Is UV-induced mutation formation in melanocytes different from other skin cells?

Pigment Cell and Melanoma Research

Volumn 24, Issue 1, 2011, Pages 10-12

  Rünger, Thomas M ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

MELANIN;

DNA DAMAGE; FIBROBLAST; HUMAN; INDUCED MUTATION; KERATINOCYTE; MELANOCYTE; MUTAGENESIS; NOTE; OXIDATION; SKIN CELL; ULTRAVIOLET A RADIATION; ULTRAVIOLET B RADIATION; ULTRAVIOLET RADIATION;

ANIMALS; DNA DAMAGE; DNA REPAIR; FIBROBLASTS; HUMANS; KERATINOCYTES; MELANOCYTES; MELANOMA; MUTAGENESIS; MUTATION; PYRIMIDINE DIMERS; SKIN; SKIN NEOPLASMS; ULTRAVIOLET RAYS;

EID: 78651434374     PISSN: 17551471     EISSN: 1755148X     Source Type: Journal    
DOI: 10.1111/j.1755-148X.2010.00802.x     Document Type: Note

References (6)

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2. Hocker, T., and Tsao, H. (2007). Ultraviolet radiation and melanoma: a systematic review and analysis of reported sequence variants. Hum. Mutat. 28, 578-588.
3. Pleasance, E.D., Cheetham, R.K., Stephens, P.J. et al. (2010). A comprehensive catalogue of somatic mutations from a human cancer genome. Nature 463, 191-196.
4. Rünger, T.M. (2008). C to T transition mutations are not solely UVB-signature mutations, because they are also generated by UVA. J. Invest. Dermatol. 128, 2138-2140.
5. Rünger, T.M., and Kappes, U.P. (2008). Mechanisms of mutation formation with long-wave ultraviolet light (UVA). Photodermatol. Photoimmunol. Photomed. 24, 2-10.
6. Wang, Y., DiGiovanna, J.J., Stern, J.B., Hornyak, T.J., Raffeld, M., Khan, S.G., Oh, K.S., Hollander, M.C., Dennis, P.A., and Kraemer, K.H. (2009). Evidence of ultraviolet type mutations in xeroderma pigmentosum melanomas. Proc. Natl Acad. Sci. USA 106, 6279-6284.