Dutch randomized trial comparing standard catheter-directed thrombolysis versus Ultrasound-accElerated Thrombolysis for thromboembolic infrainguinal disease (DUET): Design and rationale

Trials

Volumn 12, Issue , 2011, Pages

  Schrijver, A Marjolein ^a   Reijnen, Michel M P J ^b   Van Oostayen, Jacques A ^b   Nolthenius, Rudolf P T ^c   Van der Valk, Pieter H M ^c   Hoksbergen, Arjan W J ^d   Lely, Rutger J ^d   Fioole, Bram ^e   Vroegindeweij, Dammis ^e   Van Leersum, Marc ^a   De Vries, Jean Paul P M ^a  

^a ST ANTONIUS HOSPITAL   (Netherlands)

^b RIJNSTATE HOSPITAL   (Netherlands)

^c ALBERT SCHWEITZER HOSPITAL   (Netherlands)

^d VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^e Maasstad Hospital   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

COUMARIN; FIBRINOLYTIC AGENT; HEPARIN; UROKINASE;

ADULT; ARTICLE; BLOOD CLOT LYSIS; BYPASS SURGERY; CATHETER DIRECTED THROMBOLYSIS; CONSERVATIVE TREATMENT; CONTINUOUS INFUSION; DISEASE CLASSIFICATION; FEMALE; FOLLOW UP; HUMAN; INGUINAL REGION; INTERMETHOD COMPARISON; INTERVENTION STUDY; LEG ARTERY; LEG ISCHEMIA; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; NETHERLANDS; PAIN ASSESSMENT; PATIENT SAFETY; RANDOMIZED CONTROLLED TRIAL; TEACHING HOSPITAL; THERAPY EFFECT; THROMBOEMBOLISM; ULTRASOUND ACCELERATED THROMBOLYSIS; CATHETERIZATION; CLINICAL TRIAL; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FIBRINOLYTIC THERAPY; INTRAARTERIAL DRUG ADMINISTRATION; ISCHEMIA; LEG; METHODOLOGY; MULTIMODALITY CANCER THERAPY; PATHOPHYSIOLOGY; TIME; TREATMENT OUTCOME; ULTRASOUND THERAPY; VASCULAR PATENCY; VASCULARIZATION;

ADULT; CATHETERIZATION, PERIPHERAL; COMBINED MODALITY THERAPY; FIBRINOLYTIC AGENTS; HOSPITALS, TEACHING; HUMANS; INFUSIONS, INTRA-ARTERIAL; ISCHEMIA; LOWER EXTREMITY; NETHERLANDS; RESEARCH DESIGN; THROMBOEMBOLISM; THROMBOLYTIC THERAPY; TIME FACTORS; TREATMENT OUTCOME; ULTRASONIC THERAPY; VASCULAR PATENCY;

EID: 78651535802     PISSN: 17456215     EISSN: 17456215     Source Type: Journal    
DOI: 10.1186/1745-6215-12-20     Document Type: Article

References (16)

1. Yeager RA, Moneta GL, Taylor LM, Hamre DW, McConnell DB, Porter JM. Surgical management of severe acute lower extremity ischemia. J Vasc Surg 1992, 15:385-391. 10.1067/mva.1992.33848, 1735899.
2. Graor RA, Risius B, Young JR, Lucas FV, Beven EG, Hertzer NR, et al. Thrombolysis of peripheral arterial bypass grafts: surgical thrombectomy compared with thrombolysis. A preliminary report. J Vasc Surg 1988, 7:347-355. 10.1067/mva.1988.avs0070347, 3123719.
3. Gardiner GA, Harrington DP, Koltun W, Whittemore A, Mannick JA, Levin DC. Salvage of occluded arterial bypass grafts by means of thrombolysis. J Vasc Surg 1989, 9:426-431. 10.1067/mva.1989.vs0090426, 2921792.
4. van den Berg JC. Thrombolysis for acute arterial occlusion. J Vasc Surg 2010,
5. Berridge DC, Kessel DO, Robertson I. Surgery versus thrombolysis for initial management of acute limb ischaemia [Systematic Review]. Cochrane Database of Systematic Reviews 2009, (1).
6. Braaten JV, Goss RA, Francis CW. Ultrasound reversibly disaggregates fibrin fibers. Thromb Haemost 1997, 78:1063-1068.
7. Hardig BM, Persson HW, Olsson SB. Low-energy ultrasound exposure of the streptokinase molecule may enhance but also attenuate its fibrinolytic properties. Thromb Res 2006, 117:713-720. 10.1016/j.thromres.2005.05.027, 15993473.
8. Siddiqi F, Odrljin TM, Fay PJ, Cox C, Francis CW. Binding of tissue-plasminogen activator to fibrin: effect of ultrasound. Blood 1998, 91:2019-2025.
9. Tsivgoulis G, Eggers J, Ribo M, Perren F, Saqqur M, Rubiera M, et al. Safety and efficacy of ultrasound-enhanced thrombolysis: a comprehensive review and meta-analysis of randomized and nonrandomized studies. Stroke 2010, 41:280-287. 10.1161/STROKEAHA.109.563304, 20044531.
10. Parikh S, Motarjeme A, McNamara T, Raabe R, Hagspiel K, Benenati JF, et al. Ultrasound-accelerated thrombolysis for the treatment of deep vein thrombosis: initial clinical experience. J Vasc Interv Radiol 2008, 19:521-528. 10.1016/j.jvir.2007.11.023, 18375296.
11. Wissgott C, Richter A, Kamusella P, Steinkamp HJ. Treatment of critical limb ischemia using ultrasound-enhanced thrombolysis (PARES Trial): final results. J Endovasc Ther 2007, 14:438-443. 10.1583/1545-1550(2007)14[438:TOCLIU]2.0.CO;2, 17696616.
12. Motarjeme A. Ultrasound-enhanced Thrombolysis. J Endovasc Ther 2007, 14:251-256. 10.1583/1545-1550(2007)14[251:UT]2.0.CO;2, 17484537.
13. Ouriel K, Veith FJ, Sasahara AA. A comparison of recombinant urokinase with vascular surgery as initial treatment for acute arterial occlusion of the legs. Thrombolysis or Peripheral Arterial Surgery (TOPAS) Investigators. N Engl J Med 1998, 338:1105-1111. 10.1056/NEJM199804163381603, 9545358.
14. Rutherford RB, Baker JD, Ernst C, Johnston KW, Porter JM, Ahn S, et al. Recommended standards for reports dealing with lower extremity ischemia: revised version. J Vasc Surg 1997, 26:517-538. 10.1016/S0741-5214(97)70045-4, 9308598.
15. Ellenberg SS, F T, D D. Data monitoring committees in clinical trials: a practical perspective 2002, Chichester: John Wiley & Sons.
16. Dormandy JA, Rutherford RB. Management of peripheral arterial disease (PAD). TASC Working Group. TransAtlantic Inter-Society Consensus (TASC). J Vasc Surg 2000, 31:S1-S296. 10.1016/S0741-5214(00)81002-2, 10666287.