Ultrasonography and the ultrasound-based management of thyroid nodules: Consensus statement and recommendations

Korean Journal of Radiology

Volumn 12, Issue 1, 2011, Pages 1-14

  Moon, Won Jin ^a   Baek, Jung Hwan ^b   Jung, So Lyung ^c   Kim, Dong Wook ^d   Kim, Eun Kyung ^e   Kim, Ji Young ^c   Kwak, Jin Young ^e   Lee, Jeong Hyun ^b   Lee, Joon Hyung ^f   Lee, Young Hen ^g   Na, Dong Gyu ^h,i   Park, Jeong Seon ^j   Park, Sun Won ^k  

^a Konkuk University Hospital   (South Korea)

^b University of Ulsan College of Medicine   (South Korea)

^c The Catholic University of Korea   (South Korea)

^d Inje University College of Medicine   (South Korea)

^e Yonsei University College of Medicine   (South Korea)

^f Dong A University College of Medicine   (South Korea)

^g Korea University College of Medicine   (South Korea)

^h Seoul National University Hospital   (South Korea)

ⁱ Seoul National University Hospital Healthcare System Gangnam Center   (South Korea)

^j Hanyang University College of Medicine   (South Korea)

^k Seoul National University College of Medicine   (South Korea)

more..

Author keywords

Thyroid, aspiration biopsy; Thyroid, neoplasms; Thyroid, US

Indexed keywords

ASPIRATION BIOPSY; CALCIFICATION; CANCER INVASION; CANCER SURVIVAL; COLOR ULTRASOUND FLOWMETRY; CYTOLOGY; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; DIFFERENTIAL DIAGNOSIS; DOPPLER ECHOGRAPHY; ECHOGRAPHY; ELASTOGRAPHY; FOLLOW UP; HUMAN; PROGNOSIS; REVIEW; SCREENING TEST; SENSITIVITY AND SPECIFICITY; THYROID NODULE; THYROID PAPILLARY CARCINOMA; THYROID TUMOR; TUMOR VASCULARIZATION;

BIOPSY, FINE-NEEDLE; DIAGNOSIS, DIFFERENTIAL; HUMANS; THYROID GLAND; THYROID NEOPLASMS; THYROID NODULE; ULTRASONOGRAPHY, INTERVENTIONAL;

EID: 78651518892     PISSN: 12296929     EISSN: None     Source Type: Journal    
DOI: 10.3348/kjr.2011.12.1.1     Document Type: Review

References (63)

1. Harach HR, Franssila KO, Wasenius VM. Occult papillary carcinoma of the thyroid. A "normal" fi nding in Finland. A systematic autopsy study. Cancer 1985;56:531-538
2. Brander A, Viikinkoski P, Nickels J, Kivisaari L. Thyroid gland: US screening in a random adult population. Radiology 1991;181:683-687
3. Tan GH, Gharib H. Thyroid incidentalomas: management approaches to nonpalpable nodules discovered incidentally on thyroid imaging. Ann Intern Med 1997;126:226-231
4. Frates MC, Benson CB, Charboneau JW, Cibas ES, Clark OH, Coleman BG, et al. Management of thyroid nodules detected at US: Society of Radiologists in Ultrasound consensus conference statement. Radiology 2005;237:794-800
5. Nam-Goong IS, Kim HY, Gong G, Lee HK, Hong SJ, Kim WB, et al. Ultrasonography-guided fi ne-needle aspiration of thyroid incidentaloma: correlation with pathological fi ndings. Clin Endocrinol (Oxf) 2004;60:21-28
6. National Cancer Information Center K. 2005 annual report of the Korea central cancer registry [wwwdocument]. Available at: http://www.cancer.go.krlast accessed; Oct 2008
7. Gharib H, Papini E, Valcavi R, Baskin HJ, Crescenzi A, Dottorini ME, et al. American Association of Clinical Endocrinologists and Associazione Medici Endocrinologi medical guidelines for clinical practice for the diagnosis and management of thyroid nodules. Endocr Pract 2006;12:63-102
8. American Thyroid Association (ATA) Guidelines Taskforce on Thyroid Nodules and Differentiated Thyroid Cancer, Cooper DS, Doherty GM, Haugen BR, Kloos RT, Lee SL, et al. Revised American Thyroid Association management guidelines for patients with thyroid nodules and differentiated thyroid cancer. Thyroid 2009;19:1167-1214
9. Moon WJ, Jung SL, Lee JH, Na DG, Baek JH, Lee YH, et al. Benign and malignant thyroid nodules: US differentiation-- multicenter retrospective study. Radiology 2008;247:762-770
10. Moon WJ, Na DG, Jung SL, Lee JH, Kim J, Kim HS, et al. Recommendations for ultrasound-based management of thyroid nodules. In: 62nd Scientifi c Assembly of the Korean Radiological Society. Seoul: The Korean Radiological Society, 2006
11. Brander AE, Viikinkoski VP, Nickels JI, Kivisaari LM. Importance of thyroid abnormalities detected at US screening: a 5-year follow-up. Radiology 2000;215:801-806
12. Kuma K, Matsuzuka F, Yokozawa T, Miyauchi A, Sugawara M. Fate of untreated benign thyroid nodules: results of long-term follow-up. World J Surg 1994;18:495-498
13. Alexander EK, Hurwitz S, Heering JP, Benson CB, Frates MC, Doubilet PM, et al. Natural history of benign solid and cystic thyroid nodules. Ann Intern Med 2003;138:315-318
14. Hoang JK, Lee WK, Lee M, Johnson D, Farrell S. US features of thyroid malignancy: pearls and pitfalls. Radiographics 2007;27:847-860
15. Papini E, Petrucci L, Guglielmi R, Panunzi C, Rinaldi R, Bacci V, et al. Long-term changes in nodular goiter: a 5-year prospective randomized trial of levothyroxine suppressive therapy for benign cold thyroid nodules. J Clin Endocrinol Metab 1998;83:780-783
16. Brauer VF, Eder P, Miehle K, Wiesner TD, Hasenclever H, Paschke R. Interobserver variation for ultrasound determination of thyroid nodule volumes. Thyroid 2005;15:1169-1175
17. Chan BK, Desser TS, McDougall IR, Weigel RJ, Jeffrey RB Jr. Common and uncommon sonographic features of papillary thyroid carcinoma. J Ultrasound Med 2003;22:1083-1090
18. Watters DA, Ahuja AT, Evans RM, Chick W, King WW, Metreweli C, et al. Role of ultrasound in the management of thyroid nodules. Am J Surg 1992;164:654-657
19. Lee MJ, Kim EK, Kwak JY, Kim MJ. Partially cystic thyroid nodules on ultrasound: probability of malignancy and sonographic differentiation. Thyroid 2009;19:341-346
20. Hatabu H, Kasagi K, Yamamoto K, Iida Y, Misaki T, Hidaka A, et al. Cystic papillary carcinoma of the thyroid gland: a new sonographic sign. Clin Radiol 1991;43:121-124
21. Bonavita JA, Mayo J, Babb J, Bennett G, Oweity T, Macari M, et al. Pattern recognition of benign nodules at ultrasound of the thyroid: which nodules can be left alone? AJR Am J Roentgenol 2009;193:207-213
22. Moon WJ, Kwag HJ, Na DG. Are there any specifi c ultrasound fi ndings of nodular hyperplasia ("leave me alone" lesion) to differentiate it from follicular adenoma? Acta Radiol 2009;50:383-388
23. Kim EK, Park CS, Chung WY, Oh KK, Kim DI, Lee JT, et al. New sonographic criteria for recommending fi ne-needle aspiration biopsy of nonpalpable solid nodules of the thyroid. AJR Am J Roentgenol 2002;178:687-691
24. Alexander EK, Marqusee E, Orcutt J, Benson CB, Frates MC, Doubilet PM, et al. Thyroid nodule shape and prediction of malignancy. Thyroid 2004;14:953-958
25. Stavros AT, Thickman D, Rapp CL, Dennis MA, Parker SH, Sisney GA. Solid breast nodules: use of sonography to distinguish between benign and malignant lesions. Radiology 1995;196:123-134
26. Papini E, Guglielmi R, Bianchini A, Crescenzi A, Taccogna S, Nardi F, et al. Risk of malignancy in nonpalpable thyroid nodules: predictive value of ultrasound and color-Doppler features. J Clin Endocrinol Metab 2002;87:1941-1946
27. Reading CC, Charboneau JW, Hay ID, Sebo TJ. Sonography of thyroid nodules: a "classic pattern" diagnostic approach. Ultrasound Q 2005;21:157-165
28. Khoo ML, Asa SL, Witterick IJ, Freeman JL. Thyroid calcifi cation and its association with thyroid carcinoma. Head Neck 2002;24:651-655
29. Peccin S, de Castsro JA, Furlanetto TW, Furtado AP, Brasil BA, Czepielewski MA. Ultrasonography: is it useful in the diagnosis of cancer in thyroid nodules? J Endocrinol Invest 2002;25:39-43
30. Kwak MS, Baek JH, Kim YS, Jeong HJ. Patterns and signifi cance of peripheral calcifi cations of thyroid tumors seen on ultrasound. J Korean Radiol Soc 2005;53:401-405
31. Yoon DY, Lee JW, Chang SK, Choi CS, Yun EJ, Seo YL, et al. Peripheral calcifi cation in thyroid nodules: ultrasonographic features and prediction of malignancy. J Ultrasound Med 2007;26:1349-1355
32. Kim BM, Kim MJ, Kim EK, Kwak JY, Hong SW, Son EJ, et al. Sonographic differentiation of thyroid nodules with eggshell calcifi cations. J Ultrasound Med 2008;27:1425-1430
33. Propper RA, Skolnick ML, Weinstein BJ, Dekker A. The nonspecifi city of the thyroid halo sign. J Clin Ultrasound 1980;8:129-132
34. Lu C, Chang TC, Hsiao YL, Kuo MS. Ultrasonographic fi ndings of papillary thyroid carcinoma and their relation to pathologic changes. J Formos Med Assoc 1994;93:933-938
35. Tamsel S, Demirpolat G, Erdogan M, Nart D, Karadeniz M, Uluer H, et al. Power Doppler US patterns of vascularity and spectral Doppler US parameters in predicting malignancy in thyroid nodules. Clin Radiol 2007;62:245-251
36. Moon HJ, Kwak JY, Kim MJ, Son EJ, Kim EK. Can vascularity at power Doppler US help predict thyroid malignancy? Radiology 2010;255:260-269
37. Lyshchik A, Higashi T, Asato R, Tanaka S, Ito J, Mai JJ, et al. Thyroid gland tumor diagnosis at US elastography. Radiology 2005;237:202-211
38. Kim SJ, Kim EK, Park CS, Chung WY, Oh KK, Yoo HS. Ultrasound-guided fi ne-needle aspiration biopsy in nonpalpable thyroid nodules: is it useful in infracentimetric nodules? Yonsei Med J 2003;44:635-640
39. Wienke JR, Chong WK, Fielding JR, Zou KH, Mittelstaedt CA. Sonographic features of benign thyroid nodules: interobserver reliability and overlap with malignancy. J Ultrasound Med 2003;22:1027-1031
40. Iannuccilli JD, Cronan JJ, Monchik JM. Risk for malignancy of thyroid nodules as assessed by sonographic criteria: the need for biopsy. J Ultrasound Med 2004;23:1455-1464
41. Frates MC, Benson CB, Doubilet PM, Cibas ES, Marqusee E. Can color Doppler sonography aid in the prediction of malignancy of thyroid nodules? J Ultrasound Med 2003;22:127-131
42. Popowicz B, Klencki M, Lewin'ski A, Słowin'ska-Klencka D. The usefulness of sonographic features in selection of thyroid nodules for biopsy in relation to the nodule's size. Eur J Endocrinol 2009;161:103-111
43. Ahuja A, Chick W, King W, Metreweli C. Clinical signifi cance of the comet-tail artifact in thyroid ultrasound. J Clin Ultrasound 1996;24:129-133
44. Kim SH, Kim BS, Jung SL, Lee JW, Yang PS, Kang BJ, et al. Ultrasonographic fi ndings of medullary thyroid carcinoma: a comparison with papillary thyroid carcinoma. Korean J Radiol 2009;10:101-105
45. Jeh SK, Jung SL, Kim BS, Lee YS. Evaluating the degree of conformity of papillary carcinoma and follicular carcinoma to the reported ultrasonographic fi ndings of malignant thyroid tumor. Korean J Radiol 2007;8:192-197
46. Kim DS, Kim JH, Na DG, Park SH, Kim E, Chang KH, et al. Sonographic features of follicular variant papillary thyroid carcinomas in comparison with conventional papillary thyroid carcinomas. J Ultrasound Med 2009;28:1685-1692
47. Mazzaferri EL. Management of a solitary thyroid nodule. N Engl J Med 1993;328:553-559
48. Mazzaferri EL, Jhiang SM. Long-term impact of initial surgical and medical therapy on papillary and follicular thyroid cancer. Am J Med 1994;97:418-428
49. Pazaitou-Panayiotou K, Capezzone M, Pacini F. Clinical features and therapeutic implication of papillary thyroid microcarcinoma. Thyroid 2007;17:1085-1092
50. Baudin E, Travagli JP, Ropers J, Mancusi F, Bruno-Bossio G, Caillou B, et al. Microcarcinoma of the thyroid gland: the Gustave-Roussy Institute experience. Cancer 1998;83:553-559
51. Chow SM, Law SC, Au SK, Mang O, Yau S, Yuen KT, et al. Changes in clinical presentation, management and outcome in 1348 patients with differentiated thyroid carcinoma: experience in a single institute in Hong Kong, 1960-2000. Clin Oncol (R Coll Radiol) 2003;15:329-336
52. Ito Y, Uruno T, Nakano K, Takamura Y, Miya A, Kobayashi K, et al. An observation trial without surgical treatment in patients with papillary microcarcinoma of the thyroid. Thyroid 2003;13:381-387
53. Noguchi S, Yamashita H, Murakami N, Nakayama I, Toda M, Kawamoto H. Small carcinomas of the thyroid. A long-term follow-up of 867 patients. Arch Surg 1996;131:187-191
54. Noguchi S, Yamashita H, Uchino S, Watanabe S. Papillary microcarcinoma. World J Surg 2008;32:747-753
55. Kim DW, Lee EJ, Kim SH, Kim TH, Lee SH, Kim DH, et al. Ultrasound-guided fi ne-needle aspiration biopsy of thyroid nodules: comparison in effi cacy according to nodule size. Thyroid 2009;19:27-31
56. Mazzaferri EL, Sipos J. Should all patients with subcentimeter thyroid nodules undergo fi ne-needle aspiration biopsy and preoperative neck ultrasonography to defi ne the extent of tumor invasion? Thyroid 2008;18:597-602
57. Asanuma K, Kobayashi S, Shingu K, Hama Y, Yokoyama S, Fujimori M, et al. The rate of tumour growth does not distinguish between malignant and benign thyroid nodules. Eur J Surg 2001;167:102-105
58. Erdogan MF, Gursoy A, Erdogan G. Natural course of benign thyroid nodules in a moderately iodine-defi cient area. Clin Endocrinol (Oxf) 2006;65:767-771
59. Cibas ES, Ali SZ. The Bethesda System for Reporting Thyroid Cytopathology. Thyroid 2009;19:1159-1165
60. Alexander EK, Heering JP, Benson CB, Frates MC, Doubilet PM, Cibas ES, et al. Assessment of nondiagnostic ultrasoundguided fi ne needle aspirations of thyroid nodules. J Clin Endocrinol Metab 2002;87:4924-4927
61. Ogawa Y, Kato Y, Ikeda K, Aya M, Ogisawa K, Kitani K, et al. The value of ultrasound-guided fi ne-needle aspiration cytology for thyroid nodules: an assessment of its diagnostic potential and pitfalls. Surg Today 2001;31:97-101
62. Kwak JY, Koo H, Youk JH, Kim MJ, Moon HJ, Son EJ, et al. Value of US correlation of a thyroid nodule with initially benign cytologic results. Radiology 2010;254:292-300
63. Black WC, Welch HG. Advances in diagnostic imaging and overestimations of disease prevalence and the benefi ts of therapy. N Engl J Med 1993;328:1237-1243