The importance of dielectric constant for drug solubility prediction in binary solvent mixtures: Electrolytes and zwitterions in water+ethanol

AAPS PharmSciTech

Volumn 11, Issue 4, 2010, Pages 1726-1729

  Abolghassemi Fakhree, Mohammad Amin ^a   Delgado, Daniel R ^b   Martínez, Fleming ^b   Jouyban, Abolghasem ^c  

^a TABRIZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b UNIVERSIDAD NACIONAL DE COLOMBIA   (Colombia)

^c TABRIZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

dielectric constant; electrolyte; solubility prediction; water+ethanol; zwitterions

Indexed keywords

ALCOHOL; AMPHOLYTE; ELECTROLYTE; SOLVENT;

ARTICLE; DIELECTRIC CONSTANT; DRUG SOLUBILITY; PRIORITY JOURNAL;

DRUG COMPOUNDING; DRUG DISCOVERY; ELECTROLYTES; ETHANOL; FORECASTING; MODELS, CHEMICAL; PHARMACEUTICAL PREPARATIONS; SOLUBILITY; SOLVENTS; WATER;

EID: 78651494270     PISSN: None     EISSN: 15309932     Source Type: Journal    
DOI: 10.1208/s12249-010-9552-3     Document Type: Article

References (14)

1. Jouyban A. Handbook of solubility data for pharmaceuticals. Boca Raton: CRC Press; 2009.
2. A Jouyban 2008 Review of the cosolvency models for predicting solubility of drugs in water-cosolvent mixtures J Pharm Pharm Sci 11 32 58 1:CAS:528:DC%2BD1MXht1ClsLjF 18445363
3. DJ Widenski A Abbas JA Romagnoli 2009 Effect of the solubility model on antisolvent crystallization predicted volume mean size Chem Eng Trans 17 639 44 10.3303/CET0917107
4. Delgado DR, Martínez F, Fakhree MAA, Jouyban A. Study of the solubility of some sodium sulfonamides in ethanol + water cosolvent mixtures. Biomed Int. 2010 (in press).
5. AN Paruta BJ Sciarrone NG Lordi 1962 Correlation between solubility parameters and dielectric constants J Pharm Sci 51 704 5 10.1002/jps.2600510726 1:CAS:528:DyaF38XksVKltrc%3D 10.1002/jps.2600510726 14484124
6. Born M. Volumen und Hydratationswärme der Ionen. Zeitschrift für Physik. 1920;1:45-48. doi: 10.1007/BF01881023.
7. RG Larson H Hunt 1939 Molecular forces and solvent power J Phys Chem 43 417 23 10.1021/j150391a003 1:CAS:528:DyaA1MXjsVaqsg%3D%3D 10.1021/j150391a003
8. Greenstein JP, Winitz M. Chemistry of amino acids, vol. 1. New York: Wiley; 1961.
9. G Akerlof 1932 Dielectric constants of some organic solvent-water mixtures at various temperatures J Am Chem Soc 54 4125 39 10.1021/ja01350a001 1:CAS:528:DyaA3sXmtlyq 10.1021/ja01350a001
10. A Jouyban Sh Soltanpour H-K Chan 2004 A simple relationship between dielectric constant of mixed solvents with solvent composition and temperature Int J Pharm 269 353 60 10.1016/j.ijpharm.2003.09.010 1:CAS:528: DC%2BD3sXhtVWjsr7O 10.1016/j.ijpharm.2003.09.010 14706247 (Pubitemid 38045299)
11. A Reillo M Cordoba B Escalera E Selles M Cordoba Jr 1995 Prediction of sulfamethiazole solubility in dioxane-water mixtures Pharmazie 50 472 5 1:CAS:528:DyaK2MXmvFCnsbk%3D
12. A Beerbower PL Wu A Martin 1984 Expanded solubility parameter approach 1. Naphthalene and benzoic acid in individual solvents J Pharm Sci 73 179 88 1:CAS:528:DyaL2cXhsVCru7g%3D 10.1002/jps.2600730210 6707879
13. A Jouyban WE Acree Jr 2006 In silico prediction of drug solubility in water-ethanol mixtures using Jouyban-Acree model J Pharm Pharm Sci 9 262 9 1:CAS:528:DC%2BD28XhtVGltLvI 16959195
14. A Jouyban Sh Soltanpour WE Acree Jr 2010 Improved prediction of drug solubility in ethanol + water mixtures at various temperatures Biomed Int 1 19 24