Persistent atrial fibrillation is not associated with thrombomodulin level increase in efficiently anticoagulated patients

Archives of Medical Science

Volumn 6, Issue 6, 2010, Pages 887-891

  Wozakowska Kapłon, Beata ^a,b   Bartkowiak, Radoslaw ^a   Grabowska, Urszula ^a   Janiszewska, Grazyna ^c  

^a Swietokrzyskie Centre of Cardiology   (Poland)

^b University of Humanities and Science   (Poland)

^c MEDICAL UNIVERSITY OF LODZ   (Poland)

Author keywords

Atrial fibrillation; Cardioversion; Thrombomodulin

Indexed keywords

ACENOCOUMAROL; THROMBOMODULIN;

ADULT; ANTICOAGULANT THERAPY; ARTICLE; CARDIOVERSION; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HEART ATRIUM FIBRILLATION; HEART LEFT VENTRICLE CONTRACTION; HEART LEFT VENTRICLE FUNCTION; HUMAN; INTERNATIONAL NORMALIZED RATIO; MALE; PROTEIN BLOOD LEVEL; SINUS RHYTHM;

EID: 78751493039     PISSN: 17341922     EISSN: None     Source Type: Journal    
DOI: 10.5114/aoms.2010.19297     Document Type: Article

References (18)

1. Go AS, Hylek EM, Phillips KA, et al. Prevalence of diagnosed atrial fibrillation in adults: National implications for rhythm management and stroke prevention: The AnTicoagulation and Risk Factors in Atrial Fibrillation (ATRIA) Study. JAMA 2001; 285: 2370-5.
2. Wolf PA, Abbott RD, Kannel WB. Atrial fibrillation as an independent risk factor for stroke: The Framingham Study. Stroke 1991; 22: 983-8.
3. Marin F, Roldán V, Climent VE, et al. Plasma von Willebrand factor, soluble thrombomodulin, and fibrin D-dimer concentrations in acute onset non-rheumatic atrial fibrillation. Heart 2004; 90: 1162-6.
4. Mondillo S, Sabatini L, Agricola E, et al. Correlation between left atrial size, prothrombotic state and markers of endothelial dysfunction in patients with lone chronic nonrheumatic atrial fibrillation. Int J Cardiol 2000; 75: 227-32.
5. Kumagai K, Fukunami M, Ohmori M, Kitabatake A, Kamada T, Hoki N. Increased intracardiovascular clotting in patients with chronic atrial fibrillation. J Am Coll Cardiol 1990; 16: 377-80.
6. Lip GY, Lane D, Van Walraven C, Hart RG. Additive role of plasma von Willebrand factor levels to clinical factors for risk stratification of patients with atrial fibrillation. Stroke 2006; 37: 2294-300.
7. Conway DS, Pearce LA, Chin BS, Hart RG, Lip GY. Prognostic value of plasma von Willebrand factor and soluble P-selectin as indices of endothelial damage and platelet activation in 994 patients with nonvalvular atrial fibrillation. Circulation 2003; 107: 3141-5.
8. Takahashi N, Ishibashi Y, Shimada T, et al. Atrial fibrillation impairs endothelial function of forearm vessels in humans. J Card Fail. 2001; 7: 45-54.
9. Li-Saw-Hee FL, Blann AD, Lip GY. A cross-sectional and diurnal study of thrombogenesis among patients with chronic atrial fibrillation. J Am Coll Cardiol 2000; 35: 1926-31.
10. Hammwöhner M, Ittenson A, Dierkes J, et al. Platelet expression of CD40/CD40 ligand and its relation to inflammatory markers and adhesion molecules in patients with atrial fibrillation. Exp Biol Med 2007; 232: 581-9.
11. Hart RG, Pearce LA, Aguilar MI. Meta-analysis: Antithrombotic therapy to prevent stroke in patients who have nonvalvular atrial fibrillation. Ann Intern Med 2007; 146: 857-67.
12. Salem HH, Maruyama I, Ishii H, Majerus PW. Isolation and characterization of thrombomodulin from human placenta. J Biol Chem 1984; 259: 12246-51.
13. Roldán V, Marín F, Blann AD, et al. Interleukin-6, endothelial activation and thrombogenesis in chronic atrial fibrillation. Eur Heart J 2003; 24: 1373-80.
14. Ikuma H, Wada H, Mori Y, et al. Hemostatic markers in Japanese patients undergoing anticoagulant therapy under thrombo-test monitoring. Blood Coagul Fibrinolysis 1999; 10: 429-34.
15. Li-Saw-Hee FL, Blann AD, Goldsmith I, Lip GY. Indexes of hypercoagulability measured in peripheral blood reflect levels in intracardiac blood in patients with atrial fibrillation secondary to mitral stenosis. Am J Cardiol 1999; 83: 1206-9.
16. Freestone B, Chong AY, Blann AD, Lip GY. The effects of direct current cardioversion for persistent atrial fibrillation on indices of endothelial damage/dysfunction. Thromb Res 2006; 118: 479-85.
17. Freestone B, Chong AY, Nuttall S, Blann AD, Lip GY. Soluble E-selectin, von Willebrand factor, soluble Thrombomodulin, and total body nitrate/nitrite product as indices of endothelial damage/dysfunction in paroxysmal, per-sistent, and permanent atrial fibrillation. Chest 2007; 132: 1253-8.
18. Yamashita T, Sekiguchi A, Iwasaki YK, et al. Throm-bomodulin and Tissue Factor Pathway Inhibitor in endocardium of rapidly paced rat atria. Circulation 2003; 108: 2450-2.