a challenge for diagnosis, prognosis, and treatment. Eur Heart J 2008; 29: 2827-8.
22. International Federation of Clinical Chemistry. Troponin assay analytical characteristics. http://www.ifcc.org/pdf/scientificactivities/committees/c- smcd/ctn-assay-table-v091209.pdf.
23. Jesse RL On the relative value o fan assay versus that of a test. J Am Coll Cardiol 2010; 55: 2125-8.
24. Goodacre S, Nicholl J, Dixon S, Cross E, Angelini K, Arnold J, et al. Randomized controller trial and economic evaluation of a chest pain observation unit compared with routine care. BMJ 2004; 328: 254-59.