Challenging regimen for long-term conservative treatment of endometrial adenocarcinoma in young women: A case report and review of the literature

Case Reports in Oncology

Volumn 3, Issue 3, 2010, Pages 380-385

  Tanmahasamut, Prasong ^a   Wongwananuruk, Thanyarat ^a  

^a MAHIDOL UNIVERSITY   (Thailand)

Author keywords

Endometrial adenocarcinoma; Levonorgestrel intrauterine system; Polycystic ovary syndrome

Indexed keywords

GESTAGEN; LEVONORGESTREL; MEGESTROL ACETATE;

ADENOCARCINOMA; ADULT; ASIAN; CANCER HORMONE THERAPY; CASE REPORT; CONSERVATIVE TREATMENT; DEVICE; DRUG DOSE INCREASE; DRUG DOSE REDUCTION; DRUG SUBSTITUTION; DRUG WITHDRAWAL; ENDOMETRIUM BIOPSY; ENDOMETRIUM CARCINOMA; FEMALE; HUMAN; LONG TERM CARE; NUCLEAR MAGNETIC RESONANCE IMAGING; OVARY POLYCYSTIC DISEASE; PATIENT COUNSELING; PATIENT MONITORING; PRIORITY JOURNAL; REVIEW; THAILAND; THORAX RADIOGRAPHY; TRANSVAGINAL ECHOGRAPHY; TREATMENT OUTCOME;

EID: 78751526394     PISSN: None     EISSN: 16626575     Source Type: Journal    
DOI: 10.1159/000321731     Document Type: Review

References (30)

1. Crissman JD, Azoury RS, Barnes AE, Schellhas HF: Endometrial carcinoma in women 40 years of age or younger. Obstet Gynecol 1981;57:699-704.
2. Kaku T, Matsuo K, Tsukamoto N, Shimamoto T, Sugihara K, Tsuruchi N, et al: Endometrial carcinoma in women aged 40 years or younger: a Japanese experience. Int J Gynecol Cancer 1993;3:147-153.
3. Chiva L, Lapuente F, Gonzalez-Cortijo L, Carballo N, Garcia JF, Rojo A, et al: Sparing fertility in young patients with endometrial cancer. Gynecol Oncol 2008;111:S101-S104.
4. Manchana T, Khemapech N: Endometrial adenocarcinoma in young Thai women. Asian Pac J Cancer Prev 2008;9:283-286.
5. Balen A: Polycystic ovary syndrome and cancer. Hum Reprod Update 2001;7:522-525.
6. Ramirez PT, Frumovitz M, Bodurka DC, Sun CC, Levenback C: Hormonal therapy for the management of grade 1 endometrial adenocarcinoma: a literature review. Gynecol Oncol 2004;95:133-138.
7. Thigpen JT, Brady MF, Alvarez RD, Adelson MD, Homesley HD, Manetta A, et al: Oral medroxyprogesterone acetate in the treatment of advanced or recurrent endometrial carcinoma: a dose-response study by the Gynecologic Oncology Group. J Clin Oncol 1999;17:1736-1744.
8. Topuz S, Kalelioglu I, Iyibozkurt C, Ergun B: Conservative management of a patient with endometrial carcinoma desiring fertility: how to inform? Eur J Gynaecol Oncol 2008;29:661-663.
9. Wang HY, Shen L, Sun Z: [Endometrial adenocarcinoma in women 40 years old or younger by treatment with progestins: report of 6 cases and review of the literatures]. Zhonghua Fu Chan Ke Za Zhi 2006;41:237-241.
10. Geisler HE, Huber CP, Rogers S: Carcinoma of the endometrium in premenopausal women. Am J Obstet Gynecol 1969;104:657-663.
11. Dhar KK, NeedhiRajan T, Koslowski M, Woolas RP: Is levonorgestrel intrauterine system effective for treatment of early endometrial cancer? Report of four cases and review of the literature. Gynecol Oncol 2005;97:924-927.
12. Bahamondes L, Ribeiro-Huguet P, de Andrade KC, Leon-Martins O, Petta CA: Levonorgestrel-releasing intrauterine system (Mirena) as a therapy for endometrial hyperplasia and carcinoma. Acta Obstet Gynecol Scand 2003;82:580-582.
13. Giannopoulos T, Butler-Manuel S, Tailor A: Levonorgestrel-releasing intrauterine system (LNG-IUS) as a therapy for endometrial carcinoma. Gynecol Oncol 2004;95:762-764.
14. Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome (PCOS). Hum Reprod 2004;19:41-47.
15. Kowalczyk CL, Malone J Jr, Peterson EP, Jacques SM, Leach RE: Well-differentiated endometrial adenocarcinoma in an infertility patient with later conception. A case report. J Reprod Med 1999;44:57-60.
16. Lowe MP, Bender D, Sood AK, Davis W, Syrop CH, Sorosky JI: Two successful pregnancies after conservative treatment of endometrial cancer and assisted reproduction. Fertil Steril 2002;77:188-189.
17. Randall TC, Kurman RJ: Progestin treatment of atypical hyperplasia and well-differentiated carcinoma of the endometrium in women under age 40. Obstet Gynecol 1997;90:434-440.
18. Kim YB, Holschneider CH, Ghosh K, Nieberg RK, Montz FJ: Progestin alone as primary treatment of endometrial carcinoma in premenopausal women. Report of seven cases and review of the literature. Cancer 1997;79:320-327.
19. Montz FJ, Bristow RE, Bovicelli A, Tomacruz R, Kurman RJ: Intrauterine progesterone treatment of early endometrial cancer. Am J Obstet Gynecol 2002;186:651-657.
20. Andersson K, Mattsson LA, Rybo G, Stadberg E: Intrauterine release of levonorgestrel - a new way of adding progestogen in hormone replacement therapy. Obstet Gynecol 1992;79:963-967.
21. Boon J, Scholten PC, Oldenhave A, Heintz AP: Continuous intrauterine compared with cyclic oral progestin administration in perimenopausal HRT. Maturitas 2003;46:69-77.
22. Raudaskoski T, Tapanainen J, Tomas E, Luotola H, Pekonen F, Ronni-Sivula H, et al: Intrauterine 10 microg and 20 microg levonorgestrel systems in postmenopausal women receiving oral oestrogen replacement therapy: clinical, endometrial and metabolic response. Bjog 2002;109:136-144.
23. Wildemeersch D, Dhont M: Treatment of nonatypical and atypical endometrial hyperplasia with a levonorgestrel-releasing intrauterine system. Am J Obstet Gynecol 2003;188:1297-1298.
24. Vereide AB, Arnes M, Straume B, Maltau JM, Orbo A: Nuclear morphometric changes and therapy monitoring in patients with endometrial hyperplasia: a study comparing effects of intrauterine levonorgestrel and systemic medroxyprogesterone. Gynecol Oncol 2003;91:526-533.
25. Varma R, Soneja H, Bhatia K, Ganesan R, Rollason T, Clark TJ, et al: The effectiveness of a levonorgestrelreleasing intrauterine system (LNG-IUS) in the treatment of endometrial hyperplasia - a long-term follow-up study. Eur J Obstet Gynecol Reprod Biol 2008;139:169-175.
26. Saez F, Urresola A, Larena JA, Martin JI, Pijuan JI, Schneider J, et al: Endometrial carcinoma: assessment of myometrial invasion with plain and gadolinium-enhanced MR imaging. J Magn Reson Imaging 2000;12:460-466.
27. Zarbo G, Caruso G, Caruso S, Mangano U, Zarbo R: Endometrial cancer: preoperative evaluation of myometrial infiltration magnetic resonance imaging versus transvaginal ultrasonography. Eur J Gynaecol Oncol 2000;21:95-97.
28. Dijkhuizen FP, Mol BW, Brolmann HA, Heintz AP: The accuracy of endometrial sampling in the diagnosis of patients with endometrial carcinoma and hyperplasia: a meta-analysis. Cancer 2000;89:1765-1772.
29. Abu J, Brown L, Ireland D: Endometrial adenocarcinoma following insertion of the levonorgestrel-releasing intrauterine system (Mirena) in a 36-year-old woman. Int J Gynecol Cancer 2006;16:1445-1447.
30. Flemming R, Sathiyathasan S, Jackson A: Endometrioid adenocarcinoma after insertion of a levonorgestrelreleasing intrauterine system. J Minim Invasive Gynecol 2008;15:771-773.