Effects of quinone derivatives, such as 1,4-naphthoquinone, on DNA polymerase inhibition and anti-inflammatory action

Medicinal Chemistry

Volumn 7, Issue 1, 2011, Pages 37-44

  Kobayashi, Kazuki ^a   Nishiumi, Shin ^a   Nishida, Masayuki ^a   Hirai, Midori ^a   Azuma, Takeshi ^a   Yoshida, Hiromi ^c   Mizushina, Yoshiyuki ^c   Yoshida, Masaru ^a,b  

^a KOBE UNIVERSITY   (Japan)

^b KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c KOBE GAKUIN UNIVERSITY   (Japan)

Author keywords

1,4 naphthoquinone; Antiinflammation; DNA polymerase ; Enzyme inhibitor; Lipopolysaccharide (LPS); Nuclear factor (NF) B; Quinone derivatives; Tumor necrosis factor (TNF)

Indexed keywords

1,4 BENZOQUINONE; 1,4 NAPHTHOQUINONE; 5,12 NAPHTHACENEQUINONE; ANTHRAQUINONE; DNA DIRECTED DNA POLYMERASE; DNA DIRECTED DNA POLYMERASE ALPHA; DNA DIRECTED DNA POLYMERASE BETA; DNA DIRECTED DNA POLYMERASE DELTA; DNA DIRECTED DNA POLYMERASE EPSILON; DNA DIRECTED DNA POLYMERASE GAMMA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; QUINONE DERIVATIVE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG EFFECT; DRUG MECHANISM; DRUG POTENCY; DRUG STRUCTURE; ENZYME INHIBITION; FEMALE; HUMAN; INFLAMMATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; ANTHRAQUINONES; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTIFIBRINOLYTIC AGENTS; CATTLE; CELL LINE; DNA-DIRECTED DNA POLYMERASE; ENZYME INHIBITORS; FEMALE; GENES, POL; HUMANS; INFLAMMATION; MACROPHAGES; MICE; MICE, INBRED C57BL; NAPHTHOQUINONES; RATS; VITAMIN K 3;

EID: 78751510668     PISSN: 15734064     EISSN: None     Source Type: Journal    
DOI: 10.2174/157340611794072742     Document Type: Article

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