The role of lamotrigine in the treatment of short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing syndrome

Annals of Pharmacotherapy

Volumn 45, Issue 1, 2011, Pages 108-113

  Rosselli, Jennifer L ^a,b   Karpinski, Julie P ^c,d  

^a SOUTHERN ILLINOIS UNIVERSITY EDWARDSVILLE   (United States)

^b Southern Illinois Healthcare Foundation   (United States)

^c Department of Pharmaceutical Sciences   (United States)

^d FROEDTERT MEMORIAL LUTHERAN HOSPITAL   (United States)

Author keywords

Lamotrigine; SUNCT; Triazines; Trigeminal autonomic cephalgia

Indexed keywords

CARBAMAZEPINE; GABAPENTIN; INDOMETACIN; LAMOTRIGINE; LIDOCAINE; METHYLPREDNISOLONE ACETATE; PREDNISONE; TOPIRAMATE;

ARTICLE; DOSE RESPONSE; DROWSINESS; DRUG DOSE TITRATION; DRUG EFFICACY; DRUG WITHDRAWAL; FATIGUE; HUMAN; LOW DRUG DOSE; MEMORY DISORDER; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); STEVENS JOHNSON SYNDROME; SUNCT SYNDROME; TREATMENT OUTCOME; TREATMENT RESPONSE; TRIGEMINAL AUTONOMIC CEPHALALGIA; UNSPECIFIED SIDE EFFECT;

ANTICONVULSANTS; CALCIUM CHANNEL BLOCKERS; HEADACHE; HUMANS; STEVENS-JOHNSON SYNDROME; SUNCT SYNDROME; TRIAZINES;

EID: 78751507020     PISSN: 10600280     EISSN: None     Source Type: Journal    
DOI: 10.1345/aph.1P462     Document Type: Article

References (26)

1. Headache Classification Committee of the International Headache Society. Classification and diagnostic criteria for headache disorders, cranial neuralgias and facial pain (second edition). Cephalalgia 2004;24:1-160.
2. Cohen AS, Matharu MS, Goadsby PJ. Trigeminal autonomic cephalalgias: current and future treatments. Headache 2007;47:969-80. DOI 10.1111/j.1526-4610. 2007.00839.x (Pubitemid 46944375)
3. Lenaerts ME. Update on the therapy of the trigeminal autonomic cephalalgias. Curr Treat Options Neurol 2008;10:30-5.
4. Pareja JA, Caminero AB, Sjaastad O. SUNCT syndrome: diagnosis and treatment. CNS Drugs 2002;16:373-83.
5. Goadsby PJ. Primary neurovascular headache. In: McMahon SB, Koltzenburg M, eds. Wall and Melzack's textbook of pain. 5th ed. Philadelphia, PA: Elsevier, 2006:866-8.
6. Cohen AS. Short-lasting unilateral neuraligform headache attacks with conjunctival injection and tearing. Cephalagia 2007;27:824-32. DOI 10.1111/j.1468-2982.2007.01352.x (Pubitemid 46961745)
7. Trauninger A, Alkonyi B, Kovács N, Komoly S, Pfund Z. Methylprednisolone therapy for short-term prevention of SUNCT syndrome. Cephalalgia 2009;30:735-9. DOI 10.1111/j.1468-2982.2009.01971.x
8. de Lourdes Figuerola M, Bruera O, Pozzo MJ, Leston J. SUNCT syndrome responding absolutely to steroids in two cases with different etiologies. J Headache Pain 2009;10:55-7. DOI 10.1007/s10194-008-0080-4
9. Graff-Radford SB. SUNCT syndrome responsive to gabapentin (Neurontin). Cephalalgia 2000;20:515-7. DOI 10.1046/j.1468-2982.2000.00065.x (Pubitemid 32273179)
10. Hunt CH, Dodick DW, Bosch EP. SUNCT responsive to gabapentin. Headache 2002;42:525-6. DOI 10.1046/j.1526-4610.2002.02129.x (Pubitemid 37011827)
11. Porta-Etessam J, Benito-Leon J, Martinez-Salio A, Berbel A. Gabapentin in the treatment of SUNCT syndrome. Headache 2002;42:523-4. DOI 10.1046/j.1526-4610.2002.02128.x (Pubitemid 37011826)
12. Etemadifar M, Maghzi AH, Ghasemi M, Chitsaz A, Kaji Esfahani M. Efficacy of gabapentin in the treatment of SUNCT syndrome. Cephalalgia 2008;28:1339-42. DOI 10.1111/j.1468-2982.2008.01673.x
13. Matharu MS, Boes CJ, Goadsby PJ. SUNCT syndrome: prolonged attacks, refractoriness and response to topiramate. Neurology 2002;58:1307.
14. Rossi P, Cesarino F, Faroni J, Malpezzi MG, Sandrini G, Nappi G. SUNCT syndrome successfully treated with topiramate: case reports. Cephalalgia 2003;23:998-1000.
15. Kuhn J, Vosskaemper M, Bewermeyer H. SUNCT syndrome: a possible bilateral case responding to topiramate. Neurology 2005;64:2159.
16. May A, Leone M, Afra J, et al; EFNS Task Force. EFNS guidelines on the treatment of cluster headache and other trigeminal-autonomic cephalalgias. Eur J Neurol 2006;13:1066-77. DOI 10.1111/j.1468-1331.2006.01566.x (Pubitemid 44434311)
17. Product information. Lamictal (lamotrigine). Research Triangle Park, NC: GlaxoSmithKline, May 2009.
18. Williams MH, Broadley SA. SUNCT and SUNA: clinical features and medical treatment. J Clin Neurosci 2008;15:526-34. DOI 10.1016/j.jocn.2006.09.006
19. Leone M, Rigamonti A, Usai S, D'Amico D, Grazzi L, Bussone G. Two new SUNCT cases responsive to lamotrigine. Cephalalgia 2000;20:845-7. DOI 10.1046/j.1468-2982.2000.00128.x (Pubitemid 32154567)
20. Gutierrez-Garcia J. SUNCT syndrome responsive to lamotrigine. Headache 2002;42:823-5. DOI 10.1046/j.1526-4610.2002.02187.x (Pubitemid 35291519)
21. D'Andrea G, Granella F, Ghiotto N, Nappi G. Lamotrigine in the treatment of SUNCT syndrome. Neurology 2001;57:1723-5.
22. D'Andrea G, Granella F, Cadaldini M. Possible usefulness of lamotrigine in the treatment of SUNCT syndrome. Neurology 1999;53:1609.
23. Malik K, Rizvi S, Vaillancourt P. The SUNCT syndrome: successfully treated with lamotrigine. Pain Med 2002;3:167-8.
24. Chakravarty A, Mukherjee A. SUNCT syndrome responsive to lamotrigine: documentation of the first Indian case. Cephalalgia 2003;23:474-5. DOI 10.1046/j.1468-2982.2003.00557.x (Pubitemid 36776064)
25. Piovesan EJ, Siow C, Kowacs PA, Werneck LC. Influence of lamotrigine over the SUNCT syndrome. Arq Neuropsiquiatr 2003;61:691-4.
26. Gupta R, Bhatia MS. Short-lasting unilateral neuralgiform headache with conjunctival injection and tearing: response to antiepileptic dual therapy. Neurol India 2008;56:71-3.